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Protein

Chloride intracellular channel protein

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChloride channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation
Biological processIon transport, Transport
LigandChloride

Names & Taxonomyi

Protein namesi
Recommended name:
Chloride intracellular channel proteinUniRule annotation
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiF1P2Y2

Expressioni

Gene expression databases

BgeeiENSGALG00000016020

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 229GST C-terminalInterPro annotationAdd BLAST172

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili114 – 134Sequence analysisAdd BLAST21

Domaini

Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.UniRule annotation

Sequence similaritiesi

Belongs to the chloride channel CLIC family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410INGY Eukaryota
ENOG4110FKA LUCA
GeneTreeiENSGT00550000074477
InParanoidiF1P2Y2
OrthoDBiEOG091G0IHT
TreeFamiTF315438

Family and domain databases

InterProiView protein in InterPro
IPR002946 CLIC
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
PRINTSiPR01263 INTCLCHANNEL
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR00862 O-ClC, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit

Sequencei

Sequence statusi: Complete.

F1P2Y2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SAGSDGESIG NCPFSQRLFM ILWLKGVIFN VTTVDLKRKP ADLQNLAPGT
60 70 80 90 100
NPPFMTFDGE VKTDVNKIEE FLEEKLAPPR YPKLAPKHPE SNSAGNDVFA
110 120 130 140 150
KFSAFIKNPR KDANENLEKS LLKALRKLDN YLNSPLPDEI DAYSTEEITV
160 170 180 190 200
SCRKFLDGDE LTLADCNLLP KLHIIKVVAK KYRNFDFPPE MTGISRYLNN
210 220
AYARDEFTNT CPADQEIEYA YLDVAKRMK
Length:229
Mass (Da):25,917
Last modified:February 15, 2017 - v4
Checksum:i25CFB4002D51DC98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000269 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSGALT00000025807; ENSGALP00000025760; ENSGALG00000016020

Similar proteinsi

Entry informationi

Entry nameiF1P2Y2_CHICK
AccessioniPrimary (citable) accession number: F1P2Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: February 15, 2017
Last modified: March 28, 2018
This is version 49 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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