F1NVB5 (F1NVB5_CHICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nuclear receptor subfamily 5 group A member 2 Ensembl ENSGALP00000003413

Gene names

Name:

NR5A2 Ensembl ENSGALP00000003413

Organism

Gallus gallus (Chicken) [Reference proteome] Ensembl ENSGALP00000003413

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the nuclear hormone receptor family. RuleBase RU000377 Contains 1 nuclear receptor DNA-binding domain. SAAS SAAS000536
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSGALP00000003413

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU004334 SAAS SAAS000536
Cellular component	Nucleus RuleBase RU004334 SAAS SAAS000536
Domain	Zinc-finger RuleBase RU004334 SAAS SAAS000536
Ligand	DNA-binding RuleBase RU004334 SAAS SAAS000536 Metal-binding Zinc
Molecular function	Receptor RuleBase RU004334
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	bile acid metabolic process Inferred from electronic annotation. Source: Compara cholesterol homeostasis Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara positive regulation of viral genome replication Inferred from electronic annotation. Source: Compara regulation of cell proliferation Inferred from electronic annotation. Source: Compara transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	phospholipid binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara steroid hormone receptor activity Inferred from electronic annotation. Source: InterPro transcription regulatory region DNA binding Inferred from electronic annotation. Source: Compara zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1NVB5 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 69D4F54CD6786B11	FASTA	501	57,106
	10 20 30 40 50 60 MLPKVETEAL GLARSNGEQG QMPENMQVSQ FKMVNYSYDE DLEELCPVCG DKVSGYHYGL 70 80 90 100 110 120 LTCESCKGFF KRTVQNNKRY TCIENQNCQI DKTQRKRCPY CRFQKCLSVG MKLEAVRADR 130 140 150 160 170 180 MRGGRNKFGP MYKRDRALKQ QKKALIRANG LKLEAMTQVI QAMPTDLTIS SAIQNIHSAS 190 200 210 220 230 240 KGLPLNHTAL PPTDYDRSPF VTSPISMTMP PHGSLQGYQT YGHFPSRAIK SEYPDPYTSS 250 260 270 280 290 300 PESIMGYSYM DGYQTSSPAS IPHLILELLK CEPDEPQVQA KIMAYLQQEQ ANRSKHEKLN 310 320 330 340 350 360 TFGLMCKMAD QTLFSIVEWA RSSIFFRELK VDDQMKLLQN CWSELLILDH IYRQVVHGKE 370 380 390 400 410 420 GSILLVTGQQ VDYSVIASQA GATLNNLMSH AQELVAKLRS LQFDLREFVC LKFLVLFSLD 430 440 450 460 470 480 VKNLENFQLV EGVQEQVNAA LLDYTMCNYP QQTDKFGQLL LRLPEIRAIS MQAEEYLYYK 490 500 HLNGDVPCNN LLIEMLHAKR A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution." International Chicken Genome Sequencing Consortium Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A. , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K. Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Red jungle fowl Ensembl ENSGALP00000003413.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Red jungle fowl Ensembl ENSGALP00000003413.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AADN02033799 Genomic DNA. No translation available. AADN02033800 Genomic DNA. No translation available. AADN02033801 Genomic DNA. No translation available. AADN02033802 Genomic DNA. No translation available. AADN02033803 Genomic DNA. No translation available.
IPI	IPI00679374.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSGALT00000003418; ENSGALP00000003413; ENSGALG00000002182.
Phylogenomic databases
GeneTree	ENSGT00670000097927.
OMA	NTFGLMC.
Gene expression databases
ArrayExpress	F1NVB5.
Family and domain databases
Gene3D	1.10.565.10. 1 hit. 3.30.50.10. 1 hit.
InterPro	IPR008946. Nucl_hormone_rcpt_ligand-bd. IPR000536. Nucl_hrmn_rcpt_lig-bd_core. IPR016355. Steroidogenic_factor_1. IPR001723. Str_hrmn_rcpt. IPR001628. Znf_hrmn_rcpt. IPR013088. Znf_NHR/GATA. [Graphical view]
Pfam	PF00104. Hormone_recep. 1 hit. PF00105. zf-C4. 1 hit. [Graphical view]
PIRSF	PIRSF002530. Nuc_orph_FTZ-F1. 1 hit.
PRINTS	PR00398. STRDHORMONER. PR00047. STROIDFINGER.
SMART	SM00430. HOLI. 1 hit. SM00399. ZnF_C4. 1 hit. [Graphical view]
SUPFAM	SSF48508. Str_ncl_receptor. 1 hit.
PROSITE	PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F1NVB5_CHICK

Accession

Primary (citable) accession number: F1NVB5

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	April 3, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)