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Protein

Glutathione S-transferase

Gene

GSTA4

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotation

Enzyme and pathway databases

ReactomeiREACT_322613. Glutathione conjugation.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:GSTA4Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
ProteomesiUP000008227 Componenti: Chromosome 7

Expressioni

Gene expression databases

GenevisibleiF1S7C8. SS.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000002836.

Structurei

3D structure databases

ProteinModelPortaliF1S7C8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GST superfamily. Alpha family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00670000097856.
InParanoidiF1S7C8.
KOiK00799.
OMAiLELIIMH.
OrthoDBiEOG79CZ0K.
TreeFamiTF105321.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR003080. GST_alpha.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01266. GSTRNSFRASEA.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1S7C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMATKPKLHY PNGRGRMESV RWVLAAAGVE FDEEFLETKE QLQKLQDGNH
60 70 80 90 100
LLFQQVPMVE IDGMKLVQTR SILHYIADKH HLFGKDLKER TLIDMYVEGT
110 120 130 140 150
LDLLELIIMH PFLKPDDQQK EVVNMAQKAI IRYFPVFEKV LRGHGQRFLV
160 170 180 190 200
GNQLSLADII LLQTILALEE KIPNILSAFP HLQEFTVKIS NIPTIKKFLE
210 220
PGSKKKPPPD DIYVRTVYNI FMP
Length:223
Mass (Da):25,802
Last modified:July 11, 2012 - v2
Checksum:i3727E8ED9F549043
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU062466 Genomic DNA. No translation available.
RefSeqiNP_001230308.1. NM_001243379.1.
XP_005666520.1. XM_005666463.1.
UniGeneiSsc.5008.

Genome annotation databases

EnsembliENSSSCT00000002915; ENSSSCP00000002836; ENSSSCG00000002627.
GeneIDi100152951.
KEGGissc:100152951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU062466 Genomic DNA. No translation available.
RefSeqiNP_001230308.1. NM_001243379.1.
XP_005666520.1. XM_005666463.1.
UniGeneiSsc.5008.

3D structure databases

ProteinModelPortaliF1S7C8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000002836.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000002915; ENSSSCP00000002836; ENSSSCG00000002627.
GeneIDi100152951.
KEGGissc:100152951.

Organism-specific databases

CTDi2941.

Phylogenomic databases

GeneTreeiENSGT00670000097856.
InParanoidiF1S7C8.
KOiK00799.
OMAiLELIIMH.
OrthoDBiEOG79CZ0K.
TreeFamiTF105321.

Enzyme and pathway databases

ReactomeiREACT_322613. Glutathione conjugation.

Gene expression databases

GenevisibleiF1S7C8. SS.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR003080. GST_alpha.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01266. GSTRNSFRASEA.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Porcine genome sequencing project
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF1S7C8_PIG
AccessioniPrimary (citable) accession number: F1S7C8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 11, 2012
Last modified: July 22, 2015
This is version 30 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.