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F1T0D0

- F1T0D0_HUMAN

UniProt

F1T0D0 - F1T0D0_HUMAN

Protein
Submitted name:

Homeobox protein OTX2

Gene

OTX2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (31 May 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. multicellular organismal development Source: InterPro

    Keywords - Ligandi

    DNA-bindingUniRule annotationImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Homeobox protein OTX2Imported
    Gene namesi
    Name:OTX2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Expressioni

    Gene expression databases

    ArrayExpressiF1T0D0.
    BgeeiF1T0D0.

    Family & Domainsi

    Keywords - Domaini

    HomeoboxUniRule annotationImported

    Phylogenomic databases

    KOiK09326.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR003022. Otx2_TF.
    IPR003025. Otx_TF.
    IPR013851. Otx_TF_C.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF03529. TF_Otx. 1 hit.
    [Graphical view]
    PRINTSiPR01257. OTX2HOMEOBOX.
    PR01255. OTXHOMEOBOX.
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F1T0D0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLLHPSVGY PATPRKQRRE RTTFTRAQLD VLEALFAKTR YPDIFMREEV    50
    ALKINLPESR VQVWFKNRRA KCRQQQQQQQ NGGQNKVRPA KKKTSPAREV 100
    SSESGTSGQF TPPSSTSVPT IASSSAPVSI WSPASISPLS DPLSTSSSCM 150
    QRSYPMTYTQ ASGYSQGYAG STSYFGGMDC GSYLTPMHHQ LPGPGATLSP 200
    MGTNAVTSHL NQSPASLSTQ GYGASSLGFN STTDCLDYKD QTASWKLNFN 250
    ADCLDYKDQT SSWKFQVL 268
    Length:268
    Mass (Da):29,396
    Last modified:May 31, 2011 - v1
    Checksum:i70675C1701E5FC7F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB593057 mRNA. Translation: BAJ84004.1.
    RefSeqiNP_758840.1. NM_172337.2.
    UniGeneiHs.288655.
    Hs.741558.

    Genome annotation databases

    GeneIDi5015.
    KEGGihsa:5015.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB593057 mRNA. Translation: BAJ84004.1 .
    RefSeqi NP_758840.1. NM_172337.2.
    UniGenei Hs.288655.
    Hs.741558.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5015.
    KEGGi hsa:5015.

    Organism-specific databases

    CTDi 5015.

    Phylogenomic databases

    KOi K09326.

    Miscellaneous databases

    GenomeRNAii 5015.
    NextBioi 35505356.

    Gene expression databases

    ArrayExpressi F1T0D0.
    Bgeei F1T0D0.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR003022. Otx2_TF.
    IPR003025. Otx_TF.
    IPR013851. Otx_TF_C.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF03529. TF_Otx. 1 hit.
    [Graphical view ]
    PRINTSi PR01257. OTX2HOMEOBOX.
    PR01255. OTXHOMEOBOX.
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method."
      Oshikawa M., Tsutsui C., Ikegami T., Fuchida Y., Matsubara M., Toyama S., Usami R., Ohtoko K., Kato S.
      Invest. Ophthalmol. Vis. Sci. 52:6662-6670(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiF1T0D0_HUMAN
    AccessioniPrimary (citable) accession number: F1T0D0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 31, 2011
    Last sequence update: May 31, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.