Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Gastric intrinsic factor

Gene

GIF

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-196741. Cobalamin (Cbl, vitamin B12) transport and metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Gastric intrinsic factorImported
Gene namesi
Name:GIFImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 21

Organism-specific databases

VGNCiVGNC:41212. GIF.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500326756218 – 417Sequence analysisAdd BLAST400

Structurei

3D structure databases

ProteinModelPortaliF1PRL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini340 – 415DUF4430InterPro annotationAdd BLAST76

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IVBN. Eukaryota.
ENOG410XSU1. LUCA.
GeneTreeiENSGT00530000063370.
OMAiAENVNHK.
OrthoDBiEOG091G095C.
TreeFamiTF333092.

Family and domain databases

InterProiView protein in InterPro
IPR002157. Cbl-bd_prot.
IPR027954. DUF4430.
PfamiView protein in Pfam
PF01122. Cobalamin_bind. 1 hit.
PF14478. DUF4430. 1 hit.
PROSITEiView protein in PROSITE
PS00468. COBALAMIN_BINDING. 1 hit.

Sequencei

Sequence statusi: Complete.

F1PRL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWFSLHLLH LLWVAAGTST WARSSCSVPQ AAQHLVDGLQ VLLEDSVSSA
60 70 80 90 100
APPNPSVLIA MNLAGALSAE ARELLADRLG AGDSAGLSVG QLALTIMALN
110 120 130 140 150
SSCRDPGNKV SVLYGQMEAW PPSSPSAPAW TFYGPSLAVL ALCQEHPGRA
160 170 180 190 200
LPVAARLAKI LAAGLSPFNT DTGAMVTLAL TCMYNKIPEG SEEGYRTLFS
210 220 230 240 250
QVLKDVVENI SMRIKDNGII GDVYSTGLAM QALSVTPEPP NKEWDCKKTM
260 270 280 290 300
DTILKEIEQG KFHNPMSIAQ ILPSLKGKTY LDVPYVSCSP GHQVQPTLPS
310 320 330 340 350
QPSPVPTSAS NITVAYTINN QLKGVELVFN ETIDVSVKDG SVLLVVLEEA
360 370 380 390 400
QRRNPMFKFV TTMTSWGLVV SSINNIAESV HDRTYWQFLS GKTPLNEGVA
410
DYTPRDHEHI TANFTQY
Length:417
Mass (Da):44,980
Last modified:May 3, 2011 - v1
Checksum:i92305D2CD31B2AB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03013048 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCAFT00000016414; ENSCAFP00000015184; ENSCAFG00000010325.

Similar proteinsi

Entry informationi

Entry nameiF1PRL7_CANLF
AccessioniPrimary (citable) accession number: F1PRL7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: March 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported