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Protein
Submitted name:

Complement component 7a

Gene

c7a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-166665. Terminal pathway of complement.
R-DRE-977606. Regulation of Complement cascade.

Names & Taxonomyi

Protein namesi
Submitted name:
Complement component 7aImported
Gene namesi
Name:c7aImported
Synonyms:si:dkey-250l23.2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 8

Organism-specific databases

ZFINiZDB-GENE-081104-392. c7a.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi120 ↔ 138PROSITE-ProRule annotation
Disulfide bondi132 ↔ 147PROSITE-ProRule annotation
Disulfide bondi623 ↔ 650PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiF1QM47.

Expressioni

Gene expression databases

ExpressionAtlasiF1QM47. baseline.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000118698.

Structurei

3D structure databases

ProteinModelPortaliF1QM47.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 480MACPFInterPro annotationAdd BLAST327
Domaini593 – 652Sushi (CCP/SCR)InterPro annotationAdd BLAST60
Domaini653 – 714Sushi (CCP/SCR)InterPro annotationAdd BLAST62

Keywords - Domaini

SushiPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IDXP. Eukaryota.
ENOG410YJ70. LUCA.
GeneTreeiENSGT00550000074478.
InParanoidiF1QM47.
OMAiGKCVCKM.
OrthoDBiEOG091G07LK.
TreeFamiTF330498.

Family and domain databases

CDDicd00033. CCP. 2 hits.
Gene3Di2.20.100.10. 1 hit.
3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR016186. C-type_lectin-like/link.
IPR003884. FacI_MAC.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR001862. MAC_perforin.
IPR020864. MACPF.
IPR020863. MACPF_CS.
IPR000436. Sushi_SCR_CCP_dom.
IPR000884. TSP1_rpt.
PfamiView protein in Pfam
PF00057. Ldl_recept_a. 1 hit.
PF01823. MACPF. 1 hit.
PF00084. Sushi. 2 hits.
PF00090. TSP_1. 2 hits.
PRINTSiPR00764. COMPLEMENTC9.
SMARTiView protein in SMART
SM00032. CCP. 2 hits.
SM00057. FIMAC. 2 hits.
SM00192. LDLa. 1 hit.
SM00457. MACPF. 1 hit.
SM00209. TSP1. 2 hits.
SUPFAMiSSF57424. SSF57424. 1 hit.
SSF57535. SSF57535. 2 hits.
SSF82895. SSF82895. 2 hits.
PROSITEiView protein in PROSITE
PS01209. LDLRA_1. 1 hit.
PS50068. LDLRA_2. 1 hit.
PS00279. MACPF_1. 1 hit.
PS51412. MACPF_2. 1 hit.
PS50923. SUSHI. 2 hits.
PS50092. TSP1. 2 hits.

Sequencei

Sequence statusi: Fragment.

