F1QA79 (F1QA79_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSDARP00000078549

Gene names

Name:

nsd1a Ensembl ENSDARP00000078549 ZFIN ZDB-GENE-080519-3

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome] Ensembl ENSDARP00000078549

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	2055 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 post-SET domain. RuleBase RU004541
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSDARP00000078549

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Molecular function	Methyltransferase SAAS SAAS001214 RuleBase RU004541 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1QA79 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: FC5206F7F0DBDA1A	FASTA	2,055	227,772
	10 20 30 40 50 60 MNQSYKVAGR DGSECRGDPQ DSRALDVRIG SCGQQSTKAD QSSAMHFLNP GYKLSAPFAY 70 80 90 100 110 120 NQRESTSNYS PLRRLQDLTT MVNHADGGLQ DKDFHGRNKL LMHSPIGGNE FGIGLYNTTN 130 140 150 160 170 180 SQGNTAIQDL DKNGFSPVSS DSLEHFSPIS NGFLHFDSTL FDSGDSKDND EDVKGEVATF 190 200 210 220 230 240 KDTSKKCQKR NVAKTETQSS HRLDANKHSS KNTAKSDPPA SPFHVPFTMM EDFDSMDDYS 250 260 270 280 290 300 DSDCDLPSTE NCASIFNLSK RAHSPSDSHS NPSSSPKKKQ LLSVKYSIGD VVWAKFNRRP 310 320 330 340 350 360 WWPCHVTTDP QIDVHTKMKD PSRRPCRLYF VRMFGEIVDQ AWVPAKATFP FEGGDQFEKL 370 380 390 400 410 420 PVLRRRGRQK EKDYKYTVPK RLIPSWKASV LEAEASLTKQ LNSEPPLTLI QDVCVPITED 430 440 450 460 470 480 KAHKKNPACP KSTTLSTPSS SLLSNGLNAS VKNRLKPGTA SKKKATKKMI QSQSIKLSET 490 500 510 520 530 540 PSLFKSKSNP SSDKPSIATD PLDSPYSDID SVPRILCSKR IDESLQVELE KELSTKTTKV 550 560 570 580 590 600 QACKKTSKNS VDKPGKKTDV KCLKNSKLKK STPKDKTLKA TSSRLKESSS PGSSDGSFAM 610 620 630 640 650 660 HSHYLPASSG LIVRALAAGE ETKEKDLSHE PNSHSPSSEH SSQTNHELSK QNWEVKNNSE 670 680 690 700 710 720 SSEESVDASD SPPNPTSIKR IKKRPQKNGI HKDPPPKSHE ESESKVNNES MFSDTSSSSI 730 740 750 760 770 780 PSPSISPMDA FQDIKELSFR SLVKEECSSG ESPLRADSNY KFSTFLMLLK DLHDSREKEG 790 800 810 820 830 840 KPLTLPPTSP SSLIKEEPSL IPVGEEPPNE VLCEKEFAEQ SSLPGKTSTP NNSKQSKAKL 850 860 870 880 890 900 KSTVKKESQK PDVVIDSVSP LKKPISPVGL DVLDKSLPLL GDLPKSSDVS AAVTDVCAKG 910 920 930 940 950 960 TISKVAPKKR WKTFESELGK SIKPKSDQVD STLDEVKSVS TEPNGVFKDG LQESAHSDVP 970 980 990 1000 1010 1020 NKKDASENKR LRKPSKRLIE CGEEYEQIFP SKKKTKKSTE SCKTGSCISN TTPEQPASDQ 1030 1040 1050 1060 1070 1080 ITLDAVSSSS AEKPLDHVVA EEQKPPADVL VPPSAPKSPS CATSLETEPC EKKSAPLERK 1090 1100 1110 1120 1130 1140 RPRKSVHKVL DCAIEGESVK IPKKGESRQH KTNPEESGVR DLEKQEEAGP PPSSPCAVSA 1150 1160 1170 1180 1190 1200 QSEGELRTSS PIQPDVPSVS QIPVEGEQSS PSKPQINNED SLISEGFAAG LNDSAFSSRD 1210 1220 1230 1240 1250 1260 SLSGDLSGLS TNKRSVERGG GASLKENVCQ VCEKTGELLL CEGQCCGAFH LQCIGLTETP 1270 1280 1290 1300 1310 1320 KGRFICQECK MGVHTCFVCK KPDKEVRRCM IPVCGKFYHM DCILKYSPTV AQNRGFRCSI 1330 1340 1350 1360 