F2EWQ2 (F2EWQ2_PANAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inosose dehydratase HAMAP-Rule MF_01672
EC=4.2.1.44 HAMAP-Rule MF_01672

Alternative name(s):
2-keto-myo-inositol dehydratase HAMAP-Rule MF_01672

Gene names

Name:	iolE HAMAP-Rule MF_01672 EMBL BAK13041.1
Ordered Locus Names:	PAJ_2961 EMBL BAK13041.1

Organism

Pantoea ananatis (strain AJ13355) [Complete proteome] [HAMAP]

Taxonomic identifier

932677 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pantoea › Pantoea ananas

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol) By similarity. HAMAP-Rule MF_01672
Catalytic activity	2,4,6/3,5-pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione + H2O. HAMAP-Rule MF_01672
Cofactor	Cobalt or manganese By similarity. HAMAP-Rule MF_01672 Glutathione By similarity. HAMAP-Rule MF_01672
Sequence similarities	Belongs to the IolE/MocC family. HAMAP-Rule MF_01672

Ontologies

Keywords
Ligand	Cobalt HAMAP-Rule MF_01672 Manganese HAMAP-Rule MF_01672
Molecular function	Lyase HAMAP-Rule MF_01672
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	inositol catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	manganese ion binding Inferred from electronic annotation. Source: HAMAP myo-inosose-2 dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F2EWQ2 [UniParc]. Last modified May 31, 2011. Version 1. Checksum: 7890A45CA96E255A	FASTA	298	33,315
	10 20 30 40 50 60 MNNDNVKLAI APIGWTNDDM PELGSENTFQ QTVSEMALAG FSGSEVGSKY PRDPAILKPM 70 80 90 100 110 120 LDIRGIQICN AWFSTFFAQG DKDETLEGFT AHMNFLYEMG ARVIGCSEQS KSIQGTARAV 130 140 150 160 170 180 FDHKPVFNDD EWQRTAEGYN TLADLAAAKG MRVCLHHHMG TGIQTPAEID RFMALTHDNV 190 200 210 220 230 240 GLLYDTGHIY YSEGSQDVML AVLKTHLPRI FHVHLKDVRD EIVAEVRDQH LSFLDGVKKG 250 260 270 280 290 TFTVPGDGVI DFKPVFKILD DYGYQGWMVV EAEQDPALAN PFEYAVKARK YIRENTGL

References

[1]	"Genome sequence of Pantoea ananatis AJ13355." Hara Y. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AJ13355 EMBL BAK13041.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP012032 Genomic DNA. Translation: BAK13041.1.
RefSeq	YP_005935837.1. NC_017531.1.
3D structure databases
ProteinModelPortal	F2EWQ2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAK13041; BAK13041; PAJ_2961.
GeneID	12526282.
KEGG	paj:PAJ_2961.
PATRIC	54227109. VBIPanAna188453_3436.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03335.
OMA	DMPDLGK.
Family and domain databases
Gene3D	3.20.20.150. 1 hit.
HAMAP	MF_01672. IolE.
InterPro	IPR023952. IolE. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Pfam	PF01261. AP_endonuc_2. 1 hit. [Graphical view]
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F2EWQ2_PANAA

Accession

Primary (citable) accession number: F2EWQ2

Entry history

Integrated into UniProtKB/TrEMBL:	May 31, 2011
Last sequence update:	May 31, 2011
Last modified:	May 1, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)