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Protein
Submitted name:

Uncharacterized protein

Gene

TMED10

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-SSC-5694530. Cargo concentration in the ER.
R-SSC-6807878. COPI-mediated anterograde transport.
R-SSC-6811434. COPI-dependent Golgi-to-ER retrograde traffic.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TMED10Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 7

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei186 – 208HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_500327458632 – 219Sequence analysisAdd BLAST188

Proteomic databases

PaxDbiF1S2Q3.
PeptideAtlasiF1S2Q3.
PRIDEiF1S2Q3.

Expressioni

Gene expression databases

BgeeiENSSSCG00000002382.
GenevisibleiF1S2Q3. SS.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiF1S2Q3. 1 interactor.
STRINGi9823.ENSSSCP00000002582.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 193GOLDInterPro annotationAdd BLAST153

Sequence similaritiesi

Belongs to the EMP24/GP25L family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1691. Eukaryota.
ENOG410XTBQ. LUCA.
GeneTreeiENSGT00550000074954.
InParanoidiF1S2Q3.
KOiK20352.
OMAiFSMCCLI.
OrthoDBiEOG091G0O9D.
TreeFamiTF313729.

Family and domain databases

InterProiView protein in InterPro
IPR009038. GOLD_dom.
IPR015720. TMP21-related.
PANTHERiPTHR22811. PTHR22811. 1 hit.
PfamiView protein in Pfam
PF01105. EMP24_GP25L. 1 hit.
SMARTiView protein in SMART
SM01190. EMP24_GP25L. 1 hit.
PROSITEiView protein in PROSITE
PS50866. GOLD. 1 hit.

Sequencei

Sequence statusi: Complete.

F1S2Q3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGLSDPQAL RGPCPLALLL LFLLGPSSVL TISFHLPVNS RKCLREEIHK
60 70 80 90 100
DLLVTGAYEI TDQSGGAGGP RTHLKITDSA GHILYSKEDA TKGKFAFTTE
110 120 130 140 150
DYDMFEVCFE SKGTGRIPDQ LVILDMKHGV EAKNYEEIAK VEKLKPLEVE
160 170 180 190 200
LRRLEDLSES IVNDFAYMKK REEEMRDTNE STNTRVLYFS IFSMFCLIGL
210
ATWQVFYLRR FFKAKKLIE
Length:219
Mass (Da):24,911
Last modified:July 11, 2012 - v2
Checksum:iD47F4CD9B6E3C773
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT737372 Genomic DNA. No translation available.
RefSeqiXP_001926746.1. XM_001926711.4.
UniGeneiSsc.9761.

Genome annotation databases

EnsembliENSSSCT00000002649; ENSSSCP00000002582; ENSSSCG00000002382.
GeneIDi100158015.
KEGGissc:100158015.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiF1S2Q3_PIG
AccessioniPrimary (citable) accession number: F1S2Q3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 11, 2012
Last modified: June 7, 2017
This is version 47 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported