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F1MZL4

- F1MZL4_BOVIN

UniProt

F1MZL4 - F1MZL4_BOVIN

Protein
Submitted name:

Uncharacterized protein

Gene

REN

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. aspartic-type endopeptidase activity Source: UniProtKB-KW

    GO - Biological processi

    1. angiotensin maturation Source: Ensembl
    2. cell maturation Source: Ensembl
    3. drinking behavior Source: Ensembl
    4. hormone-mediated signaling pathway Source: Ensembl
    5. male gonad development Source: Ensembl
    6. mesonephros development Source: Ensembl
    7. regulation of MAPK cascade Source: Ensembl
    8. renin-angiotensin regulation of aldosterone production Source: Ensembl

    Keywords - Molecular functioni

    Aspartyl proteaseUniRule annotation, Hydrolase, Protease

    Enzyme and pathway databases

    ReactomeiREACT_203928. Metabolism of Angiotensinogen to Angiotensins.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:RENImported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 16

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl
    2. intracellular Source: Ensembl

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase A1 family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00710000106265.
    OMAiIARYYTE.
    OrthoDBiEOG7HQN88.
    TreeFamiTF314990.

    Family and domain databases

    Gene3Di2.40.70.10. 2 hits.
    InterProiIPR001461. Aspartic_peptidase.
    IPR001969. Aspartic_peptidase_AS.
    IPR012848. Aspartic_peptidase_N.
    IPR021109. Peptidase_aspartic_dom.
    [Graphical view]
    PANTHERiPTHR13683. PTHR13683. 1 hit.
    PfamiPF07966. A1_Propeptide. 1 hit.
    PF00026. Asp. 1 hit.
    [Graphical view]
    PRINTSiPR00792. PEPSIN.
    SUPFAMiSSF50630. SSF50630. 1 hit.
    PROSITEiPS00141. ASP_PROTEASE. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    F1MZL4-1 [UniParc]FASTAAdd to Basket

    « Hide

    VDQCSKMPLW GLLLVLWGSC TFSLPADTAA FRRIFLKKMP SVRESLKERG    50
    VDMARLGAEW SQLTKTLSFG NRTSPVVLTN YLDTQYYGEI GIGTPPQTFK 100
    VVFDTGSANL WVPSTKCSPL YTACEIHSLY DSLESSSYVE NGTEFTIHYG 150
    SGKVKGFLSQ DLVTVGGITV TQTFGEVTEL PLLPFMLAKF DGVLGMGFPA 200
    QAVGGVTPVF DHILAQRVLT DDVFSVYYSR NSHLLGGEIV LGGSDPQYYQ 250
    ENFHYVSISK PGSWQIRMKG VSVRSTTLLC EEGCMVIVDT GASYISGPTS 300
    SLRLLMEALG AKELSIDKYV VNCNQMPTLP DISFHLGGKA YTLTSADYVL 350
    QDPYNNDDLC TLALHGMDIP PPTGPVWVLG ATFIRKFYTE FDRRNNRIGF 400
    ALAR 404
    Length:404
    Mass (Da):44,462
    Last modified:May 3, 2011 - v1
    Checksum:i1CEDEF7917C49EEC
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02041912 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSBTAT00000028438; ENSBTAP00000028438; ENSBTAG00000021333.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02041912 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000028438 ; ENSBTAP00000028438 ; ENSBTAG00000021333 .

    Phylogenomic databases

    GeneTreei ENSGT00710000106265.
    OMAi IARYYTE.
    OrthoDBi EOG7HQN88.
    TreeFami TF314990.

    Enzyme and pathway databases

    Reactomei REACT_203928. Metabolism of Angiotensinogen to Angiotensins.

    Family and domain databases

    Gene3Di 2.40.70.10. 2 hits.
    InterProi IPR001461. Aspartic_peptidase.
    IPR001969. Aspartic_peptidase_AS.
    IPR012848. Aspartic_peptidase_N.
    IPR021109. Peptidase_aspartic_dom.
    [Graphical view ]
    PANTHERi PTHR13683. PTHR13683. 1 hit.
    Pfami PF07966. A1_Propeptide. 1 hit.
    PF00026. Asp. 1 hit.
    [Graphical view ]
    PRINTSi PR00792. PEPSIN.
    SUPFAMi SSF50630. SSF50630. 1 hit.
    PROSITEi PS00141. ASP_PROTEASE. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiF1MZL4_BOVIN
    AccessioniPrimary (citable) accession number: F1MZL4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3