SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F1T0D0

- F1T0D0_HUMAN

UniProt

F1T0D0 - F1T0D0_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Homeobox protein OTX2

Gene
OTX2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. multicellular organismal development Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox protein OTX2Imported
Gene namesi
Name:OTX2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

ArrayExpressiF1T0D0.
BgeeiF1T0D0.

Family & Domainsi

Keywords - Domaini

HomeoboxUniRule annotationImported

Phylogenomic databases

KOiK09326.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF03529. TF_Otx. 1 hit.
[Graphical view]
PRINTSiPR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1T0D0-1 [UniParc]FASTAAdd to Basket

« Hide

MDLLHPSVGY PATPRKQRRE RTTFTRAQLD VLEALFAKTR YPDIFMREEV    50
ALKINLPESR VQVWFKNRRA KCRQQQQQQQ NGGQNKVRPA KKKTSPAREV 100
SSESGTSGQF TPPSSTSVPT IASSSAPVSI WSPASISPLS DPLSTSSSCM 150
QRSYPMTYTQ ASGYSQGYAG STSYFGGMDC GSYLTPMHHQ LPGPGATLSP 200
MGTNAVTSHL NQSPASLSTQ GYGASSLGFN STTDCLDYKD QTASWKLNFN 250
ADCLDYKDQT SSWKFQVL 268
Length:268
Mass (Da):29,396
Last modified:May 31, 2011 - v1
Checksum:i70675C1701E5FC7F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB593057 mRNA. Translation: BAJ84004.1.
RefSeqiNP_758840.1. NM_172337.2.
UniGeneiHs.288655.
Hs.741558.

Genome annotation databases

GeneIDi5015.
KEGGihsa:5015.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB593057 mRNA. Translation: BAJ84004.1 .
RefSeqi NP_758840.1. NM_172337.2.
UniGenei Hs.288655.
Hs.741558.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5015.
KEGGi hsa:5015.

Organism-specific databases

CTDi 5015.

Phylogenomic databases

KOi K09326.

Miscellaneous databases

GenomeRNAii 5015.
NextBioi 35505356.

Gene expression databases

ArrayExpressi F1T0D0.
Bgeei F1T0D0.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF03529. TF_Otx. 1 hit.
[Graphical view ]
PRINTSi PR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method."
    Oshikawa M., Tsutsui C., Ikegami T., Fuchida Y., Matsubara M., Toyama S., Usami R., Ohtoko K., Kato S.
    Invest. Ophthalmol. Vis. Sci. 52:6662-6670(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiF1T0D0_HUMAN
AccessioniPrimary (citable) accession number: F1T0D0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: March 19, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi