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Protein
Submitted name:

Transglutaminase 2

Gene

TGM2

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei277UniRule annotation1
Active sitei335UniRule annotation1
Active sitei358UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transglutaminase 2Imported
Gene namesi
Name:TGM2Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1Q435.

Expressioni

Gene expression databases

BgeeiENSCAFG00000008869.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000013036.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini269 – 361TGcInterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG410IFMV. Eukaryota.
ENOG410XQEZ. LUCA.
GeneTreeiENSGT00760000119108.
InParanoidiF1Q435.
KOiK05625.
OMAiAHITNNT.
OrthoDBiEOG091G030K.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiView protein in InterPro
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR036985. Transglutaminase-like_sf.
IPR023608. Transglutaminase_animal.
IPR013808. Transglutaminase_AS.
IPR008958. Transglutaminase_C.
IPR036238. Transglutaminase_C_sf.
IPR001102. Transglutaminase_N.
PfamiView protein in Pfam
PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiView protein in SMART
SM00460. TGc. 1 hit.
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiView protein in PROSITE
PS00547. TRANSGLUTAMINASES. 1 hit.

Sequencei

Sequence statusi: Complete.

F1Q435-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDLVLEKC DLELEANGRD HHTAGLCQGR LVVRRGQPFW LTLHFTGRSY
60 70 80 90 100
ESSVDSLTFS AVTGPDPSEE AGTKARFSLS SAVEEGAWTA VVMDQQDSVL
110 120 130 140 150
SLQLSTPPNA PVGLYRLSLE ASTGYQGSSF VLGHFTLLFN SWCPADAVYL
160 170 180 190 200
DSDEERREYV LSQQGFIYQG SVKFIKSIPW NFGQFEDGIL DICLMLLDRN
210 220 230 240 250
PKFLKDACRD CSSRSNPIYV GRVVSAMVNC NDDQGVLLGR WDNNYKDGIS
260 270 280 290 300
PMFWIGSVDI LRRWKTSGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN
310 320 330 340 350
FNSAHDQNSN LLIEYVYNKF GEIQKEKSEM IWNYHCWVES WMSRPDLQPG
360 370 380 390 400
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA AFVFAEVNAD
410 420 430 440 450
VVNWIQQDDG SLCKSTNNSQ TVGMKISTKS VGRDEREDIT HNYKYPEGSP
460 470 480 490 500
EEREAFRKAN HLNKLTEKEE TGLAMRIRVS ESMSMGSDFD VFAYINNNTS
510 520 530 540 550
ESHSCRLLLH ARTVSYNGIL GPECGTKDLL NLSLEPFSEK SIPLRILYEK
560 570 580 590 600
YCECLTESNL IKVRGLLVEQ AANNYLLAER DIYLENPEIK IRILGEPKQN
610 620 630 640 650
RKLVAEASLR NPLTVPLLGC SFTMEGAGLT EEQKVMDVPD PVEAGEEVKV
660 670 680
RVDLLPRHVG RHKLVVNFES DKLKAVKGFR NVLIGPA
Length:687
Mass (Da):77,151
Last modified:October 31, 2012 - v2
Checksum:i1ABD6A1EAAFF629C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03013924 Genomic DNA. No translation available.
RefSeqiXP_542991.4. XM_542991.5.

Genome annotation databases

EnsembliENSCAFT00000014092; ENSCAFP00000013036; ENSCAFG00000008869.
GeneIDi485867.
KEGGicfa:485867.

Similar proteinsi

Entry informationi

Entry nameiF1Q435_CANLF
AccessioniPrimary (citable) accession number: F1Q435
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: October 25, 2017
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported