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Protein
Submitted name:

Complement component 7a

Gene

c7a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-166665 Terminal pathway of complement
R-DRE-977606 Regulation of Complement cascade

Names & Taxonomyi

Protein namesi
Submitted name:
Complement component 7aImported
Gene namesi
Name:c7aImported
Synonyms:si:dkey-250l23.2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 8

Organism-specific databases

ZFINiZDB-GENE-081104-392 c7a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi120 ↔ 138PROSITE-ProRule annotation
Disulfide bondi132 ↔ 147PROSITE-ProRule annotation
Disulfide bondi623 ↔ 650PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiF1QM47

Expressioni

Gene expression databases

BgeeiENSDARG00000042172
ExpressionAtlasiF1QM47 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000118698

Structurei

3D structure databases

ProteinModelPortaliF1QM47
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 480MACPFInterPro annotationAdd BLAST327
Domaini593 – 652SushiInterPro annotationAdd BLAST60
Domaini653 – 714SushiInterPro annotationAdd BLAST62

Keywords - Domaini

SushiPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IDXP Eukaryota
ENOG410YJ70 LUCA
GeneTreeiENSGT00550000074478
InParanoidiF1QM47
OMAiGKCVCKM
OrthoDBiEOG091G07LK
TreeFamiTF330498

Family and domain databases

CDDicd00033 CCP, 2 hits
cd00112 LDLa, 1 hit
Gene3Di2.20.100.10, 2 hits
InterProiView protein in InterPro
IPR037564 Complement_C7
IPR003884 FacI_MAC
IPR036055 LDL_receptor-like_sf
IPR023415 LDLR_class-A_CS
IPR002172 LDrepeatLR_classA_rpt
IPR001862 MAC_perforin
IPR020864 MACPF
IPR020863 MACPF_CS
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
PANTHERiPTHR19325:SF389 PTHR19325:SF389, 1 hit
PfamiView protein in Pfam
PF00057 Ldl_recept_a, 1 hit
PF01823 MACPF, 1 hit
PF00084 Sushi, 2 hits
PF00090 TSP_1, 2 hits
PRINTSiPR00764 COMPLEMENTC9
SMARTiView protein in SMART
SM00032 CCP, 2 hits
SM00057 FIMAC, 2 hits
SM00192 LDLa, 1 hit
SM00457 MACPF, 1 hit
SM00209 TSP1, 2 hits
SUPFAMiSSF57424 SSF57424, 1 hit
SSF57535 SSF57535, 2 hits
SSF82895 SSF82895, 2 hits
PROSITEiView protein in PROSITE
PS01209 LDLRA_1, 1 hit
PS50068 LDLRA_2, 1 hit
PS00279 MACPF_1, 1 hit
PS51412 MACPF_2, 1 hit
PS50923 SUSHI, 2 hits
PS50092 TSP1, 2 hits

Sequencei

Sequence statusi: Fragment.

F1QM47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XLYRQTACRE MCVLLQIATM KCVFLHGVFL LSLLSSAPIT HAGSLRSIRS
60 70 80 90 100
ASEPVHCLWG SWSSWSACDR CSKTQTQIRF VAVFSQFGGQ PCTGSSTRTQ
110 120 130 140 150
TCISTQVCPL EEGCGGRFRC QSGKCISLSL VCNSDQDCED GSDEQRCDSK
160 170 180 190 200
PICKISENTN LQKPPPNVEI TGQGFDAAKR EARGTVINTK SFGGLCQKTF
210 220 230 240 250
SGDHKDFYRL PQSVLSYSFQ VTAKNDFTDE SFASSWHYLH HYEKHEKTTG
260 270 280 290 300
TDYGHDDYVF HDELSQSKSK NLMIIKSDVE VGQFKNKDPE YLPLSEDFWK
310 320 330 340 350
ALVALPVVYD YAAYRNVLER FGTHYISEGS LGGHFKLYLM ASEDVISKLK
360 370 380 390 400
SEKRDYEDCV VTSHSVMFFI RWSTKTCKTD TIDETKTFYK SIPESDMKTD
410 420 430 440 450
IIGGDPGFIA KLSMFYKYDV KENARTFSQW SGSLKYYPRI IKSKLRSLHE
460 470 480 490 500
LVKEVPCAGL KRFLLKRAIE TYLTEKHSCQ CRECQNNGLR VLDGNVCKCV
510 520 530 540 550
CKPGTSGQAC EYGTAYDEQP GVIHGDWACW SSWSSCSGGQ KSRRRSCTRP
560 570 580 590 600
APSGGRDCIG NTEERTACED EEELNHLRSM EPHCFDDSIK PRESCKTPPF
610 620 630 640 650
VPNGFVLYPK DVYPVGSKIE YTCIEGYHLI GNAIAKCQED LNWLQYPVEC
660 670 680 690 700
KKTQCDPPQL PPDVTANPWK LNYNIGEAIA LSCPEGKVKE GLDEIQCNAG
710 720 730 740 750
LSWSPQPKNT KCLTAVLKPT VVPVKCQPWE NLAKDKCVCK VPHQCKSSLE
760 770 780 790 800
VCVTDEKRGR TQRLSVCKVQ AMRCLGHQYS LAEDSACQWT QPSTNNCTRC
810 820 830 840 850
TLGETCDEQT NSCRCKTSED CSSPDTWIHV CVKQDKASAP VTMTECEVAM
860
RKCRGETVHI VSIQACQS
Length:868
Mass (Da):97,348
Last modified:May 3, 2011 - v1
Checksum:i7EB1AC082EF815BC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571721 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000146933; ENSDARP00000118698; ENSDARG00000042172

Similar proteinsi

Entry informationi

Entry nameiF1QM47_DANRE
AccessioniPrimary (citable) accession number: F1QM47
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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