F1SVL0 (F1SVL0_METKA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Topoisomerase V EMBL AAM02649.1

Gene names

Ordered Locus Names:

MK1436

Organism

Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) [Reference proteome] [HAMAP]

Taxonomic identifier

190192 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanopyri › Methanopyrales › Methanopyraceae › Methanopyrus › Methanopyrus kandleri

Protein attributes

Sequence length	984 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Isomerase EMBL AAM02649.1
Technical term	3D-structure PDB 4GFJ Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1SVL0 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 63ABCC55177571D6	FASTA	984	112,207
	10 20 30 40 50 60 MALVYDAEFV GSEREFEEER ETFLKGVKAY DGVLATRYLM ERSSSAKNDE ELLELHQNFI 70 80 90 100 110 120 LLTGSYACSI DPTEDRYQNV IVRGVNFDER VQRLSTGGSP ARYAIVYRRG WRAIAKALDI 130 140 150 160 170 180 DEEDVPAIEV RAVKRNPLQP ALYRILVRYG RVDLMPVTVD EVPPEMAGEF ERLIERYDVP 190 200 210 220 230 240 IDEKEERILE ILRENPWTPH DEIARRLGLS VSEVEGEKDP ESSGIYSLWS RVVVNIEYDE 250 260 270 280 290 300 RTAKRHVKRR DRLLEELYEH LEELSERYLR HPLTRRWIVE HKRDIMRRYL EQRIVECALK 310 320 330 340 350 360 LQDRYGIRED VALCLARAFD GSISMIATTP YRTLKDVCPD LTLEEAKSVN RTLATLIDEH 370 380 390 400 410 420 GLSPDAADEL IEHFESIAGI LATDLEEIER MYEEGRLSEE AYRAAVEIQL AELTKKEGVG 430 440 450 460 470 480 RKTAERLLRA FGNPERVKQL AREFEIEKLA SVEGVGERVL RSLVPGYASL ISIRGIDRER 490 500 510 520 530 540 AERLLKKYGG YSKVREAGVE ELREDGLTDA QIRELKGLKT LESIVGDLEK ADELKRKYGS 550 560 570 580 590 600 ASAVRRLPVE ELRELGFSDD EIAEIKGIPK KLREAFDLET AAELYERYGS LKEIGRRLSY 610 620 630 640 650 660 DDLLELGATP KAAAEIKGPE FKFLLNIEGV GPKLAERILE AVDYDLERLA SLNPEELAEK 670 680 690 700 710 720 VEGLGEELAE RVVYAARERV ESRRKSGRQE RSEEEWKEWL ERKVGEGRAR RLIEYFGSAG 730 740 750 760 770 780 EVGKLVENAE VSKLLEVPGI GDEAVARLVP GYKTLRDAGL TPAEAERVLK RYGSVSKVQE 790 800 810 820 830 840 GATPDELREL GLGDAKIARI LGLRSLVNKR LDVDTAYELK RRYGSVSAVR KAPVKELREL 850 860 870 880 890 900 GLSDRKIARI KGIPETMLQV RGMSVEKAER LLERFDTWTK VKEAPVSELV RVPGVGLSLV 910 920 930 940 950 960 KEIKAQVDPA WKALLDVKGV SPELADRLVE ELGSPYRVLT AKKSDLMRVE RVGPKLAERI 970 980 RAAGKRYVEE RRSRRERIRR KLRG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens." Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N., Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A., Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G., Koonin E.V., Kozyavkin S.A. Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.
[2]	"Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies." Rajan R., Prasad R., Taneja B., Wilson S.H., Mondragon A. Nucleic Acids Res. 41:657-666(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.91 ANGSTROMS) OF 1-685.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE009439 Genomic DNA. Translation: AAM02649.1.

RefSeq

NP_614719.1. NC_003551.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4GFJ	X-ray	2.91	A	1-685	[»]

ProteinModelPortal

F1SVL0.

SMR

F1SVL0. Positions 3-519.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAM02649; AAM02649; MK1436.

GeneID

1478031.

KEGG

mka:MK1436.

Family and domain databases

Gene3D

1.10.10.10. 1 hit.

InterPro

IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR024065. TopoV_catalytic_domain.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]

SMART

SM00278. HhH1. 11 hits.
[Graphical view]

SUPFAM

SSF47781. RuvA_2_like. 6 hits.
SSF140979. SSF140979. 2 hits.

ProtoNet

Search...

Other

EvolutionaryTrace

F1SVL0.

Entry information

Entry name

F1SVL0_METKA

Accession

Primary (citable) accession number: F1SVL0

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)