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Protein
Submitted name:

Uncharacterized protein

Gene

TMED10

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-SSC-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-SSC-5694530. Cargo concentration in the ER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TMED10Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
ProteomesiUP000008227 Componenti: Chromosome 7

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei186 – 20823HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence analysisAdd
BLAST
Chaini32 – 219188Sequence analysisPRO_5003274586Add
BLAST

Proteomic databases

PaxDbiF1S2Q3.

Expressioni

Gene expression databases

GenevisibleiF1S2Q3. SS.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000002582.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini41 – 193153GOLDInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the EMP24/GP25L family.UniRule annotation
Contains 1 GOLD domain.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410XTBQ. LUCA.
KOG1691. Eukaryota.
GeneTreeiENSGT00550000074954.
InParanoidiF1S2Q3.
OMAiHTLYSKE.
OrthoDBiEOG7PZRZM.
TreeFamiTF313729.

Family and domain databases

InterProiIPR009038. GOLD_dom.
IPR015720. TMP21-related.
[Graphical view]
PANTHERiPTHR22811. PTHR22811. 1 hit.
PfamiPF01105. EMP24_GP25L. 1 hit.
[Graphical view]
PROSITEiPS50866. GOLD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1S2Q3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGLSDPQAL RGPCPLALLL LFLLGPSSVL TISFHLPVNS RKCLREEIHK
60 70 80 90 100
DLLVTGAYEI TDQSGGAGGP RTHLKITDSA GHILYSKEDA TKGKFAFTTE
110 120 130 140 150
DYDMFEVCFE SKGTGRIPDQ LVILDMKHGV EAKNYEEIAK VEKLKPLEVE
160 170 180 190 200
LRRLEDLSES IVNDFAYMKK REEEMRDTNE STNTRVLYFS IFSMFCLIGL
210
ATWQVFYLRR FFKAKKLIE
Length:219
Mass (Da):24,911
Last modified:July 11, 2012 - v2
Checksum:iD47F4CD9B6E3C773
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT737372 Genomic DNA. No translation available.
RefSeqiXP_001926746.1. XM_001926711.4.
UniGeneiSsc.9761.

Genome annotation databases

EnsembliENSSSCT00000002649; ENSSSCP00000002582; ENSSSCG00000002382.
GeneIDi100158015.
KEGGissc:100158015.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT737372 Genomic DNA. No translation available.
RefSeqiXP_001926746.1. XM_001926711.4.
UniGeneiSsc.9761.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000002582.

Proteomic databases

PaxDbiF1S2Q3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000002649; ENSSSCP00000002582; ENSSSCG00000002382.
GeneIDi100158015.
KEGGissc:100158015.

Organism-specific databases

CTDi10972.

Phylogenomic databases

eggNOGiENOG410XTBQ. LUCA.
KOG1691. Eukaryota.
GeneTreeiENSGT00550000074954.
InParanoidiF1S2Q3.
OMAiHTLYSKE.
OrthoDBiEOG7PZRZM.
TreeFamiTF313729.

Enzyme and pathway databases

ReactomeiR-SSC-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-SSC-5694530. Cargo concentration in the ER.

Gene expression databases

GenevisibleiF1S2Q3. SS.

Family and domain databases

InterProiIPR009038. GOLD_dom.
IPR015720. TMP21-related.
[Graphical view]
PANTHERiPTHR22811. PTHR22811. 1 hit.
PfamiPF01105. EMP24_GP25L. 1 hit.
[Graphical view]
PROSITEiPS50866. GOLD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Porcine genome sequencing project
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF1S2Q3_PIG
AccessioniPrimary (citable) accession number: F1S2Q3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 11, 2012
Last modified: December 9, 2015
This is version 32 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.