F1R0G2 (F1R0G2_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSDARP00000107492 Ensembl ENSDARP00000005106

Gene names

Name:

mre11a Ensembl ENSDARP00000107492 Ensembl ENSDARP00000005106 ZFIN ZDB-GENE-040426-2638

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome] Ensembl ENSDARP00000005106

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	619 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the MRE11/RAD32 family. RuleBase RU003447
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSDARP00000107492 Ensembl ENSDARP00000005106

Ontologies

Keywords
Biological process	DNA damage DNA repair RuleBase RU003447 Meiosis RuleBase RU003447
Cellular component	Nucleus RuleBase RU003447
Ligand	Manganese RuleBase RU003447
Molecular function	Endonuclease RuleBase RU003447 Exonuclease RuleBase RU003447 Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	double-strand break repair Inferred from electronic annotation. Source: InterPro meiosis Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW exonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW manganese ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1R0G2 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 882752748DB762FD	FASTA	619	70,459
	10 20 30 40 50 60 MASAGSTVDD EDTFKILIAT DIHLGYLEKD AIRGNDTFVT FDEIMKQAMQ NEVDFVLLGG 70 80 90 100 110 120 DLFHDNKPSR KTMHSCMEVM RKYCMGDRPI IFEIISDQAV NFSHSRFPWV NYLDDNLNIS 130 140 150 160 170 180 IPIFSVHGNH DDPTGSDGLC AVDLLSCAGL VNHFGRSRSV EKVEISPVLL QKGDTRIALY 190 200 210 220 230 240 GLGSIPDERL YRMFVNNQVT MLRPREDEDG WFNLFVIHQN RSKHGATNYI PEQFLDDFLD 250 260 270 280 290 300 LVVWGHEHEC KIAPVRNEQQ LFYVTQPGSS VITSLSPGEA VKKHIGLLRV KGKKMNLQKI 310 320 330 340 350 360 PLQTVRQFFI QDVVLSDYPE LFSPEQPNTM LKVQAFCQEK VEEMLEEAER ERLGNPQIPE 370 380 390 400 410 420 KPLIRLRVDY SGGFEVFNTM RFSQKFVDKV ANPKDILHFV RHRETKGNIK DEDVDFEALF 430 440 450 460 470 480 SRPTSEVLQL RVEDLVKEYF QTAEKNVQLS LLTEQGMGKA VQEFVDKEER DAIEELINYQ 490 500 510 520 530 540 LEKTQRYLRE RRVDATEEKI DEEIRQFRDS KRNTAEEDEE VQEAIIRAKA HRDRGETARD 550 560 570 580 590 600 DDLGLSDDPA DIAMESDEEP SSAPPVRGRG RGSRGGRDPC ASKRGRARGA ASRSGRGGRG 610 RGSLSSPVKT KSIMDGCLH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000107492 Ensembl ENSDARP00000005106.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000005106.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000107492.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CABZ01086029 Genomic DNA. No translation available. CABZ01086030 Genomic DNA. No translation available. CABZ01086031 Genomic DNA. No translation available. CABZ01086032 Genomic DNA. No translation available. CABZ01086033 Genomic DNA. No translation available. CABZ01086034 Genomic DNA. No translation available. CABZ01086035 Genomic DNA. No translation available. CABZ01086036 Genomic DNA. No translation available. CABZ01086037 Genomic DNA. No translation available. CABZ01086038 Genomic DNA. No translation available. CU914486 Genomic DNA. No translation available.
IPI	IPI00509459.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000004840; ENSDARP00000005106; ENSDARG00000006394. ENSDART00000128572; ENSDARP00000107492; ENSDARG00000006394.
Organism-specific databases
ZFIN	ZDB-GENE-040426-2638. mre11a.
Phylogenomic databases
GeneTree	ENSGT00390000017288.
Family and domain databases
InterPro	IPR003701. DNA_repair_Mre11. IPR004843. Metallo_PEstase_dom. IPR007281. Mre11_DNA-bd. [Graphical view]
PANTHER	PTHR10139. PTHR10139. 1 hit.
Pfam	PF00149. Metallophos. 1 hit. PF04152. Mre11_DNA_bind. 1 hit. [Graphical view]
PIRSF	PIRSF000882. DSB_repair_MRE11. 1 hit.
TIGRFAMs	TIGR00583. mre11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F1R0G2_DANRE

Accession

Primary (citable) accession number: F1R0G2

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	January 9, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)