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F1MW44

- F1MW44_BOVIN

UniProt

F1MW44 - F1MW44_BOVIN

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Protein
Submitted name:

Coagulation factor XIII A chain

Gene

F13A1

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei315 – 3151UniRule annotation
Active sitei374 – 3741UniRule annotation
Active sitei397 – 3971UniRule annotation
Metal bindingi437 – 4371CalciumUniRule annotation
Metal bindingi439 – 4391CalciumUniRule annotation
Metal bindingi486 – 4861CalciumUniRule annotation
Metal bindingi491 – 4911CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. blood coagulation Source: Ensembl
  2. peptide cross-linking Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII A chainImported
Gene namesi
Name:F13A1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 23

Subcellular locationi

GO - Cellular componenti

  1. blood microparticle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiF1MW44. baseline.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
KOiK03917.
OMAiCEEDAVY.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1MW44-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSESSGTAFG GRRAIPPNTS NAAENDPPTV ELQGLVPRGF NPQDYLNVTN
60 70 80 90 100
VHLFKERWDS NKVDHHTDKY SNDKLIVRRG QSFYIQIDFN RPYDPTRDLF
110 120 130 140 150
RVEYVIGLYP QENKGTYIPV PLVSELQSGK WGAKVVMRED RSVRLSVQSS
160 170 180 190 200
ADCIVGKFRM YVAVWTPYGV IRTSRNPETD TYILFNPWCE EDAVYLENEK
210 220 230 240 250
EREECVLNDI GVIFYGDFND IKSRSWSYGQ FEDSILDACL FVMDKANMDL
260 270 280 290 300
SGRGNPIKVS RVGSAMINAK DDEGVIAGSW DNVYAYGVPP SAWTGSVDIL
310 320 330 340 350
LEYKSSQKPV RYGQCWVFAG VFNTFLRCLG IPARVVTNYF SAHDNDANLQ
360 370 380 390 400
LDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQVVDSTP
410 420 430 440 450
QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL VYVTAKKDGT
460 470 480 490 500
HVVEALDTTH IGKLIVTKEI GGDGMKDITD TYKFQEGQEE ERLALETAMM
510 520 530 540 550
YGAKKALNTE GVLKSKSDVR MNFEVENAVL GRDLKVIITF RNNGSARYTV
560 570 580 590 600
TAYLSGNISF YTGVSKAEFK NKTFEVTLEP LSFKREEVLI GAGEYMGQLL
610 620 630 640 650
EQAFLHFFVT ARVNETRDVL AKQKSIALTV PKVVIKVRGA QVVGSDMVVT
660 670 680 690 700
VEFTNPLKET LRNVWIRLDG PGVTKPLRKM FREIRPNSTV QWEELCRPWV
710 720 730
SGPRKLIASL TSDSLRHVYG ELDLQIQRRP SM
Length:732
Mass (Da):82,675
Last modified:May 3, 2011 - v1
Checksum:i7C02DD47604BA08E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02055840 Genomic DNA. No translation available.
DAAA02055841 Genomic DNA. No translation available.
DAAA02055842 Genomic DNA. No translation available.
DAAA02055843 Genomic DNA. No translation available.
DAAA02055844 Genomic DNA. No translation available.
DAAA02055845 Genomic DNA. No translation available.
RefSeqiNP_001161366.1. NM_001167894.1.
UniGeneiBt.19195.

Genome annotation databases

EnsembliENSBTAT00000009559; ENSBTAP00000009559; ENSBTAG00000007268.
GeneIDi617881.
KEGGibta:617881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DAAA02055840 Genomic DNA. No translation available.
DAAA02055841 Genomic DNA. No translation available.
DAAA02055842 Genomic DNA. No translation available.
DAAA02055843 Genomic DNA. No translation available.
DAAA02055844 Genomic DNA. No translation available.
DAAA02055845 Genomic DNA. No translation available.
RefSeqi NP_001161366.1. NM_001167894.1.
UniGenei Bt.19195.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000009559 ; ENSBTAP00000009559 ; ENSBTAG00000007268 .
GeneIDi 617881.
KEGGi bta:617881.

Organism-specific databases

CTDi 2162.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
KOi K03917.
OMAi CEEDAVY.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Miscellaneous databases

NextBioi 20900881.

Gene expression databases

ExpressionAtlasi F1MW44. baseline.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiF1MW44_BOVIN
AccessioniPrimary (citable) accession number: F1MW44
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3