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Protein
Submitted name:

Hexose-binding lectin 4

Gene

hbl4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-DRE-166662. Lectin pathway of complement activation.
R-DRE-166663. Initial triggering of complement.
R-DRE-5683826. Surfactant metabolism.
R-DRE-5686938. Regulation of TLR by endogenous ligand.

Names & Taxonomyi

Protein namesi
Submitted name:
Hexose-binding lectin 4Imported
Gene namesi
Name:hbl4Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-070912-287. hbl4.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500327077123 – 245Sequence analysisAdd BLAST223

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiF1RBU9.

Expressioni

Gene expression databases

BgeeiENSDARG00000054202.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000037076.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 244C-type lectinInterPro annotationAdd BLAST112

Keywords - Domaini

CollagenSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IS38. Eukaryota.
ENOG410YQHR. LUCA.
GeneTreeiENSGT00700000104102.
InParanoidiF1RBU9.
OMAiYSETVTC.
OrthoDBiEOG091G0R93.
TreeFamiTF330481.

Family and domain databases

CDDicd03591. CLECT_collectin_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR008160. Collagen.
IPR033990. Collectin_CTLD.
IPR016187. CTDL_fold.
PfamiView protein in Pfam
PF01391. Collagen. 1 hit.
PF00059. Lectin_C. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F1RBU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLKHQLCA VLLMMESGLI LSASESSCPS YAGVPGIPGN NGSPGRDGRD
60 70 80 90 100
GFPGPKGEKG DLGIGAQGPP GKIGPPGAPG HKGDRGSPGL SGTDVQNTLV
110 120 130 140 150
TQLRSDVKHL TDRLTVIDKV LGFRMFKKVG QKYYVSDGLV GNFETAQKFC
160 170 180 190 200
SDAGAKIVLP RSEDENKVLI SLQEALESTY VHVGATDAKK EGHFVDLSDQ
210 220 230 240
PLTFTNWKEK EPNDYNGAED CTAVYKTGVW NDINCNSKWH VVCEL
Length:245
Mass (Da):26,189
Last modified:May 3, 2011 - v1
Checksum:i88C3BE43ADD8FFAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954692 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000035685; ENSDARP00000037076; ENSDARG00000054202.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiF1RBU9_DANRE
AccessioniPrimary (citable) accession number: F1RBU9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 7, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported