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Protein
Submitted name:

Uncharacterized protein

Gene

OTX2

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl

GO - Biological processi

  1. axon guidance Source: Ensembl
  2. cell fate specification Source: Ensembl
  3. diencephalon morphogenesis Source: Ensembl
  4. dorsal/ventral pattern formation Source: Ensembl
  5. endoderm development Source: Ensembl
  6. eye photoreceptor cell fate commitment Source: Ensembl
  7. inner ear morphogenesis Source: Ensembl
  8. metencephalon development Source: Ensembl
  9. midbrain development Source: Ensembl
  10. neuron fate determination Source: Ensembl
  11. primitive streak formation Source: Ensembl
  12. protein complex assembly Source: Ensembl
  13. somite rostral/caudal axis specification Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:OTX2Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
ProteomesiUP000008227 Componenti: Chromosome 1

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. growth cone Source: Ensembl
  3. nucleus Source: UniProtKB-SubCell
  4. protein complex Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Keywords - Domaini

HomeoboxUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118908.
InParanoidiF1SSM3.
KOiK18490.
OMAiKGPWASC.
OrthoDBiEOG74J98P.
TreeFamiTF351179.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF03529. TF_Otx. 1 hit.
[Graphical view]
PRINTSiPR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1SSM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSYLKQPPY AVNGLSLTTS GMDLLHPSVG YPATPRKQRR ERTTFTRAQL
60 70 80 90 100
DVLEALFAKT RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQQQ
110 120 130 140 150
QNGGQNKVRP AKKKTSPARE VSSESGTSGQ FTPPSSTSVP AISSSSAPVS
160 170 180 190 200
IWSPASISPL SDPLSTSSSC MQRSYPMTYT QASGYSQGYA GSTSYFGGMD
210 220 230 240 250
CGSYLTPMHH QLPGPGTTLS PMGTNAVTSH LNQSPASLST QGYGASSLGF
260 270 280
NSTTDCLDYK DQTASWKLNF NADCLDYKDQ TSSWKFQVL
Length:289
Mass (Da):31,652
Last modified:May 3, 2011 - v1
Checksum:i9088473F3A3E207B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU463093 Genomic DNA. No translation available.
RefSeqiXP_003353539.1. XM_003353491.2.
XP_005660050.1. XM_005659993.1.

Genome annotation databases

EnsembliENSSSCT00000005580; ENSSSCP00000005442; ENSSSCG00000005063.
GeneIDi100512643.
KEGGissc:100512643.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU463093 Genomic DNA. No translation available.
RefSeqiXP_003353539.1. XM_003353491.2.
XP_005660050.1. XM_005659993.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000005580; ENSSSCP00000005442; ENSSSCG00000005063.
GeneIDi100512643.
KEGGissc:100512643.

Organism-specific databases

CTDi5015.

Phylogenomic databases

GeneTreeiENSGT00760000118908.
InParanoidiF1SSM3.
KOiK18490.
OMAiKGPWASC.
OrthoDBiEOG74J98P.
TreeFamiTF351179.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF03529. TF_Otx. 1 hit.
[Graphical view]
PRINTSiPR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Porcine genome sequencing project
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF1SSM3_PIG
AccessioniPrimary (citable) accession number: F1SSM3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: January 7, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.