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Protein
Submitted name:

Cytoplasmic FMR1 interacting protein 2

Gene

CYFIP2

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-2029482. Regulation of actin dynamics for phagocytic cup formation.
R-CFA-4420097. VEGFA-VEGFR2 Pathway.
R-CFA-5663213. RHO GTPases Activate WASPs and WAVEs.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytoplasmic FMR1 interacting protein 2Imported
Gene namesi
Name:CYFIP2Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1PMM7.

Expressioni

Gene expression databases

BgeeiENSCAFG00000017484.

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000025820.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3534. Eukaryota.
ENOG410XPKW. LUCA.
GeneTreeiENSGT00500000044831.
InParanoidiF1PMM7.
OMAiVWRGPPP.
OrthoDBiEOG091G0105.
TreeFamiTF312925.

Family and domain databases

InterProiView protein in InterPro
IPR008081. Cytoplasmic_FMR1-int.
IPR009828. DUF1394.
PANTHERiPTHR12195. PTHR12195. 1 hit.
PfamiView protein in Pfam
PF07159. DUF1394. 1 hit.
PF05994. FragX_IP. 1 hit.
PIRSFiPIRSF008153. FMR1_interacting. 1 hit.
PRINTSiPR01698. CYTOFMRPINTP.

Sequencei

Sequence statusi: Complete.

F1PMM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMLTLTCGR VSAAEEILTC EATSCHSKLG SLCNLQHAQC IHGKAGCTPV
60 70 80 90 100
QKTAAAAMTT HVTLEDALSN VDLLEELPLP DQQPCIEPPP SSIMYQANFD
110 120 130 140 150
TNFEDRNAFV TGIARYIEQA TVHSSMNEML EEGHEYAVML YTWRSCSRAI
160 170 180 190 200
PQVKCNEQPN RVEIYEKTVE VLEPEVTKLM KFMYFQRKAI ERFCSEVKRL
210 220 230 240 250
CHAERRKDFV SEAYLLTLGK FINMFAVLDE LKNMKCSVKN DHSAYKRAAQ
260 270 280 290 300
FLRKMADPQS IQESQNLSMF LANHNRITQC LHQQLEVIPG YEELLADIVN
310 320 330 340 350
ICVDYYENKM YLTPSEKHML LKVMGFGLYL MDGNVSNIYK LDAKKRINLS
360 370 380 390 400
KIDKFFKQLQ VVPLFGDMQI ELARYIKTSA HYEENKSKWT CTQSSISPQY
410 420 430 440 450
NICEQMVQIR DDHIRFISEL ARYSNSEVVT GSGLDSQKSD EEYRELFDLA
460 470 480 490 500
LRGLQLLSKW SAHVMEVYSW KLVHPTDKFC NKDCPGTAEE YERATRYNYT
510 520 530 540 550
SEEKFAFVEV IAMIKGLQVL MGRMESVFNQ AIRNTIYAAL QDFAQVTLRE
560 570 580 590 600
PLRQAVRKKK NVLISVLQAI RKTICDWEGG REPPNDPCLR GEKDPKGGFD
610 620 630 640 650
IKVPRRAVGP SSTQLYMVRT MLESLIADKS GSKKTLRSSL DGPIVLAIED
660 670 680 690 700
FHKQSFFFTH LLNISEALQQ CCDLSQLWFR EFFLELTMGR RIQFPIEMSM
710 720 730 740 750
PWILTDHILE TKEPSMMEYV LYPLDLYNDS AYYALTKFKK QFLYDEIEAE
760 770 780 790 800
VNLCFDQFVY KLADQIFAYY KAMAGSVLLD KRFRAECKNY GVIIPYPPSN
810 820 830 840 850
RYETLLKQRH VQLLGRSIDL NRLITQRISA AMYKSLDQAI SRFESEDLTS
860 870 880 890 900
IVELEWLLEI NRLTHRLLCK HMTLDSFDAM FREANHNVSA PYGRITLHVF
910 920 930 940 950
WELNFDFLPN YCYNGSTNRF VRTAIPFTQE PQRDKPANVQ PYYLYGSKPL
960 970 980 990 1000
NIAYSHIYSS YRNFVGPPHF KTICRLLGYQ GIAVVMEELL KIVKSLLQGT
1010 1020 1030 1040 1050
ILQYVKTLIE VMPKICRLPR HEYGSPGILE FFHHQLKDII EYAELKTDVF
1060 1070 1080 1090 1100
QSLREVGNAI LFCLLIEQAL SQEEVCDLLH AAPFQNILPR VYIKEGERLE
1110 1120 1130 1140 1150
VRMKRLEAKY APLHLVPLIE RLGTPQQIAI AREGDLLTKE RLCCGLSMFE
1160 1170 1180 1190 1200
VILTRIRSYL QDPIWRGPPP TNGVMHVDEC VEFHRLWSAM QFVYCIPVGT
1210 1220 1230 1240 1250
NEFTAEQCFG DGLNWAGCSI IVLLGQQRRF DLFDFCYHLL KVQRQDGKDE
1260 1270 1280 1290 1300
VIKNVPLKKM ADRIRKYQIL NNEVFAILNK YMKSVETDSS TVEHVRCFQP
1310
PIHQSLATTC
Length:1,310
Mass (Da):151,530
Last modified:October 31, 2012 - v2
Checksum:iE618636B8EAB38B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03003062 Genomic DNA. No translation available.
AAEX03003063 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCAFT00000027770; ENSCAFP00000025820; ENSCAFG00000017484.

Similar proteinsi

Entry informationi

Entry nameiF1PMM7_CANLF
AccessioniPrimary (citable) accession number: F1PMM7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: October 25, 2017
This is version 35 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported