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Protein
Submitted name:

Transglutaminase 2

Gene

TGM2

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei277UniRule annotation1
Active sitei335UniRule annotation1
Active sitei358UniRule annotation1
Metal bindingi398CalciumUniRule annotation1
Metal bindingi400CalciumUniRule annotation1
Metal bindingi447CalciumUniRule annotation1
Metal bindingi452CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transglutaminase 2Imported
Gene namesi
Name:TGM2Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1SDX6
PeptideAtlasiF1SDX6
PRIDEiF1SDX6

Expressioni

Gene expression databases

BgeeiENSSSCG00000023522

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000022472

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
InParanoidiF1SDX6
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

F1SDX6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDLILERC DLELEANGRD HHTADLCRER LVVRRGQAFR LTLHFEGRNY
60 70 80 90 100
EPSVDRLTFS AVTGPAPSEE AGTKARFRLS DAAEEGAWRA EVVDQQDNTL
110 120 130 140 150
SLQLSTPASA PIGLYRLNLE ASTGYEGSSF LLGHFTLLFN AWCPADDVYL
160 170 180 190 200
DSDEERQEYV LTQQGFVYQG SAKFIKSIPW NFGQFEDGIL DSCLMLLDVN
210 220 230 240 250
PKFMRDAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGVS
260 270 280 290 300
PMFWIGSVDI LRRWKNHGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN
310 320 330 340 350
YNSAHDQNSN LLIEYFRNEF GEIQSDKSEM IWNFHCWVES WMTRPDLQPG
360 370 380 390 400
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD
410 420 430 440 450
VVDWIRRDDG SVYKSINRSL VVGLKISTKS VGRDEREDIT HTYKYPEGSP
460 470 480 490 500
EEREAFTKAN HLNKLADKEE SEVAMRIRVG EGMNMGSDFD VFAHITNNTA
510 520 530 540 550
EEHTGRLLLC ARTVSYNGVL GPECGTKDLL NFSLEPYSEK SVPLRILYEK
560 570 580 590 600
YCDCLTESNL IKVRGLLIEP AANSYLLAER DIYLENPEIK IRILGEPKQN
610 620 630 640 650
RKLVAEVSLR NPLTTPLSGC TFTVEGAGLT EEQKTVEIPD PVGAGEEVKV
660 670 680
RVDLLPLLVG RHKLVVNFNS NRLKAVKGFR NVIVGPS
Length:687
Mass (Da):77,212
Last modified:November 22, 2017 - v2
Checksum:iBC3D0A85C018D14E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000106 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSSSCT00000031001; ENSSSCP00000022472; ENSSSCG00000023522

Similar proteinsi

Entry informationi

Entry nameiF1SDX6_PIG
AccessioniPrimary (citable) accession number: F1SDX6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: November 22, 2017
Last modified: April 25, 2018
This is version 54 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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