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Protein
Submitted name:

Pulmonary surfactant-associated protein A

Gene

SFTPA1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Enzyme and pathway databases

ReactomeiR-SSC-166016. Toll Like Receptor 4 (TLR4) Cascade.
R-SSC-391160. Signal regulatory protein family interactions.
R-SSC-5683826. Surfactant metabolism.
R-SSC-5686938. Regulation of TLR by endogenous ligand.

Names & Taxonomyi

Protein namesi
Submitted name:
Pulmonary surfactant-associated protein AImported
Gene namesi
Name:SFTPA1Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 14

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500327031321 – 248Sequence analysisAdd BLAST228

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiF1SER3.
PeptideAtlasiF1SER3.

Expressioni

Gene expression databases

BgeeiENSSSCG00000010336.
ExpressionAtlasiF1SER3. differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini152 – 247C-type lectinInterPro annotationAdd BLAST96

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
GeneTreeiENSGT00700000104102.
OMAiGEEECVE.
OrthoDBiEOG091G0PU5.
TreeFamiTF330481.

Family and domain databases

CDDicd03591. CLECT_collectin_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR033990. Collectin_CTLD.
IPR016187. CTDL_fold.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F1SER3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRWPLALTF LLLAVSGLEC DVKEVCLASP GIPGTPGSHG LPGRDGRDGI
60 70 80 90 100
KGDPGPPGPM GPPGGMAGPP GQDGMIGAPG LPGERGEKGE PGERGPPGLP
110 120 130 140 150
AHLDEELQSA LHEIRHQILQ SMGVLSFQEF MLAVGEKVFS TNGQSVAFDV
160 170 180 190 200
IRELCARAGG RIAAPRSPEE NEAIASIVKK HNTYAYLGLV EGPTAGDFFY
210 220 230 240
LDGTPVNYTN WYPGEPRGRG KEKCVEMYTD GQWNDRNCQQ YRLAICEF
Length:248
Mass (Da):26,497
Last modified:May 3, 2011 - v1
Checksum:i623E655969B1A63A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU469045 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSSSCT00000011314; ENSSSCP00000011022; ENSSSCG00000010336.

Similar proteinsi

Entry informationi

Entry nameiF1SER3_PIG
AccessioniPrimary (citable) accession number: F1SER3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 27, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported