F1N3X6 (F1N3X6_BOVIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Uncharacterized protein Ensembl ENSBTAP00000007206
Organism	Bos taurus (Bovine) [Reference proteome] Ensembl ENSBTAP00000007206
Taxonomic identifier	9913 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the AB hydrolase superfamily. Lipase family. RuleBase RU004262
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSBTAP00000007206

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS013818
Molecular function	Hydrolase RuleBase RU004263
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cholesterol homeostasis Inferred from electronic annotation. Source: Compara cholesterol metabolic process Inferred from electronic annotation. Source: Compara cholesterol transport Inferred from electronic annotation. Source: Compara fatty acid biosynthetic process Inferred from electronic annotation. Source: Compara high-density lipoprotein particle remodeling Inferred from electronic annotation. Source: Compara low-density lipoprotein particle remodeling Inferred from electronic annotation. Source: Compara triglyceride catabolic process Inferred from electronic annotation. Source: Compara triglyceride homeostasis Inferred from electronic annotation. Source: Compara very-low-density lipoprotein particle remodeling Inferred from electronic annotation. Source: Compara
Cellular_component	extracellular space Inferred from electronic annotation. Source: Compara
Molecular_function	triglyceride lipase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	168	1	Nucleophile By similarity PIRSR PIRSR000865-1
	Active site	194	1	Charge relay system By similarity PIRSR PIRSR000865-1
	Active site	280	1	Charge relay system By similarity PIRSR PIRSR000865-1

Sequences

	Sequence		Length	Mass (Da)
	F1N3X6 [UniParc]. Last modified November 16, 2011. Version 2. Checksum: C2EBF7DF8CD4D6BC	FASTA	501	56,846
	10 20 30 40 50 60 MENPLCVSIF LFYCILIQSS AHGQSLGPES FGRRSRAAET NKTPQETRTK FLLFRGETDK 70 80 90 100 110 120 GCQILLNHSD TLQQCGFNSS LPLVMIVHGW LVDDILEDWV WEMVAALKSQ LAQSVNVGLA 130 140 150 160 170 180 EWVTLAHNHY TTAVRNTRLV GQEIAALLQW LQESVQFSPS HVHLIGYSLG AHVSGFAGSY 190 200 210 220 230 240 MSRKHKIGRI TVIDCCSPRS SRAQFSDGLI PQQAGFLSTL MSFHWNVPGL SVKGLTGLLW 250 260 270 280 290 300 PPKFHPNDGT KLPGVHFHTL LRKEAFQGLP SITRTVKCAH ERSVHLFIDS LLHADMQSMA 310 320 330 340 350 360 YLCRDMDRFS QGLCLSCKKG RCNTLGYHTR QERQSKKSKS LFLVTRAQSP FKVYHYQFKI 370 380 390 400 410 420 RFINQTENPV EPTFTVSFLG TRGERQKIPI TLSKGITSNE TYSFLITLDV DIGELIMIKF 430 440 450 460 470 480 KWENRMVWSN VWNTVQTIIP WGRGSLHSGL ALKSIRVKVG ETQQRMTFCS ENMNDLLLHP 490 500 AREKTFVRCE ANSETLKRKI R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol. 10:R42-R42(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hereford Ensembl ENSBTAP00000007206.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Hereford Ensembl ENSBTAP00000007206.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DAAA02028828 Genomic DNA. No translation available. DAAA02028829 Genomic DNA. No translation available. DAAA02028830 Genomic DNA. No translation available. DAAA02028831 Genomic DNA. No translation available. DAAA02028832 Genomic DNA. No translation available.
IPI	IPI00714758.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000007206; ENSBTAP00000007206; ENSBTAG00000005479.
Phylogenomic databases
GeneTree	ENSGT00560000077136.
OMA	CHFLELY.
Family and domain databases
Gene3D	2.60.60.20. 1 hit.
InterPro	IPR000734. Lipase. IPR002333. Lipase_hep. IPR008976. Lipase_LipOase. IPR013818. Lipase_N. IPR001024. LipOase_LH2. IPR016272. Lipoprotein_lipase_LIPH. [Graphical view]
PANTHER	PTHR11610. PTHR11610. 1 hit. PTHR11610:SF2. PTHR11610:SF2. 1 hit.
Pfam	PF00151. Lipase. 1 hit. PF01477. PLAT. 1 hit. [Graphical view]
PIRSF	PIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTS	PR00824. HEPLIPASE. PR00821. TAGLIPASE.
SMART	SM00308. LH2. 1 hit. [Graphical view]
SUPFAM	SSF49723. Lipase_LipOase. 1 hit.
PROSITE	PS50095. PLAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F1N3X6_BOVIN

Accession

Primary (citable) accession number: F1N3X6

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	November 16, 2011
Last modified:	March 6, 2013
This is version 16 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)