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F1QA79

- F1QA79_DANRE

UniProt

F1QA79 - F1QA79_DANRE

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Protein
Submitted name:

Uncharacterized protein

Gene

nsd1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

Metal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:nsd1aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 14

Organism-specific databases

ZFINiZDB-GENE-080519-3. nsd1a.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiF1QA79.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118855.
InParanoidiF1QA79.
KOiK15588.
TreeFamiTF329088.

Family and domain databases

Gene3Di3.30.40.10. 3 hits.
InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 2 hits.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00570. AWS. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 2 hits.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 3 hits.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1QA79-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNQSYKVAGR DGSECRGDPQ DSRALDVRIG SCGQQSTKAD QSSAMHFLNP
60 70 80 90 100
GYKLSAPFAY NQRESTSNYS PLRRLQDLTT MVNHADGGLQ DKDFHGRNKL
110 120 130 140 150
LMHSPIGGNE FGIGLYNTTN SQGNTAIQDL DKNGFSPVSS DSLEHFSPIS
160 170 180 190 200
NGFLHFDSTL FDSGDSKDND EDVKGEVATF KDTSKKCQKR NVAKTETQSS
210 220 230 240 250
HRLDANKHSS KNTAKSDPPA SPFHVPFTMM EDFDSMDDYS DSDCDLPSTE
260 270 280 290 300
NCASIFNLSK RAHSPSDSHS NPSSSPKKKQ LLSVKYSIGD VVWAKFNRRP
310 320 330 340 350
WWPCHVTTDP QIDVHTKMKD PSRRPCRLYF VRMFGEIVDQ AWVPAKATFP
360 370 380 390 400
FEGGDQFEKL PVLRRRGRQK EKDYKYTVPK RLIPSWKASV LEAEASLTKQ
410 420 430 440 450
LNSEPPLTLI QDVCVPITED KAHKKNPACP KSTTLSTPSS SLLSNGLNAS
460 470 480 490 500
VKNRLKPGTA SKKKATKKMI QSQSIKLSET PSLFKSKSNP SSDKPSIATD
510 520 530 540 550
PLDSPYSDID SVPRILCSKR IDESLQVELE KELSTKTTKV QACKKTSKNS
560 570 580 590 600
VDKPGKKTDV KCLKNSKLKK STPKDKTLKA TSSRLKESSS PGSSDGSFAM
610 620 630 640 650
HSHYLPASSG LIVRALAAGE ETKEKDLSHE PNSHSPSSEH SSQTNHELSK
660 670 680 690 700
QNWEVKNNSE SSEESVDASD SPPNPTSIKR IKKRPQKNGI HKDPPPKSHE
710 720 730 740 750
ESESKVNNES MFSDTSSSSI PSPSISPMDA FQDIKELSFR SLVKEECSSG
760 770 780 790 800
ESPLRADSNY KFSTFLMLLK DLHDSREKEG KPLTLPPTSP SSLIKEEPSL
810 820 830 840 850
IPVGEEPPNE VLCEKEFAEQ SSLPGKTSTP NNSKQSKAKL KSTVKKESQK
860 870 880 890 900
PDVVIDSVSP LKKPISPVGL DVLDKSLPLL GDLPKSSDVS AAVTDVCAKG
910 920 930 940 950
TISKVAPKKR WKTFESELGK SIKPKSDQVD STLDEVKSVS TEPNGVFKDG
960 970 980 990 1000
LQESAHSDVP NKKDASENKR LRKPSKRLIE CGEEYEQIFP SKKKTKKSTE
1010 1020 1030 1040 1050
SCKTGSCISN TTPEQPASDQ ITLDAVSSSS AEKPLDHVVA EEQKPPADVL
1060 1070 1080 1090 1100
VPPSAPKSPS CATSLETEPC EKKSAPLERK RPRKSVHKVL DCAIEGESVK
1110 1120 1130 1140 1150
IPKKGESRQH KTNPEESGVR DLEKQEEAGP PPSSPCAVSA QSEGELRTSS
1160 1170 1180 1190 1200
PIQPDVPSVS QIPVEGEQSS PSKPQINNED SLISEGFAAG LNDSAFSSRD
1210 1220 1230 1240 1250
SLSGDLSGLS TNKRSVERGG GASLKENVCQ VCEKTGELLL CEGQCCGAFH
1260 1270 1280 1290 1300
LQCIGLTETP KGRFICQECK MGVHTCFVCK KPDKEVRRCM IPVCGKFYHM
1310 1320 1330 1340 1350
DCILKYSPTV AQNRGFRCSI HVCLSCYITN PNNPGISKGR LTRCVRCPVA
1360 1370 1380 1390 1400
YHANDYCMAA GSVPLANNSF LCPNHFTPRK GCKNHEHINV SWCFVCSEGG
1410 1420 1430 1440 1450
SLLCCESCPA AFHRECLNIE MPQGSWFCND CRAGKKPHYK DILWVKVGRY
1460 1470 1480 1490 1500
RWWPAEVTQP KSVPENISRM KHEVGEFPVH FFGSKDYVWT YQARCFPYME
1510 1520 1530 1540 1550
GDANNKEKMG KGADAVYKKA LNEAADRFRE LLKEKEMRQL QEDRKNDKKP
1560 1570 1580 1590 1600
PPYKHIKVNK QIGKVLIITA DLSEIPRCNC KATDENPCGI DSECINRMLL
1610 1620 1630 1640 1650
YECHSQVCPA GERCQNQSFT KRQYTEVEIF RTLSRGWGLR SISDIKKGAF
1660 1670 1680 1690 1700
VNEYVGEVID EEECRSRIKN AQDNDICNFY MLTLDKDRII DAGPKGNESR
1710 1720 1730 1740 1750
FMNHSCQPNC ETQKWTVNGD TRVGLFALED IPKGVELTFN YNLECLGNGK
1760 1770 1780 1790 1800
TVCKCGAPNC SGFLGVRPKN QPPSDDKTRK LRRKVSGKRK SQSEVTKERE
1810 1820 1830 1840 1850
DECFYCGDGG QIVSCKKPGC PKVYHADCLN LSKRPAGRWE CPWHQCNECG
1860 1870 1880 1890 1900
REAASYCEMC PNSYCEQHRE GMLFISKLDG KLSCSEHDPC GPDPLEPGEI
1910 1920 1930 1940 1950
REYVPSTSIV GQAPNMSASG RITQPALPPA APLFIPAQNR PAFQSQRDPY
1960 1970 1980 1990 2000
GDEVVDNILP SSSPKDIKEE DMSDGEVVFE EGEEEEEDLE LVDDEDDEEE
2010 2020 2030 2040 2050
IDCRGMGLED EEEEEEFEDY EDDFVNVDFV GTEDGDEVEG DEQETSWDEL

