Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

F1RQI7 (F1RQI7_PIG) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length1253 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSSSCP00000004831

Ontologies

Keywords
   LigandATP-binding SAAS SAAS001609
Nucleotide-binding
   Molecular functionMotor protein
Myosin SAAS SAAS001609
   Technical term3D-structure PDB 4E7S PDB 4E7Z
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA damage response, signal transduction by p53 class mediator

Inferred from electronic annotation. Source: Ensembl

auditory receptor cell differentiation

Inferred from electronic annotation. Source: Ensembl

cellular response to electrical stimulus

Inferred from electronic annotation. Source: Ensembl

dendrite development

Inferred from electronic annotation. Source: Ensembl

endocytosis

Inferred from electronic annotation. Source: Ensembl

glutamate secretion

Inferred from electronic annotation. Source: Ensembl

inner ear morphogenesis

Inferred from electronic annotation. Source: Ensembl

locomotory behavior

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

protein targeting

Inferred from electronic annotation. Source: Ensembl

regulation of secretion

Inferred from electronic annotation. Source: Ensembl

regulation of synaptic plasticity

Inferred from electronic annotation. Source: Ensembl

sensory perception of sound

Inferred from electronic annotation. Source: Ensembl

synapse assembly

Inferred from electronic annotation. Source: Ensembl

synaptic transmission

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentDNA-directed RNA polymerase II, holoenzyme

Inferred from electronic annotation. Source: Ensembl

Golgi apparatus

Inferred from electronic annotation. Source: Ensembl

axon

Inferred from electronic annotation. Source: Ensembl

clathrin-coated endocytic vesicle

Inferred from electronic annotation. Source: Ensembl

filamentous actin

Inferred from electronic annotation. Source: Ensembl

myosin complex

Inferred from electronic annotation. Source: UniProtKB-KW

neuronal cell body

Inferred from electronic annotation. Source: Ensembl

nuclear membrane

Inferred from electronic annotation. Source: Ensembl

plasma membrane

Inferred from electronic annotation. Source: Ensembl

ruffle

Inferred from electronic annotation. Source: Ensembl

vesicle membrane

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

motor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding154 – 1596ADP PDB 4E7S PDB 4E7Z

Sites

Binding site981ADP PDB 4E7S PDB 4E7Z
Binding site1071ADP PDB 4E7S PDB 4E7Z
Binding site2001ADP PDB 4E7S PDB 4E7Z

Sequences

Sequence LengthMass (Da)Tools
F1RQI7 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 3CB3C2C720469A8B

FASTA1,253144,928
        10         20         30         40         50         60 
MEDGKPVWAP HPTDGFQVGN IVDIGPDSLT IEPLNQKGKT FLALINQVFP AEEDSKKDVE 

        70         80         90        100        110        120 
DNCSLMYLNE ATLLHNIKVR YSKDRIYTYV ANILIAVNPY FDIPKIYSSE TIKSYQGKSL 

       130        140        150        160        170        180 
GTMPPHVFAI ADKAFRDMKV LKLSQSIIVS GESGAGKTEN TKFVLRYLTE SYGTGQDIDD 

       190        200        210        220        230        240 
RIVEANPLLE AFGNAKTVRN NNSSRFGKFV EIHFNEKSSV VGGFVSHYLL EKSRICVQGK 

       250        260        270        280        290        300 
EERNYHIFYR LCAGASEDIR ERLHLSSPDN FRYLNRGCTR YFANKETDKQ ILQNRKSPEY 

       310        320        330        340        350        360 
LKAGSLKDPL LDDHGDFIRM CTAMKKIGLD DEEKLDLFRV VAGVLHLGNI DFEEAGSTSG 

       370        380        390        400        410        420 
GCNLKNKSTQ ALEYCAELLG LDQDDLRVSL TTRVMLTTAG GAKGTVIKVP LKVEQANNAR 

       430        440        450        460        470        480 
DALAKTVYSH LFDHVVNRVN QCFPFETSSY FIGVLDIAGF EYFEHNSFEQ FCINYCNEKL 

