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F1MW44

- F1MW44_BOVIN

UniProt

F1MW44 - F1MW44_BOVIN

Protein
Submitted name:

Coagulation factor XIII A chain

Gene

F13A1

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei315 – 3151UniRule annotation
    Active sitei374 – 3741UniRule annotation
    Active sitei397 – 3971UniRule annotation
    Metal bindingi437 – 4371CalciumUniRule annotation
    Metal bindingi439 – 4391CalciumUniRule annotation
    Metal bindingi486 – 4861CalciumUniRule annotation
    Metal bindingi491 – 4911CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. blood coagulation Source: Ensembl
    2. peptide cross-linking Source: Ensembl

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Coagulation factor XIII A chainImported
    Gene namesi
    Name:F13A1Imported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 23

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115156.
    KOiK03917.
    OMAiCEEDAVY.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F1MW44-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSESSGTAFG GRRAIPPNTS NAAENDPPTV ELQGLVPRGF NPQDYLNVTN    50
    VHLFKERWDS NKVDHHTDKY SNDKLIVRRG QSFYIQIDFN RPYDPTRDLF 100
    RVEYVIGLYP QENKGTYIPV PLVSELQSGK WGAKVVMRED RSVRLSVQSS 150
    ADCIVGKFRM YVAVWTPYGV IRTSRNPETD TYILFNPWCE EDAVYLENEK 200
    EREECVLNDI GVIFYGDFND IKSRSWSYGQ FEDSILDACL FVMDKANMDL 250
    SGRGNPIKVS RVGSAMINAK DDEGVIAGSW DNVYAYGVPP SAWTGSVDIL 300
    LEYKSSQKPV RYGQCWVFAG VFNTFLRCLG IPARVVTNYF SAHDNDANLQ 350
    LDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQVVDSTP 400
    QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL VYVTAKKDGT 450
    HVVEALDTTH IGKLIVTKEI GGDGMKDITD TYKFQEGQEE ERLALETAMM 500
    YGAKKALNTE GVLKSKSDVR MNFEVENAVL GRDLKVIITF RNNGSARYTV 550
    TAYLSGNISF YTGVSKAEFK NKTFEVTLEP LSFKREEVLI GAGEYMGQLL 600
    EQAFLHFFVT ARVNETRDVL AKQKSIALTV PKVVIKVRGA QVVGSDMVVT 650
    VEFTNPLKET LRNVWIRLDG PGVTKPLRKM FREIRPNSTV QWEELCRPWV 700
    SGPRKLIASL TSDSLRHVYG ELDLQIQRRP SM 732
    Length:732
    Mass (Da):82,675
    Last modified:May 3, 2011 - v1
    Checksum:i7C02DD47604BA08E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02055840 Genomic DNA. No translation available.
    DAAA02055841 Genomic DNA. No translation available.
    DAAA02055842 Genomic DNA. No translation available.
    DAAA02055843 Genomic DNA. No translation available.
    DAAA02055844 Genomic DNA. No translation available.
    DAAA02055845 Genomic DNA. No translation available.
    RefSeqiNP_001161366.1. NM_001167894.1.
    UniGeneiBt.19195.

    Genome annotation databases

    EnsembliENSBTAT00000009559; ENSBTAP00000009559; ENSBTAG00000007268.
    GeneIDi617881.
    KEGGibta:617881.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02055840 Genomic DNA. No translation available.
    DAAA02055841 Genomic DNA. No translation available.
    DAAA02055842 Genomic DNA. No translation available.
    DAAA02055843 Genomic DNA. No translation available.
    DAAA02055844 Genomic DNA. No translation available.
    DAAA02055845 Genomic DNA. No translation available.
    RefSeqi NP_001161366.1. NM_001167894.1.
    UniGenei Bt.19195.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000009559 ; ENSBTAP00000009559 ; ENSBTAG00000007268 .
    GeneIDi 617881.
    KEGGi bta:617881.

    Organism-specific databases

    CTDi 2162.

    Phylogenomic databases

    GeneTreei ENSGT00740000115156.
    KOi K03917.
    OMAi CEEDAVY.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Miscellaneous databases

    NextBioi 20900881.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiF1MW44_BOVIN
    AccessioniPrimary (citable) accession number: F1MW44
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3