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F1N616

- F1N616_BOVIN

UniProt

F1N616 - F1N616_BOVIN

Protein
Submitted name:

Uncharacterized protein

Gene

HDAC7

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 2 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chromatin binding Source: Ensembl
    2. histone deacetylase activity Source: InterPro
    3. transcription corepressor activity Source: Ensembl

    GO - Biological processi

    1. cell-cell junction assembly Source: Ensembl
    2. negative regulation of interleukin-2 production Source: Ensembl
    3. negative regulation of osteoblast differentiation Source: Ensembl
    4. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    5. positive regulation of cell migration involved in sprouting angiogenesis Source: Ensembl
    6. vasculogenesis Source: Ensembl

    Keywords - Molecular functioni

    HydrolaseSAAS annotation

    Enzyme and pathway databases

    ReactomeiREACT_211655. NOTCH1 Intracellular Domain Regulates Transcription.
    REACT_221028. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
    REACT_225370. Constitutive Signaling by NOTCH1 PEST Domain Mutants.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:HDAC7Imported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 5

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. histone deacetylase complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliF1N616.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000062809.
    KOiK11408.
    OMAiAFRIVVM.
    OrthoDBiEOG7RFTH5.
    TreeFamiTF106174.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR023801. His_deacetylse_dom.
    IPR017320. Histone_deAcase_II_euk.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037911. HDAC_II_euk. 1 hit.
    PRINTSiPR01270. HDASUPER.

    Sequencei

    Sequence statusi: Complete.

    F1N616-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGNHLDPDG TQVSPAAPCS SPPIIGWPRP RADTPGPQPQ PMDLRVGQRP    50
    PVEPPPEPTL LALQHPQRLH HHLFLAGLQP QRSAEPMRLS MDTPMPELQM 100
    GQQEQELRQL LNKDKSKRSA VASSVVKQKL AEVILKKQQA ALERTVHPNS 150
    PSVPYRTLEP LETEGAARSM LSSFLPPVPS LPCDPPEHFP LRKTVSEPNL 200
    KLRYKPKKSL ERRKNPLLRK ESAPPSLRRR PAETLGDSSP SSSSTPASGC 250
    SSPNDSEHGP NPVLGSEALL GQRLRLQETS LAPFALLPTI TLGLPAPARA 300
    DGDRRTHATL GPRGPVLGNP HAHLFLPHGL EPEAGGPLPS RLQPILLLDP 350
    SVTHTPLLTV PGLGPLPFHF AQSLLTTERP SGSGLHRPLS RTRSEPLPPS 400
    ATTPSLLGPL QPRLERLKPH VQLIKRSAKP SEKPRLRQIP SAEDLETDGG 450
    SVGPLRDDGL EHRESSHGQQ EARGTVPLQQ HQQVFLWEQQ RLAGRLPRGA 500
    TGDSVLLPLA PGSHRPLSRA QSSPAAPASL STPEPASQAR ILPSSETPAR 550
    TLPFTTGLVY DSVMLKHQCS CGDNSRHPEH AGRIQSIWSR LLERGLRSQC 600
    ESLRGRKASL EELQSVHSER HVLLYGTNPL SRLKLDNGKL AGLLAQRMFV 650
    MLPCGGVGVD TDTIWNELHS SNAARWAAGS VTDLAFKVAS RELKNGFAVV 700
    RPPGHHADHS TAMGFCFFNS VAIACRQLQQ QGKASKILIV DWDVHHGNGT 750
    QQTFYQDPNV LYISLHRHDD GNFFPGSGAV DEVGAGSGEG FNVNVAWAGG 800
    LDPPMGDPEY LAAFRIVVMP IAREFSPDLV LVSAGFDAAE GHPPPLGGYH 850
    VSAKCFGYMT QQLMSLAGGA VVLALEGGHD LTAICDASEA CVAALLGNKV 900
    DPLSEEGWKQ KPNLNAIRSL EAVIRVHSEY WGCMQRLASR PDSWVHRVPG 950
    ADAEEVEAVT ALASLSVGIL AEERTSGQLV EEEEPMNL 988
    Length:988
    Mass (Da):106,852
    Last modified:November 16, 2011 - v2
    Checksum:iD0718D2FE4795A26
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02012987 Genomic DNA. No translation available.
    RefSeqiNP_001180070.1. NM_001193141.1.
    UniGeneiBt.2919.

    Genome annotation databases

    EnsembliENSBTAT00000038321; ENSBTAP00000038136; ENSBTAG00000026819.
    GeneIDi509843.
    KEGGibta:509843.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02012987 Genomic DNA. No translation available.
    RefSeqi NP_001180070.1. NM_001193141.1.
    UniGenei Bt.2919.

    3D structure databases

    ProteinModelPortali F1N616.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000038321 ; ENSBTAP00000038136 ; ENSBTAG00000026819 .
    GeneIDi 509843.
    KEGGi bta:509843.

    Organism-specific databases

    CTDi 51564.

    Phylogenomic databases

    GeneTreei ENSGT00530000062809.
    KOi K11408.
    OMAi AFRIVVM.
    OrthoDBi EOG7RFTH5.
    TreeFami TF106174.

    Enzyme and pathway databases

    Reactomei REACT_211655. NOTCH1 Intracellular Domain Regulates Transcription.
    REACT_221028. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
    REACT_225370. Constitutive Signaling by NOTCH1 PEST Domain Mutants.

    Miscellaneous databases

    NextBioi 20869160.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR023801. His_deacetylse_dom.
    IPR017320. Histone_deAcase_II_euk.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037911. HDAC_II_euk. 1 hit.
    PRINTSi PR01270. HDASUPER.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiF1N616_BOVIN
    AccessioniPrimary (citable) accession number: F1N616
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3