Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

F1R9E8

- F1R9E8_DANRE

UniProt

F1R9E8 - F1R9E8_DANRE

Protein
Submitted name:

Uncharacterized protein

Gene

gad2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. carboxy-lyase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. gamma-aminobutyric acid biosynthetic process Source: ZFIN
    2. neurotransmitter biosynthetic process Source: ZFIN

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    ReactomeiREACT_207458. GABA synthesis, release, reuptake and degradation.
    REACT_223869. GABA synthesis.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:gad2Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Chromosome 24

    Organism-specific databases

    ZFINiZDB-GENE-030909-9. gad2.

    Expressioni

    Gene expression databases

    BgeeiF1R9E8.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00730000110441.
    KOiK01580.
    OMAiWRAKGTT.
    OrthoDBiEOG7H1JM3.
    TreeFamiTF314688.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F1R9E8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASHGFWFLG AENAAGNGSQ SPNTPRAWCQ AAAQKFSGGI GSKLCALLNV    50
    GEAEKAAQAP VKAEDESTAE SCGCNKPCNC SKATACFSDL YSTDLLPALD 100
    GDAKTMNFLQ EVVDILLAYI VESFDRSTKV IDFHYPNELL QRNNWELSDE 150
    PETLDDILIS CRATLKYAIK TAHPRYFNQL STGLDMVGLA ADWLTSTANT 200
    NMFTYEVAPV FVLLEYVTLK KMREIIGWQD GHGDGIFSPG GAISNMYAML 250
    LARYKMFPEV KEKGMSSVPR LVAFTSEHSH FSIKKGAAAL GIGTESVICI 300
    KADERGKMIP SDLERRIIEA KQKGYVPFFV SATAGTTVYG AFDPLIAIAD 350
    ICKKHDVWMH VDGAWGGSLL MSRKHRWKLN GVERANSMTW NPHKMMAVPL 400
    QCSALLVREE GLMQSCNQMQ ACYLFQQDKH YDLQYDTGDK ALQCGRHVDI 450
    FKLWLMWRAK GTIGFEAQID KCLELSEYLY NKIKDREGYQ MVFDGKPQHT 500
    NVCFWYLPPG VRYLEDKVER MKRLHKVAPV IKARMMEYGT TMVSYQPQGD 550
    KVNFFRMVIS NPAATFEDID FLIEEIERLG QDL 583
    Length:583
    Mass (Da):65,458
    Last modified:May 3, 2011 - v1
    Checksum:iCFEDA3A6F5BD51CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX530066 Genomic DNA. No translation available.
    CR855137 Genomic DNA. No translation available.
    RefSeqiNP_001017708.2. NM_001017708.2.
    UniGeneiDr.81033.

    Genome annotation databases

    EnsembliENSDART00000021609; ENSDARP00000010443; ENSDARG00000015537.
    GeneIDi550403.
    KEGGidre:550403.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX530066 Genomic DNA. No translation available.
    CR855137 Genomic DNA. No translation available.
    RefSeqi NP_001017708.2. NM_001017708.2.
    UniGenei Dr.81033.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSDART00000021609 ; ENSDARP00000010443 ; ENSDARG00000015537 .
    GeneIDi 550403.
    KEGGi dre:550403.

    Organism-specific databases

    CTDi 2572.
    ZFINi ZDB-GENE-030909-9. gad2.

    Phylogenomic databases

    GeneTreei ENSGT00730000110441.
    KOi K01580.
    OMAi WRAKGTT.
    OrthoDBi EOG7H1JM3.
    TreeFami TF314688.

    Enzyme and pathway databases

    Reactomei REACT_207458. GABA synthesis, release, reuptake and degradation.
    REACT_223869. GABA synthesis.

    Miscellaneous databases

    NextBioi 20879652.

    Gene expression databases

    Bgeei F1R9E8.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: TuebingenImported.
    2. "The zebrafish reference genome sequence and its relationship to the human genome."
      Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
      , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
      Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TuebingenImported.

    Entry informationi

    Entry nameiF1R9E8_DANRE
    AccessioniPrimary (citable) accession number: F1R9E8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3