F1P2A6 (F1P2A6_CHICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Adenosine deaminase Ensembl ENSGALP00000006620

Gene names

Name:

ADA Ensembl ENSGALP00000006620

Organism

Gallus gallus (Chicken) [Reference proteome] Ensembl ENSGALP00000006620

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSGALP00000006620

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	Peyer's patch development Inferred from electronic annotation. Source: Compara T cell activation Inferred from electronic annotation. Source: Compara adenosine catabolic process Inferred from electronic annotation. Source: Compara dATP catabolic process Inferred from electronic annotation. Source: Compara deoxyadenosine catabolic process Inferred from electronic annotation. Source: Compara embryonic digestive tract development Inferred from electronic annotation. Source: Compara germinal center B cell differentiation Inferred from electronic annotation. Source: Compara hypoxanthine biosynthetic process Inferred from electronic annotation. Source: Compara inosine biosynthetic process Inferred from electronic annotation. Source: Compara liver development Inferred from electronic annotation. Source: Compara lung alveolus development Inferred from electronic annotation. Source: Compara negative regulation of adenosine receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of inflammatory response Inferred from electronic annotation. Source: Compara negative regulation of leukocyte migration Inferred from electronic annotation. Source: Compara negative regulation of mature B cell apoptotic process Inferred from electronic annotation. Source: Compara negative regulation of mucus secretion Inferred from electronic annotation. Source: Compara negative regulation of penile erection Inferred from electronic annotation. Source: Compara negative regulation of thymocyte apoptotic process Inferred from electronic annotation. Source: Compara placenta development Inferred from electronic annotation. Source: Compara positive regulation of B cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of T cell differentiation in thymus Inferred from electronic annotation. Source: Compara positive regulation of T cell receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of alpha-beta T cell differentiation Inferred from electronic annotation. Source: Compara positive regulation of calcium-mediated signaling Inferred from electronic annotation. Source: Compara positive regulation of germinal center formation Inferred from electronic annotation. Source: Compara positive regulation of heart rate Inferred from electronic annotation. Source: Compara positive regulation of smooth muscle contraction Inferred from electronic annotation. Source: Compara purine nucleotide salvage Inferred from electronic annotation. Source: Compara purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: InterPro regulation of cell-cell adhesion mediated by integrin Inferred from electronic annotation. Source: Compara response to hypoxia Inferred from electronic annotation. Source: Compara trophectodermal cell differentiation Inferred from electronic annotation. Source: Compara xanthine biosynthetic process Inferred from electronic annotation. Source: Compara
Cellular_component	external side of plasma membrane Inferred from electronic annotation. Source: Compara lysosome Inferred from electronic annotation. Source: Compara
Molecular_function	adenosine deaminase activity Inferred from electronic annotation. Source: Compara zinc ion binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1P2A6 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: BD24D36A6AC9FAFA	FASTA	357	40,698
	10 20 30 40 50 60 MERGVRVFGE PKVELHIHLD GAIRPETILH FGKKRGVPLP GSTVDELMKH VSYQTPLSLK 70 80 90 100 110 120 LFLEKFNHYM PAIAGDREAV RRIAYELVET KAKEGVVYVE VRYSPHLLAN CRVEPIPWGQ 130 140 150 160 170 180 AEGDLTPEEV VNLVNQGLQD GERDFRIKAR SILCCMRHMP SWSPEVVELC KKYQNNSVVA 190 200 210 220 230 240 IDLAGDELLM ASSDHKAAYE EAERCGIHRT VHAGEAGPAT MIKEAVYLLK AERIGHGYHV 250 260 270 280 290 300 LEDPELYREL MRTRMHFEVC PWSSYLTGAC LPDFRKHPVV QFKKDQANYS INTDDPLIFN 310 320 330 340 350 SNIDKDYGIV KEYMDFTEED FKRVNINAAQ SSFLPEKEKQ ELLNTLYEAY GMVPATS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution." International Chicken Genome Sequencing Consortium Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A. , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K. Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Red jungle fowl Ensembl ENSGALP00000006620.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Red jungle fowl Ensembl ENSGALP00000006620.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AADN02019323 Genomic DNA. No translation available.
IPI	IPI00588756.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSGALT00000006631; ENSGALP00000006620; ENSGALG00000004170.
Phylogenomic databases
GeneTree	ENSGT00640000091458.
OMA	MPAIAGC.
Family and domain databases
HAMAP	MF_00540. A_deaminase.
InterPro	IPR006650. A/AMP_deam_AS. IPR001365. A/AMP_deaminase_dom. IPR006330. Ado/ade_deaminase. [Graphical view]
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. aden_deam. 1 hit.
PROSITE	PS00485. A_DEAMINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F1P2A6_CHICK

Accession

Primary (citable) accession number: F1P2A6

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)