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Protein
Submitted name:

Secreted frizzled-related protein 1

Gene

SFRP1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinSAAS annotation

Keywords - Biological processi

Wnt signaling pathwaySAAS annotation

Protein family/group databases

MEROPSiI93.002.

Names & Taxonomyi

Protein namesi
Submitted name:
Secreted frizzled-related protein 1Imported
Gene namesi
Name:SFRP1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 22

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence analysisAdd
BLAST
Chaini32 – 312281Sequence analysisPRO_5003270930Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiF1NPV5.

Expressioni

Gene expression databases

BgeeiENSGALG00000003473.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005489.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 167117FZ (frizzled)InterPro annotationAdd
BLAST
Domaini184 – 304121NTRInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains FZ (frizzled) domain.SAAS annotation
Contains NTR domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3577. Eukaryota.
ENOG410XRC8. LUCA.
GeneTreeiENSGT00760000118864.
OMAiDDVCIAM.
OrthoDBiEOG091G0F7I.
TreeFamiTF350133.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR001134. Netrin_domain.
IPR018933. Netrin_module_non-TIMP.
IPR026559. SFRP1.
IPR008993. TIMP-like_OB-fold.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF87. PTHR11309:SF87. 1 hit.
PfamiPF01392. Fz. 1 hit.
PF01759. NTR. 1 hit.
[Graphical view]
SMARTiSM00643. C345C. 1 hit.
SM00063. FRI. 1 hit.
[Graphical view]
SUPFAMiSSF50242. SSF50242. 1 hit.
SSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50189. NTR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1NPV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AVGVAMGRVR GALRALLSLA AGLLACGGAS EYDYVSYQSD LGPYPGGRFY
60 70 80 90 100
TKPHQCVAIP ADLRLCHSVG YDKMVLPNLL DHETMAEVKH QASSWVPLLN
110 120 130 140 150
KNCHMGTQVF LCSLFAPVCL DRPVYPCRWL CEAVRDSCEP VMQFFGFFWP
160 170 180 190 200
EMLKCDQFPQ DDVCIAMTTP NATEVSRPKG TTVCPPCDNE MKSEAIVEHL
210 220 230 240 250
CASEFALKMT IKEVKKENGD KVIIPRKRKA LKLGPIRKKN LKKLVLLLKN
260 270 280 290 300
GADCPCHQLD NLGHHFLIMG RQVKTQHLLT AIYKWDKKNK EFKKFMKKVK
310
APDCPTFPSV FK
Length:312
Mass (Da):35,047
Last modified:May 3, 2011 - v1
Checksum:i037CD606ED3B17A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN03008089 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSGALT00000005499; ENSGALP00000005489; ENSGALG00000003473.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN03008089 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005489.

Protein family/group databases

MEROPSiI93.002.

Proteomic databases

PaxDbiF1NPV5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000005499; ENSGALP00000005489; ENSGALG00000003473.

Phylogenomic databases

eggNOGiKOG3577. Eukaryota.
ENOG410XRC8. LUCA.
GeneTreeiENSGT00760000118864.
OMAiDDVCIAM.
OrthoDBiEOG091G0F7I.
TreeFamiTF350133.

Gene expression databases

BgeeiENSGALG00000003473.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR001134. Netrin_domain.
IPR018933. Netrin_module_non-TIMP.
IPR026559. SFRP1.
IPR008993. TIMP-like_OB-fold.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF87. PTHR11309:SF87. 1 hit.
PfamiPF01392. Fz. 1 hit.
PF01759. NTR. 1 hit.
[Graphical view]
SMARTiSM00643. C345C. 1 hit.
SM00063. FRI. 1 hit.
[Graphical view]
SUPFAMiSSF50242. SSF50242. 1 hit.
SSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50189. NTR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF1NPV5_CHICK
AccessioniPrimary (citable) accession number: F1NPV5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 7, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.