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Protein
Submitted name:

G protein-activated inward rectifier potassium channel 1

Gene

KCNJ3

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Voltage-gated channelUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotationSAAS annotation, Transport
LigandPotassium

Enzyme and pathway databases

ReactomeiR-GGA-1296041 Activation of G protein gated Potassium channels
R-GGA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-activated inward rectifier potassium channel 1Imported
Gene namesi
Name:KCNJ3Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei76 – 97HelicalSequence analysisAdd BLAST22
Transmembranei151 – 174HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSGALG00000012537

Family & Domainsi

Sequence similaritiesi

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827 Eukaryota
ENOG410XQ62 LUCA
GeneTreeiENSGT00760000118842
OrthoDBiEOG091G08HC
PhylomeDBiF1NCD3
TreeFamiTF313676

Family and domain databases

Gene3Di2.60.40.1400, 2 hits
InterProiView protein in InterPro
IPR014756 Ig_E-set
IPR016449 K_chnl_inward-rec_Kir
IPR003274 K_chnl_inward-rec_Kir3.1
IPR013518 K_chnl_inward-rec_Kir_cyto
PANTHERiPTHR11767 PTHR11767, 1 hit
PfamiView protein in Pfam
PF01007 IRK, 1 hit
PRINTSiPR01327 KIR31CHANNEL
PR01320 KIRCHANNEL
SUPFAMiSSF81296 SSF81296, 1 hit

Sequencei

Sequence statusi: Complete.

F1NCD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALRRKLGD EYQVVSTSAS GGGLPPPRAA PRGKRQRFVD KNGRCNVQHG
60 70 80 90 100
NLGGETSRYL SDLFTTLVDL KWRWNLFIFV LTYTVAWLFM ASMWWVIAYM
110 120 130 140 150
RGDLNKAHDD SYTPCVANVY NFPSAFLFFI ETEATIGYGH RYITDKCPEG
160 170 180 190 200
IVLFLFQSIL GSIVDAFLIG CMFIKMSQPK KRAETLMFSE HAAISMRDGK
210 220 230 240 250
LTLMFRVGNL RNSHMVSAQI RCKLLKSRQT PEGEFLPLDQ LELDVGFSTG
260 270 280 290 300
ADQLFLVSPL TICHVIDAKS PFYDLSQRSM QTEQFEIVVI LEGIVETTGM
310 320 330 340 350
TCQARTSYTE DEVLWGHRFF PVISLEEGFF KVDYSQFHAT FEVPTPPYSV
360 370 380 390 400
KEQEEMLLMS SPLIAPAVSN SKERNNSVEC LDGLDEVGIK LPSKLQKITG
410 420 430 440 450
RDDFPKKLLR MSSTTSEKAY SMGDLPMKLQ RISSVPGNSE EKLVSKATKM
460 470 480 490
MSDPMSQSVA DLPPKLQKLS GGGRMEGNLP PKLRKMNSDR FT
Length:492
Mass (Da):55,381
Last modified:November 30, 2016 - v2
Checksum:i8B0E844BA10A5864
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000046 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSGALT00000020476; ENSGALP00000020449; ENSGALG00000012537

Similar proteinsi

Entry informationi

Entry nameiF1NCD3_CHICK
AccessioniPrimary (citable) accession number: F1NCD3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: November 30, 2016
Last modified: March 28, 2018
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health