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Protein
Submitted name:

Guanine nucleotide binding protein (G protein), beta polypeptide 3

Gene

GNB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide binding protein (G protein), beta polypeptide 3Imported
Submitted name:
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3Imported
Gene namesi
Name:GNB3Imported
ORF Names:hCG_25935Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000111664.10.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSG00000111664.
ExpressionAtlasiF1T0G5. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiF1T0G5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 340WD_REPEATS_REGIONInterPro annotationAdd BLAST290
Repeati51 – 92WDPROSITE-ProRule annotationAdd BLAST42
Repeati139 – 179WDPROSITE-ProRule annotationAdd BLAST41
Repeati180 – 221WDPROSITE-ProRule annotationAdd BLAST42
Repeati222 – 263WDPROSITE-ProRule annotationAdd BLAST42
Repeati308 – 340WDPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 31Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0286. Eukaryota.
ENOG410XQUX. LUCA.
KOiK07825.
OMAiNMCSIYS.
OrthoDBiEOG091G0A7T.

Family and domain databases

Gene3Di2.120.10.30. 1 hit.
2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR011042. 6-blade_b-propeller_TolB-like.
IPR020472. G-protein_beta_WD-40_rep.
IPR001632. Gprotein_B.
IPR016346. Guanine_nucleotide-bd_bsu.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PANTHERiPTHR19850. PTHR19850. 1 hit.
PfamiView protein in Pfam
PF00400. WD40. 7 hits.
PRINTSiPR00319. GPROTEINB.
PR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 7 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

F1T0G5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT
60 70 80 90 100
LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV
110 120 130 140 150
MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR
160 170 180 190 200
FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI
210 220 230 240 250
SGACDASAKL WDVREGTCRQ TFTGHESDIN AICFFPNGEA ICTGSDDASC
260 270 280 290 300
RLFDLRADQE LICFSHESII CGITSVAFSL SGRLLFAGYD DFNCNVWDSM
310 320 330 340
KSERVGILSG HDNRVSCLGV TADGMAVATG SWDSFLKIWN
Length:340
Mass (Da):37,221
Last modified:May 31, 2011 - v1
Checksum:i896E706A61B8D74F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB593099 mRNA. Translation: BAJ84039.1.
CH471116 Genomic DNA. Translation: EAW88730.1.
RefSeqiNP_002066.1. NM_002075.3.
UniGeneiHs.631657.

Genome annotation databases

GeneIDi2784.
KEGGihsa:2784.

Similar proteinsi

Entry informationi

Entry nameiF1T0G5_HUMAN
AccessioniPrimary (citable) accession number: F1T0G5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: September 27, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.