       490        500        510        520        530        540 
QQFFNERILK EEQELYQKEG LGVNEVHYVD NQDCIDLIEA RLVGILDILD EENRLPQPSD 

       550        560        570        580        590        600 
QHFTSAVHQK HKDHFRLSIP RKSKLAIHRN IRDDEGFIIR HFAGAVCYET TQFVEKNNDA 

       610        620        630        640        650        660 
LHMSLESLIC ESRDKFIREL FESSTNNNKD TKQKAGKLSF ISVGNKFKTQ LNLLLDKLRS 

       670        680        690        700        710        720 
TGASFIRCIK PNLKMTSHHF EGAQILSQLQ CSGMVSVLDL MQGGFPSRAS FHELYNMYKK 

       730        740        750        760        770        780 
YMPDKLARLD PRLFCKALFK ALGLNEIDYK FGLTKVFFRP GKFAEFDQIM KSDPDHLAEL 

       790        800        810        820        830        840 
VKRVNHWLIC SRWKKVQWCS LSVIKLKNKI KYRAEACIKM QKTIRMWLCK RRHKPRIDGL 

       850        860        870        880        890        900 
VKVGTLKKRL DKFNEVVSAL KDGKQEMSKQ VKDLEISIDA LMAKIKSTMM TREQIQKEYD 

       910        920        930        940        950        960 
ALVKSSAVLL SALQKKKQQE EEAERLRRIQ EEMEKERKRR EEDEQRRRKE EEERRMKLEM 

       970        980        990       1000       1010       1020 
EAKRKQEEEE RKKREDDEKR IQAEVEAQLA RQREEESQQQ AVLEQERRDR ELALRIAQSE 

      1030       1040       1050       1060       1070       1080 
AELISDEAQA DPGLRRGPAV QATKAAAGTK KYDLSKWKYA ELRDTINTSC DIELLAACRE 

      1090       1100       1110       1120       1130       1140 
EFHRRLKVYH AWKSKNKKRN TETEQRAPKS VTDYAQQNPA VQLPARQQEI EMNRQQRFFR 

      1150       1160       1170       1180       1190       1200 
IPFIRPADQY KDPQNKKKGW WYAHFDGPWI ARQMELHPDK PPILLVAGKD DMEMCELNLE 

      1210       1220       1230       1240       1250 
ETGLTRKRGA EILPRQFEEI WERCGGIQYL QNAIESRQAR PTYATAMLQN LLK 

« Hide

References

« Hide 'large scale' references
[1]Porcine genome sequencing project
Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (MAY-2011) to UniProtKB
Cited for: IDENTIFICATION.
[3]"Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI."
Menetrey J., Isabet T., Ropars V., Mukherjea M., Pylypenko O., Liu X., Perez J., Vachette P., Sweeney H.L., Houdusse A.M.
Mol. Cell 48:75-86(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS) OF 2-789 IN COMPLEX WITH ADP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU469475 Genomic DNA. No translation available.
RefSeqXP_005659486.1. XM_005659429.1.
XP_005659487.1. XM_005659430.1.
UniGeneSsc.94.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4E7SX-ray2.25A/B2-789[»]
4E7ZX-ray2.30A/B2-789[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSSSCT00000004948; ENSSSCP00000004831; ENSSSCG00000004478.
GeneID397085.
KEGGssc:397085.

Organism-specific databases

CTD4646.

Phylogenomic databases

GeneTreeENSGT00750000117545.
KOK10358.
OMARHKPRID.
OrthoDBEOG7TQTZZ.
TreeFamTF351449.

Family and domain databases

InterProIPR000048. IQ_motif_EF-hand-BS.
IPR001609. Myosin_head_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00063. Myosin_head. 1 hit.
[Graphical view]
PRINTSPR00193. MYOSINHEAVY.
SMARTSM00015. IQ. 1 hit.
SM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
ProtoNetSearch...

Entry information

Entry nameF1RQI7_PIG
AccessionPrimary (citable) accession number: F1RQI7
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 16, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)