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F1MZL4

- F1MZL4_BOVIN

UniProt

F1MZL4 - F1MZL4_BOVIN

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Protein
Submitted name:

Uncharacterized protein

Gene

REN

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. aspartic-type endopeptidase activity Source: UniProtKB-KW

GO - Biological processi

  1. angiotensin maturation Source: Ensembl
  2. cell maturation Source: Ensembl
  3. drinking behavior Source: Ensembl
  4. hormone-mediated signaling pathway Source: Ensembl
  5. male gonad development Source: Ensembl
  6. mesonephros development Source: Ensembl
  7. regulation of MAPK cascade Source: Ensembl
  8. renin-angiotensin regulation of aldosterone production Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Aspartyl proteaseUniRule annotation, Hydrolase, Protease

Enzyme and pathway databases

ReactomeiREACT_203928. Metabolism of Angiotensinogen to Angiotensins.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:RENImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 16

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
  2. intracellular Source: Ensembl
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase A1 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118929.
InParanoidiF1MZL4.
OMAiIARYYTE.
OrthoDBiEOG7HQN88.
TreeFamiTF314990.

Family and domain databases

Gene3Di2.40.70.10. 2 hits.
InterProiIPR001461. Aspartic_peptidase.
IPR001969. Aspartic_peptidase_AS.
IPR012848. Aspartic_peptidase_N.
IPR021109. Peptidase_aspartic_dom.
[Graphical view]
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiPF07966. A1_Propeptide. 1 hit.
PF00026. Asp. 1 hit.
[Graphical view]
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiPS00141. ASP_PROTEASE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F1MZL4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
VDQCSKMPLW GLLLVLWGSC TFSLPADTAA FRRIFLKKMP SVRESLKERG
60 70 80 90 100
VDMARLGAEW SQLTKTLSFG NRTSPVVLTN YLDTQYYGEI GIGTPPQTFK
110 120 130 140 150
VVFDTGSANL WVPSTKCSPL YTACEIHSLY DSLESSSYVE NGTEFTIHYG
160 170 180 190 200
SGKVKGFLSQ DLVTVGGITV TQTFGEVTEL PLLPFMLAKF DGVLGMGFPA
210 220 230 240 250
QAVGGVTPVF DHILAQRVLT DDVFSVYYSR NSHLLGGEIV LGGSDPQYYQ
260 270 280 290 300
ENFHYVSISK PGSWQIRMKG VSVRSTTLLC EEGCMVIVDT GASYISGPTS
310 320 330 340 350
SLRLLMEALG AKELSIDKYV VNCNQMPTLP DISFHLGGKA YTLTSADYVL
360 370 380 390 400
QDPYNNDDLC TLALHGMDIP PPTGPVWVLG ATFIRKFYTE FDRRNNRIGF

ALAR
Length:404
Mass (Da):44,462
Last modified:May 3, 2011 - v1
Checksum:i1CEDEF7917C49EEC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02041912 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSBTAT00000028438; ENSBTAP00000028438; ENSBTAG00000021333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02041912 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000028438 ; ENSBTAP00000028438 ; ENSBTAG00000021333 .

Phylogenomic databases

GeneTreei ENSGT00760000118929.
InParanoidi F1MZL4.
OMAi IARYYTE.
OrthoDBi EOG7HQN88.
TreeFami TF314990.

Enzyme and pathway databases

Reactomei REACT_203928. Metabolism of Angiotensinogen to Angiotensins.

Family and domain databases

Gene3Di 2.40.70.10. 2 hits.
InterProi IPR001461. Aspartic_peptidase.
IPR001969. Aspartic_peptidase_AS.
IPR012848. Aspartic_peptidase_N.
IPR021109. Peptidase_aspartic_dom.
[Graphical view ]
PANTHERi PTHR13683. PTHR13683. 1 hit.
Pfami PF07966. A1_Propeptide. 1 hit.
PF00026. Asp. 1 hit.
[Graphical view ]
PRINTSi PR00792. PEPSIN.
SUPFAMi SSF50630. SSF50630. 1 hit.
PROSITEi PS00141. ASP_PROTEASE. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiF1MZL4_BOVIN
AccessioniPrimary (citable) accession number: F1MZL4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3