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Protein
Submitted name:

Coagulation factor XIII A chain

Gene

F13A1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei315UniRule annotation1
Active sitei374UniRule annotation1
Active sitei397UniRule annotation1
Metal bindingi437CalciumUniRule annotation1
Metal bindingi439CalciumUniRule annotation1
Metal bindingi486CalciumUniRule annotation1
Metal bindingi491CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiR-BTA-114608 Platelet degranulation
R-BTA-140875 Common Pathway of Fibrin Clot Formation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII A chainImported
Gene namesi
Name:F13A1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 23

Organism-specific databases

VGNCiVGNC:28680 F13A1

PTM / Processingi

Proteomic databases

PRIDEiF1MW44

Expressioni

Gene expression databases

BgeeiENSBTAG00000007268

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini307 – 400TGcInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
KOiK03917
OMAiCEEDAVY
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR034810 Factor_XIII_A
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PANTHERiPTHR11590:SF42 PTHR11590:SF42, 1 hit
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

F1MW44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESSGTAFG GRRAIPPNTS NAAENDPPTV ELQGLVPRGF NPQDYLNVTN
60 70 80 90 100
VHLFKERWDS NKVDHHTDKY SNDKLIVRRG QSFYIQIDFN RPYDPTRDLF
110 120 130 140 150
RVEYVIGLYP QENKGTYIPV PLVSELQSGK WGAKVVMRED RSVRLSVQSS
160 170 180 190 200
ADCIVGKFRM YVAVWTPYGV IRTSRNPETD TYILFNPWCE EDAVYLENEK
210 220 230 240 250
EREECVLNDI GVIFYGDFND IKSRSWSYGQ FEDSILDACL FVMDKANMDL
260 270 280 290 300
SGRGNPIKVS RVGSAMINAK DDEGVIAGSW DNVYAYGVPP SAWTGSVDIL
310 320 330 340 350
LEYKSSQKPV RYGQCWVFAG VFNTFLRCLG IPARVVTNYF SAHDNDANLQ
360 370 380 390 400
LDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQVVDSTP
410 420 430 440 450
QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL VYVTAKKDGT
460 470 480 490 500
HVVEALDTTH IGKLIVTKEI GGDGMKDITD TYKFQEGQEE ERLALETAMM
510 520 530 540 550
YGAKKALNTE GVLKSKSDVR MNFEVENAVL GRDLKVIITF RNNGSARYTV
560 570 580 590 600
TAYLSGNISF YTGVSKAEFK NKTFEVTLEP LSFKREEVLI GAGEYMGQLL
610 620 630 640 650
EQAFLHFFVT ARVNETRDVL AKQKSIALTV PKVVIKVRGA QVVGSDMVVT
660 670 680 690 700
VEFTNPLKET LRNVWIRLDG PGVTKPLRKM FREIRPNSTV QWEELCRPWV
710 720 730
SGPRKLIASL TSDSLRHVYG ELDLQIQRRP SM
Length:732
Mass (Da):82,675
Last modified:May 3, 2011 - v1
Checksum:i7C02DD47604BA08E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02055840 Genomic DNA No translation available.
DAAA02055841 Genomic DNA No translation available.
DAAA02055842 Genomic DNA No translation available.
DAAA02055843 Genomic DNA No translation available.
DAAA02055844 Genomic DNA No translation available.
DAAA02055845 Genomic DNA No translation available.
RefSeqiNP_001161366.1, NM_001167894.1
UniGeneiBt.19195

Genome annotation databases

EnsembliENSBTAT00000009559; ENSBTAP00000009559; ENSBTAG00000007268
GeneIDi617881
KEGGibta:617881

Similar proteinsi

Entry informationi

Entry nameiF1MW44_BOVIN
AccessioniPrimary (citable) accession number: F1MW44
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 25, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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