VEAEK
Length:2,055
Mass (Da):227,772
Last modified:May 3, 2011 - v1
Checksum:iFC5206F7F0DBDA1A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU633762 Genomic DNA. No translation available.
CU655965 Genomic DNA. No translation available.
CU659412 Genomic DNA. No translation available.
RefSeqiXP_683890.4. XM_678798.5.
UniGeneiDr.83733.

Genome annotation databases

EnsembliENSDART00000084114; ENSDARP00000078549; ENSDARG00000060016.
GeneIDi556086.
KEGGidre:556086.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU633762 Genomic DNA. No translation available.
CU655965 Genomic DNA. No translation available.
CU659412 Genomic DNA. No translation available.
RefSeqi XP_683890.4. XM_678798.5.
UniGenei Dr.83733.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000084114 ; ENSDARP00000078549 ; ENSDARG00000060016 .
GeneIDi 556086.
KEGGi dre:556086.

Organism-specific databases

CTDi 556086.
ZFINi ZDB-GENE-080519-3. nsd1a.

Phylogenomic databases

GeneTreei ENSGT00760000118855.
InParanoidi F1QA79.
KOi K15588.
TreeFami TF329088.

Miscellaneous databases

NextBioi 20881309.
PROi F1QA79.

Gene expression databases

Bgeei F1QA79.

Family and domain databases

Gene3Di 3.30.40.10. 3 hits.
InterProi IPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF00628. PHD. 2 hits.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00570. AWS. 1 hit.
SM00249. PHD. 4 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 2 hits.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF57903. SSF57903. 3 hits.
PROSITEi PS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiF1QA79_DANRE
AccessioniPrimary (citable) accession number: F1QA79
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3