Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F1NB95

- F1NB95_CHICK

UniProt

F1NB95 - F1NB95_CHICK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Uncharacterized protein

Gene

PCSK1

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase activity Source: Ensembl

GO - Biological processi

  1. peptide biosynthetic process Source: Ensembl
  2. peptide hormone processing Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiREACT_242665. Synthesis, secretion, and deacylation of Ghrelin.
REACT_245409. Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1).
REACT_251189. Peptide hormone biosynthesis.
REACT_254277. Insulin processing.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PCSK1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome Z

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation
Contains peptidase S8 domain.SAAS annotation
Contains peptidase Sdomain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00750000117358.
InParanoidiF1NB95.
KOiK01359.
OrthoDBiEOG7BW0JD.
TreeFamiTF314277.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR022005. Proho_convert.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF12177. Proho_convert. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1NB95-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDGPRRAGRC AALALLAACC LARGGGAERQ FLNEWAAEVP AGPDAARAIA
60 70 80 90 100
EELDYDLVGQ IGSLKNHYLF RHKSHPRRSR RSAIHITKRL SDDERVSWAE
110 120 130 140 150
QQYEKKRTKR AAVTDSAENL FNDPMWNQQW YLQDTRITPS LPKLDLHVIP
160 170 180 190 200
VWQKGITGRG VVITVLDDGL EWNHTDIYAN YDPRASYDFN DNDYDPFPRY
210 220 230 240 250
DPTNENKHGT RCAGEIAMQA NNRKCGVGVA YNSKVGGIRM LDGIVTDAIE
260 270 280 290 300
ASSIGFNPEH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GIKQGRNGKG
310 320 330 340 350
SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST
360 370 380 390 400
LATAYSSGDY TDQRITSADL HNECTGTHTG TSASAPLAAG IFALALEANP
410 420 430 440 450
NLTWRDMQHL VVWTSEYDPL AGNPGWKKNG AGLMVNSRFG FGLLNANALV
460 470 480 490 500
DLADPKRWKG VPEKRECIVQ DKSFEPRLLR ANEEVIIEIP TKACEGQENS
510 520 530 540 550
IASLEHVQLE ATIEYSRRGD LHVTLVSPSG TSTVLLAERE RDKSPNGFKN
560 570 580 590 600
WDFMSVHTWG ENPTGTWVLR ITDVSKRIQN EGRIVNWKLI LHGTDTQPEH
610 620 630 640 650
MKQPRVYTSY NAVQNDRRGV EKMTDLAEDH TTQENLSEKN KVTQDIGSSR
660 670 680 690 700
NKAEDKFPSE AMLHLLRSAF SRQMAQKRLP KKTASEKLSI PYEHFYQALE
710 720 730 740
KLNKPSQLKD SEESLYSDYV DLFYNAKPYK HRDDRLLQAL VDIINEGN
Length:748
Mass (Da):83,683
Last modified:June 26, 2013 - v2
Checksum:iB1331F0E037CCF83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC188442 Genomic DNA. No translation available.
RefSeqiXP_003643108.1. XM_003643060.2.
UniGeneiGga.55664.

Genome annotation databases

EnsembliENSGALT00000023658; ENSGALP00000023612; ENSGALG00000014681.
GeneIDi769230.
KEGGigga:769230.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC188442 Genomic DNA. No translation available.
RefSeqi XP_003643108.1. XM_003643060.2.
UniGenei Gga.55664.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000023658 ; ENSGALP00000023612 ; ENSGALG00000014681 .
GeneIDi 769230.
KEGGi gga:769230.

Organism-specific databases

CTDi 5122.

Phylogenomic databases

GeneTreei ENSGT00750000117358.
InParanoidi F1NB95.
KOi K01359.
OrthoDBi EOG7BW0JD.
TreeFami TF314277.

Enzyme and pathway databases

Reactomei REACT_242665. Synthesis, secretion, and deacylation of Ghrelin.
REACT_245409. Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1).
REACT_251189. Peptide hormone biosynthesis.
REACT_254277. Insulin processing.

Miscellaneous databases

PROi F1NB95.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProi IPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR022005. Proho_convert.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view ]
PANTHERi PTHR10795. PTHR10795. 1 hit.
Pfami PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF12177. Proho_convert. 1 hit.
[Graphical view ]
PRINTSi PR00723. SUBTILISIN.
SUPFAMi SSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
    International Chicken Genome Sequencing Consortium
    Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
    , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
    Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Red jungle fowlImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Red jungle fowlImported.

Entry informationi

Entry nameiF1NB95_CHICK
AccessioniPrimary (citable) accession number: F1NB95
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: June 26, 2013
Last modified: November 26, 2014
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3