F1QM47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XLYRQTACRE MCVLLQIATM KCVFLHGVFL LSLLSSAPIT HAGSLRSIRS
60 70 80 90 100
ASEPVHCLWG SWSSWSACDR CSKTQTQIRF VAVFSQFGGQ PCTGSSTRTQ
110 120 130 140 150
TCISTQVCPL EEGCGGRFRC QSGKCISLSL VCNSDQDCED GSDEQRCDSK
160 170 180 190 200
PICKISENTN LQKPPPNVEI TGQGFDAAKR EARGTVINTK SFGGLCQKTF
210 220 230 240 250
SGDHKDFYRL PQSVLSYSFQ VTAKNDFTDE SFASSWHYLH HYEKHEKTTG
260 270 280 290 300
TDYGHDDYVF HDELSQSKSK NLMIIKSDVE VGQFKNKDPE YLPLSEDFWK
310 320 330 340 350
ALVALPVVYD YAAYRNVLER FGTHYISEGS LGGHFKLYLM ASEDVISKLK
360 370 380 390 400
SEKRDYEDCV VTSHSVMFFI RWSTKTCKTD TIDETKTFYK SIPESDMKTD
410 420 430 440 450
IIGGDPGFIA KLSMFYKYDV KENARTFSQW SGSLKYYPRI IKSKLRSLHE
460 470 480 490 500
LVKEVPCAGL KRFLLKRAIE TYLTEKHSCQ CRECQNNGLR VLDGNVCKCV
510 520 530 540 550
CKPGTSGQAC EYGTAYDEQP GVIHGDWACW SSWSSCSGGQ KSRRRSCTRP
560 570 580 590 600
APSGGRDCIG NTEERTACED EEELNHLRSM EPHCFDDSIK PRESCKTPPF
610 620 630 640 650
VPNGFVLYPK DVYPVGSKIE YTCIEGYHLI GNAIAKCQED LNWLQYPVEC
660 670 680 690 700
KKTQCDPPQL PPDVTANPWK LNYNIGEAIA LSCPEGKVKE GLDEIQCNAG
710 720 730 740 750
LSWSPQPKNT KCLTAVLKPT VVPVKCQPWE NLAKDKCVCK VPHQCKSSLE
760 770 780 790 800
VCVTDEKRGR TQRLSVCKVQ AMRCLGHQYS LAEDSACQWT QPSTNNCTRC
810 820 830 840 850
TLGETCDEQT NSCRCKTSED CSSPDTWIHV CVKQDKASAP VTMTECEVAM
860
RKCRGETVHI VSIQACQS
Length:868
Mass (Da):97,348
Last modified:May 3, 2011 - v1
Checksum:i7EB1AC082EF815BC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571721 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000146933; ENSDARP00000118698; ENSDARG00000042172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571721 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF1QM47.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000118698.

Proteomic databases

PaxDbiF1QM47.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000146933; ENSDARP00000118698; ENSDARG00000042172.

Organism-specific databases

ZFINiZDB-GENE-081104-392. c7a.

Phylogenomic databases

eggNOGiENOG410IDXP. Eukaryota.
ENOG410YJ70. LUCA.
GeneTreeiENSGT00550000074478.
InParanoidiF1QM47.
OMAiGKCVCKM.
OrthoDBiEOG091G07LK.
TreeFamiTF330498.

Enzyme and pathway databases

ReactomeiR-DRE-166665. Terminal pathway of complement.
R-DRE-977606. Regulation of Complement cascade.

Gene expression databases

ExpressionAtlasiF1QM47. baseline.

Family and domain databases

CDDicd00033. CCP. 2 hits.
Gene3Di2.20.100.10. 1 hit.
3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR016186. C-type_lectin-like/link.
IPR003884. FacI_MAC.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR001862. MAC_perforin.
IPR020864. MACPF.
IPR020863. MACPF_CS.
IPR000436. Sushi_SCR_CCP_dom.
IPR000884. TSP1_rpt.
PfamiView protein in Pfam
PF00057. Ldl_recept_a. 1 hit.
PF01823. MACPF. 1 hit.
PF00084. Sushi. 2 hits.
PF00090. TSP_1. 2 hits.
PRINTSiPR00764. COMPLEMENTC9.
SMARTiView protein in SMART
SM00032. CCP. 2 hits.
SM00057. FIMAC. 2 hits.
SM00192. LDLa. 1 hit.
SM00457. MACPF. 1 hit.
SM00209. TSP1. 2 hits.
SUPFAMiSSF57424. SSF57424. 1 hit.
SSF57535. SSF57535. 2 hits.
SSF82895. SSF82895. 2 hits.
PROSITEiView protein in PROSITE
PS01209. LDLRA_1. 1 hit.
PS50068. LDLRA_2. 1 hit.
PS00279. MACPF_1. 1 hit.
PS51412. MACPF_2. 1 hit.
PS50923. SUSHI. 2 hits.
PS50092. TSP1. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiF1QM47_DANRE
AccessioniPrimary (citable) accession number: F1QM47
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 10, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.