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F1SDX6

- F1SDX6_PIG

UniProt

F1SDX6 - F1SDX6_PIG

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Protein
Submitted name:

Uncharacterized protein

Gene

TGM2

Organism
Sus scrofa (Pig)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei277 – 2771UniRule annotation
Active sitei277 – 2771 By similarity
Active sitei335 – 3351UniRule annotation
Active sitei358 – 3581UniRule annotation
Active sitei358 – 3581 By similarity
Metal bindingi398 – 3981CalciumUniRule annotation
Metal bindingi400 – 4001CalciumUniRule annotation
Metal bindingi447 – 4471CalciumUniRule annotation
Metal bindingi452 – 4521CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. apoptotic cell clearance Source: Ensembl
  2. branching involved in salivary gland morphogenesis Source: Ensembl
  3. negative regulation of endoplasmic reticulum calcium ion concentration Source: Ensembl
  4. peptide cross-linking Source: InterPro
  5. positive regulation of cell adhesion Source: Ensembl
  6. positive regulation of mitochondrial calcium ion concentration Source: Ensembl
  7. salivary gland cavitation Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM2Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
ProteomesiUP000008227: Chromosome 17

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiF1SDX6.
KOiK05625.
OMAiANGRDHH.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1SDX6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEDLILERC DLELEANGRD HHTADLCRER LVVRRGQAFR LTLHFEGRNY
60 70 80 90 100
EPSVDRLTFS AVTGPAPSEE AGTKARFRLS DAAEEGAWRA EVVDQQDNTL
110 120 130 140 150
SLQLSTPASA PIGLYRLNLE ASTGYEGSSF LLGHFTLLFN AWCPADDVYL
160 170 180 190 200
DSDEERQEYV LTQQGFVYQG SAKFIKSIPW NFGQFEDGIL DSCLMLLDVN
210 220 230 240 250
PKFMRDAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGVS
260 270 280 290 300
PMFWIGSVDI LRRWKNHGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN
310 320 330 340 350
YNSAHDQNSN LLIEYFRNEF GEIQSDKSEM IWNFHCWVES WMTRPDLQPG
360 370 380 390 400
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD
410 420 430 440 450
VVDWIRRDDG SVYKSINRSL VVGLKISTKS VGRDEREDIT HTYKYPEGSP
460 470 480 490 500
EEREAFTKAN HLNKLADKEE SEVAMRIRVG EGMNMGSDFD VFAHITNNTA
510 520 530 540 550
EEHTGRLLLC ARTVSYNGVL GPECGTKDLL NFSLEPYSEK SVPLRILYEK
560 570 580 590 600
YCDCLTESNL IKVRGLLIEP AANSYLLAER DIYLENPEIK IRILGEPKQN
610 620 630 640 650
RKLVAEVSLR NPLTTPLSGC IFTVEGAGLT EEQKTVEIPD PVGAGEEVKV
660 670 680
RVDLLPLLVG RHKLVVNFNS NRLKAVKGFR NVIVGPS
Length:687
Mass (Da):77,224
Last modified:May 3, 2011 - v1
Checksum:iBC3D1B64300930BE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU467005 Genomic DNA. No translation available.
RefSeqiXP_003360037.2. XM_003359989.3.
UniGeneiSsc.84061.
Ssc.98088.

Genome annotation databases

EnsembliENSSSCT00000031001; ENSSSCP00000022472; ENSSSCG00000023522.
GeneIDi100154530.
KEGGissc:100154530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU467005 Genomic DNA. No translation available.
RefSeqi XP_003360037.2. XM_003359989.3.
UniGenei Ssc.84061.
Ssc.98088.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSSSCT00000031001 ; ENSSSCP00000022472 ; ENSSSCG00000023522 .
GeneIDi 100154530.
KEGGi ssc:100154530.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
InParanoidi F1SDX6.
KOi K05625.
OMAi ANGRDHH.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Porcine genome sequencing project
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (NOV-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF1SDX6_PIG
AccessioniPrimary (citable) accession number: F1SDX6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3