1370 1380 HVCLSCYITN PNNPGISKGR LTRCVRCPVA YHANDYCMAA GSVPLANNSF LCPNHFTPRK 1390 1400 1410 1420 1430 1440 GCKNHEHINV SWCFVCSEGG SLLCCESCPA AFHRECLNIE MPQGSWFCND CRAGKKPHYK 1450 1460 1470 1480 1490 1500 DILWVKVGRY RWWPAEVTQP KSVPENISRM KHEVGEFPVH FFGSKDYVWT YQARCFPYME 1510 1520 1530 1540 1550 1560 GDANNKEKMG KGADAVYKKA LNEAADRFRE LLKEKEMRQL QEDRKNDKKP PPYKHIKVNK 1570 1580 1590 1600 1610 1620 QIGKVLIITA DLSEIPRCNC KATDENPCGI DSECINRMLL YECHSQVCPA GERCQNQSFT 1630 1640 1650 1660 1670 1680 KRQYTEVEIF RTLSRGWGLR SISDIKKGAF VNEYVGEVID EEECRSRIKN AQDNDICNFY 1690 1700 1710 1720 1730 1740 MLTLDKDRII DAGPKGNESR FMNHSCQPNC ETQKWTVNGD TRVGLFALED IPKGVELTFN 1750 1760 1770 1780 1790 1800 YNLECLGNGK TVCKCGAPNC SGFLGVRPKN QPPSDDKTRK LRRKVSGKRK SQSEVTKERE 1810 1820 1830 1840 1850 1860 DECFYCGDGG QIVSCKKPGC PKVYHADCLN LSKRPAGRWE CPWHQCNECG REAASYCEMC 1870 1880 1890 1900 1910 1920 PNSYCEQHRE GMLFISKLDG KLSCSEHDPC GPDPLEPGEI REYVPSTSIV GQAPNMSASG 1930 1940 1950 1960 1970 1980 RITQPALPPA APLFIPAQNR PAFQSQRDPY GDEVVDNILP SSSPKDIKEE DMSDGEVVFE 1990 2000 2010 2020 2030 2040 EGEEEEEDLE LVDDEDDEEE IDCRGMGLED EEEEEEFEDY EDDFVNVDFV GTEDGDEVEG 2050 DEQETSWDEL VEAEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000078549.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000078549.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU633762 Genomic DNA. No translation available. CU655965 Genomic DNA. No translation available. CU659412 Genomic DNA. No translation available.
IPI	IPI00512787.
RefSeq	XP_683890.4. XM_678798.4.
UniGene	Dr.83733.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000084114; ENSDARP00000078549; ENSDARG00000060016.
GeneID	556086.
KEGG	dre:556086.
Organism-specific databases
CTD	556086.
ZFIN	ZDB-GENE-080519-3. nsd1a.
Phylogenomic databases
GeneTree	ENSGT00700000104009.
KO	K15588.
Gene expression databases
ArrayExpress	F1QA79.
Bgee	F1QA79.
Family and domain databases
Gene3D	3.30.40.10. 3 hits.
InterPro	IPR006560. AWS. IPR003616. Post-SET_dom. IPR000313. PWWP. IPR001214. SET_dom. IPR019786. Zinc_finger_PHD-type_CS. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF00628. PHD. 2 hits. PF00855. PWWP. 2 hits. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00570. AWS. 1 hit. SM00249. PHD. 4 hits. SM00508. PostSET. 1 hit. SM00293. PWWP. 2 hits. SM00184. RING. 2 hits. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF57903. FYVE_PHD_ZnF. 3 hits.
PROSITE	PS51215. AWS. 1 hit. PS50868. POST_SET. 1 hit. PS50812. PWWP. 2 hits. PS50280. SET. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	20881309.

Entry information

Entry name

F1QA79_DANRE

Accession

Primary (citable) accession number: F1QA79

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	April 3, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)