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Protein
Submitted name:

Protection of telomeres 1

Gene

POT1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-2559586 DNA Damage/Telomere Stress Induced Senescence

Names & Taxonomyi

Protein namesi
Submitted name:
Protection of telomeres 1Imported
Gene namesi
Name:POT1Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 14

Organism-specific databases

VGNCiVGNC:44823 POT1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1P716

Expressioni

Gene expression databases

BgeeiENSCAFG00000001754

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000002549

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 288Telo_bindInterPro annotationAdd BLAST131

Phylogenomic databases

eggNOGiKOG4757 Eukaryota
ENOG410Z1J0 LUCA
GeneTreeiENSGT00390000018285
InParanoidiF1P716
KOiK11109
OMAiDKTSWIP
OrthoDBiEOG091G01T8
TreeFamiTF328398

Family and domain databases

InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR028389 POT1
IPR032042 POT1PC
IPR011564 Telomer_end-bd_POT1/Cdc13
PANTHERiPTHR14513 PTHR14513, 1 hit
PfamiView protein in Pfam
PF02765 POT1, 1 hit
PF16686 POT1PC, 1 hit
SMARTiView protein in SMART
SM00976 Telo_bind, 1 hit
SUPFAMiSSF50249 SSF50249, 2 hits

Sequencei

Sequence statusi: Complete.

F1P716-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLELIKEVN GVPEVELLGE LNKVEFRSLQ PGCDYSKKYI QGKLSLISSL
60 70 80 90 100
TYGGNRTAVL KIALQEQENS NSDTNTVNVL FFGKLAKDCA KVFYEGDTIA
110 120 130 140 150
VAGFAVLSAS SSTSRDGKHC LFLKAFEDFK STVYVYVKSV RDFSAESMSL
160 170 180 190 200
VPTTHYIYTP LNQLKGGTVV NVYGVVKFFK PPYLSKGTDY CSVVTIVDQT
210 220 230 240 250
NVKLTCMLFS GNYEALPIIY KNGDIVRFHR LKIQVYKNET QGITSSGFAS
260 270 280 290 300
LTFEGTLGAP VIPRTSSKYF NFTAEDQKMV EALRVWASTH ISPSSTLVKL
310 320 330 340 350
CDVQPLQYFD LTCQLLGKAE VDGASFLLKV WDGTRTPFPS WRVLIQDLVL
360 370 380 390 400
EGDLSHIHRL QNLTVDILVY DNHVQVAKSL KVGSFLRIYS LHTKLQSLNS
410 420 430 440 450
ENQATLLALE FHLHGGTSYG RGIRVLPESN SDVDQLKKVL ESADLTASQC
460 470 480 490 500
SDAICHSEQE DSLRTLSSSG SVSLYEIERC QQLSATILTD HQYLEKTPIC
510 520 530 540 550
TILKQKAPQQ YRIRAKLRSY KPRRLFQSVK LHCPKCHALQ EVPHEGDMDI
560 570 580 590 600
ILQEGASKTP DTKLQNTSLY DSKMWTTTDQ GERNVAVHFV KNNGILPLSS
610 620 630 640 650
DCLILIEGGT LSEICKLADK FHSVIPVRSG HEDLEVLDLS APFLIQGKIH
660 670 680 690 700
HYGCKQCSTL RPIQNLNSLV DKTQWIPSSV AEVLGIVPLQ HVFVMTFTLD
710 720 730 740 750
DGTGVLEAYL MDSDKFFQIP ASEILINDDL QQSMDSIMDM FCPSGIKIDA
760 770 780
YPWLECFIKS YNVTSGTEQQ ICYQIFDTTV AEDII
Length:785
Mass (Da):87,648
Last modified:October 31, 2012 - v2
Checksum:iBBDA4DAEDF9EA1AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03009277 Genomic DNA No translation available.
RefSeqiXP_005628494.1, XM_005628437.2
XP_005628495.1, XM_005628438.2
XP_005628496.1, XM_005628439.2
XP_005628497.1, XM_005628440.2

Genome annotation databases

EnsembliENSCAFT00000002746; ENSCAFP00000002549; ENSCAFG00000001754
GeneIDi609119
KEGGicfa:609119

Similar proteinsi

Entry informationi

Entry nameiF1P716_CANLF
AccessioniPrimary (citable) accession number: F1P716
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: March 28, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health