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F1Q5B5

- F1Q5B5_DANRE

UniProt

F1Q5B5 - F1Q5B5_DANRE

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Protein

Alkaline phosphatase

Gene
alpl, alp
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

GO - Molecular functioni

  1. alkaline phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphataseUniRule annotation (EC:3.1.3.1UniRule annotation)
Gene namesi
Name:alplImported
Synonyms:alpImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 11

Organism-specific databases

ZFINiZDB-GENE-040420-1. alpl.

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiF1Q5B5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000008704.
KOiK01077.
OMAiRGNCAST.
OrthoDBiEOG7SN8CH.
TreeFamiTF323513.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1Q5B5-1 [UniParc]FASTAAdd to Basket

« Hide

MWECGCFLVL WSELSVVWHP WNVKIRKRRL IDNKMKVVQL LILSCLVWEG    50
KTKVQFPEQE KRPDYWRDFA QRSLKDALKL QELNKNIAKN IILFLGDGMG 100
VPTVTAARIL KGQLSGQNGE ETQLEMDKFP HVALSKTYNT NAQVPDSAGT 150
ATAFLCGVKA NEGTVGVSAA AVRSQCNTTQ GNEVTSILKW AKDAGKSVGI 200
VTTTRVNHAT PSAAYAHCVD RDWYSDADMP NEALQSGCKD IARQLFENIP 250
DINVIMGGGR RSMYPKNTPD VEYPGDKKQN GTRKDGRNLV GEWIDRVKEK 300
RGFYVWNKKD LLSLNPNNVD YLLGLFEPAD LNYELERNTE NDPSLTEMVD 350
VAIKILKKNE RGFFLLVEGG RIDHGHHEGK AKQALHEAVE MDRAITRAGL 400
LTSEYDTLTV VTADHSHVFS FGGYTPRGNS IFGLAPTLSD VDQKPFTAIL 450
YGNGPGFKLV NGARENVSTV DYQQNNYQAQ SAVPLRMETH GGEDVAIFSK 500
GPMAHLLHGV QEQHYIPHVM AYAACIGQNK DHCRTNSGSS SYFSHISPAL 550
LFPLLVKWLL C 561
Length:561
Mass (Da):62,469
Last modified:May 3, 2011 - v1
Checksum:i4F148EE558E64BFD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248318 Genomic DNA. No translation available.
RefSeqiXP_005169329.1. XM_005169272.1.
UniGeneiDr.116988.

Genome annotation databases

EnsembliENSDART00000146461; ENSDARP00000117214; ENSDARG00000015546.
GeneIDi393982.
KEGGidre:393982.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX248318 Genomic DNA. No translation available.
RefSeqi XP_005169329.1. XM_005169272.1.
UniGenei Dr.116988.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000146461 ; ENSDARP00000117214 ; ENSDARG00000015546 .
GeneIDi 393982.
KEGGi dre:393982.

Organism-specific databases

CTDi 249.
ZFINi ZDB-GENE-040420-1. alpl.

Phylogenomic databases

GeneTreei ENSGT00390000008704.
KOi K01077.
OMAi RGNCAST.
OrthoDBi EOG7SN8CH.
TreeFami TF323513.

Miscellaneous databases

PROi F1Q5B5.

Gene expression databases

Bgeei F1Q5B5.

Family and domain databases

Gene3Di 3.40.720.10. 1 hit.
InterProi IPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view ]
Pfami PF00245. Alk_phosphatase. 1 hit.
[Graphical view ]
PRINTSi PR00113. ALKPHPHTASE.
SMARTi SM00098. alkPPc. 1 hit.
[Graphical view ]
SUPFAMi SSF53649. SSF53649. 1 hit.
PROSITEi PS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiF1Q5B5_DANRE
AccessioniPrimary (citable) accession number: F1Q5B5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 14, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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