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Protein
Submitted name:

Rho guanine nucleotide exchange factor 39

Gene

ARHGEF39

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-GGA-193648 NRAGE signals death through JNK
R-GGA-194840 Rho GTPase cycle
R-GGA-416482 G alpha (12/13) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 39Imported
Gene namesi
Name:ARHGEF39Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome Z

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1NHV7

Expressioni

Gene expression databases

BgeeiENSGALG00000002599

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 200DHInterPro annotationAdd BLAST176
Domaini230 – 334PHInterPro annotationAdd BLAST105

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili12 – 32Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IE9S Eukaryota
ENOG4110AJV LUCA
GeneTreeiENSGT00440000033863
InParanoidiF1NHV7
OMAiCPHLELY
OrthoDBiEOG091G0DTO
TreeFamiTF350447

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

F1NHV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYSPPAPMA GANTVEEQRA RWERKRSRTA KELLETEHRY LEQLDLVVTF
60 70 80 90 100
FVTILKAKGT LKPAVMETIF GPLESIYSAS QVLSLHLERG NLGLGLENFC
110 120 130 140 150
QKLELYGHYA ENFEQANKTL MEQLRKNKSF RRFKKLQETR PQFQGRKLED
160 170 180 190 200
LLPLPLQRLH QYKHFLRDLL ENTSPASAEY QKLAKAVKSV SEVSQWVQDI
210 220 230 240 250
ACKRENSLQL HRVQKLLKGQ KTRVLTPGRW YIREGWLLVV PSKGDELKRR
260 270 280 290 300
MFFLFSDILI STKPCHPLHL LNSTKFACTA VYPLHQCVVD KVFGHTQSEG
310 320 330
GLLSLSFPHK TLLLMSTDQQ DINDWYQSLT TAVRQLKA
Length:338
Mass (Da):39,082
Last modified:June 26, 2013 - v2
Checksum:iCD0021948C972EE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC189009 Genomic DNA No translation available.
RefSeqiNP_001182618.1, NM_001195689.1
XP_015132842.1, XM_015277356.1
XP_015132843.1, XM_015277357.1
XP_015132844.1, XM_015277358.1
UniGeneiGga.33815
Gga.49441

Genome annotation databases

EnsembliENSGALT00000004088; ENSGALP00000004079; ENSGALG00000002599
GeneIDi431661
KEGGigga:431661

Similar proteinsi

Entry informationi

Entry nameiF1NHV7_CHICK
AccessioniPrimary (citable) accession number: F1NHV7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: June 26, 2013
Last modified: March 28, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health