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Protein

Mannosyltransferase

Gene

alg12

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-DRE-446193. Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein.

Names & Taxonomyi

Protein namesi
Recommended name:
MannosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:alg12Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 4

Organism-specific databases

ZFINiZDB-GENE-041210-295. alg12.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalUniRule annotationAdd BLAST20
Transmembranei67 – 87HelicalUniRule annotationAdd BLAST21
Transmembranei96 – 114HelicalUniRule annotationAdd BLAST19
Transmembranei120 – 139HelicalUniRule annotationAdd BLAST20
Transmembranei146 – 165HelicalUniRule annotationAdd BLAST20
Transmembranei171 – 196HelicalUniRule annotationAdd BLAST26
Transmembranei208 – 226HelicalUniRule annotationAdd BLAST19
Transmembranei259 – 283HelicalUniRule annotationAdd BLAST25
Transmembranei290 – 305HelicalUniRule annotationAdd BLAST16
Transmembranei311 – 331HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1R725.

Expressioni

Gene expression databases

BgeeiENSDARG00000041199.
ExpressionAtlasiF1R725. baseline.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000104056.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 22 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2516. Eukaryota.
ENOG410XR38. LUCA.
GeneTreeiENSGT00550000075005.
InParanoidiF1R725.
TreeFamiTF314453.

Family and domain databases

InterProiView protein in InterPro
IPR005599. GPI_mannosylTrfase.
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiView protein in Pfam
PF03901. Glyco_transf_22. 1 hit.

Sequencei

Sequence statusi: Complete.

F1R725-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARKEAVNES CLLIFMISIS LLHLFTCPYT KVEESFNLQA IHDILYHRFD
60 70 80 90 100
FEKYDHHEFP GVVPRTFLGP LVISALSAPM TCVLVLFQAP KFYTQILVRG
110 120 130 140 150
VLGLCVILSL WLMQKEVRRQ FGSLVASLFC FICTTQFHLM FYITRTLPNV
160 170 180 190 200
FALPLVLLAF TSWLAQRHGA FIWLSALAAI VFRSELCLFF GLMLLMSLLN
210 220 230 240 250
RKLNFGQLLY HAIPAGFVSL GLTIMFDSLF WNKLLWPEGQ VLWYNTVLNK
260 270 280 290 300
SSNWGTSPFL WYFYSALPRA LASTILFIPL GLLDRRTRKL LVVSIGFILL
310 320 330 340 350
YSLLPHKELR FIIYTFPVFN VIGACGCSFI LKNYQKSRIY KIGSIVVVGH
360 370 380 390 400
LMLNATYTSI SLYVSHHNYP GGKAMQELHR LMPTTADVSL HIDVLAAQTG
410 420 430 440 450
VSRFLELNSN WRYDKKEDLT VEDPVMKTYS HLLMEVNATK ILLLKDSHKP
460 470 480 490
LVFITGYQSL TFEMFHFPPL KIQLNKKLVL LERQSNKVNG GLN
Length:493
Mass (Da):56,504
Last modified:May 3, 2011 - v1
Checksum:iDF11291CAB607143
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR751234 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000115200; ENSDARP00000104056; ENSDARG00000041199.

Similar proteinsi

Entry informationi

Entry nameiF1R725_DANRE
AccessioniPrimary (citable) accession number: F1R725
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 15, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported