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Protein
Submitted name:

Ectonucleotide pyrophosphatase/phosphodiesterase 1

Gene

ENPP1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-BTA-196843. Vitamin B2 (riboflavin) metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Ectonucleotide pyrophosphatase/phosphodiesterase 1Imported
Gene namesi
Name:ENPP1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei77 – 97HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1MNS5.

Expressioni

Gene expression databases

BgeeiENSBTAG00000021830.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000053402.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 144SMBInterPro annotationAdd BLAST41
Domaini145 – 189SMBInterPro annotationAdd BLAST45

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2645. Eukaryota.
COG1524. LUCA.
GeneTreeiENSGT00760000119157.
InParanoidiF1MNS5.
KOiK01513.
OMAiHFFIVLT.
OrthoDBiEOG091G017X.
TreeFamiTF330032.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiView protein in InterPro
IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR001604. DNA/RNA_non-sp_Endonuclease.
IPR020821. Extracellular_endonuc_su_A.
IPR002591. Phosphodiest/P_Trfase.
IPR036024. Somatomedin_B-like_dom.
IPR020436. Somatomedin_B_chordata.
IPR001212. Somatomedin_B_dom.
PfamiView protein in Pfam
PF01223. Endonuclease_NS. 1 hit.
PF01663. Phosphodiest. 1 hit.
PF01033. Somatomedin_B. 2 hits.
PRINTSiPR00022. SOMATOMEDINB.
SMARTiView protein in SMART
SM00892. Endonuclease_NS. 1 hit.
SM00477. NUC. 1 hit.
SM00201. SO. 2 hits.
SUPFAMiSSF53649. SSF53649. 1 hit.
SSF90188. SSF90188. 2 hits.
PROSITEiView protein in PROSITE
PS00524. SMB_1. 1 hit.
PS50958. SMB_2. 2 hits.

Sequencei

Sequence statusi: Complete.

F1MNS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERDSCAGGG SRGGEGGRGP REGLAGNGRD PGPGRAAEAS GEPQAAASLL
60 70 80 90 100
APMDLGEEPL ERAARARPAK DPNTYKVLSL VLSVCVLTTI LGCIFGLKPS
110 120 130 140 150
CAKEIKSCKG RCFERTFGNC RCDAACVDLG NCCLDYQETC IEPERIWTCT
160 170 180 190 200
KFRCGEKRLS RSLCSCSDDC KDKGDCCINH GSVCRGEKSW AEEECDSIDE
210 220 230 240 250
PQCPAGFETP PTLLFSLDGF RAEYLHTWGG LLPVISKLKT CGTYTKNMRP
260 270 280 290 300
VYPTKTFPNH YSIVTGLYPE SHGIIDNNIY DPQMNANFAL KNKEKFNPEW
310 320 330 340 350
YKGEPIWLTA KYQGLKTGTF FWPGSDVKIN GIFPDIYKIY NVSVPFEERI
360 370 380 390 400
LAILKWLQLP KDERPHFYTL YLEEPDSSGH SYGPVSSEVI RALQRVDNMV
410 420 430 440 450
GMLMDGLKEL NLHRCLNLIL ISDHGMEQGS CKKYVYLNKY LGDTKDYKVV
460 470 480 490 500
YGPAARLRPS DVPDKYYSFD YEGIAKNLSC QEPNQHFKPY LKHFLPKRLH
510 520 530 540 550
FAKNDRIERL TFYLDPQWQL ALNPSERKYC GGGFHGSDNT FLNMQALFIG
560 570 580 590 600
YGPGFKHSTE VDSFENIEVY NLMCDLLNLT PAPNNGTHGS LNHLLSNPVY
610 620 630 640 650
TPKHPKEVRP LVQCPFTRAP RESLDCSCDP SILPIVDFQT QLNLTMAEEK
660 670 680 690 700
TIKRGALPYG RPRVLQNSTV CLLYQHQFVS GYSRDILMPL WTSYTIGRND
710 720 730 740 750
SFSTEDFSNC LYQDLRIPLS PVHKCSFYKN NAKLSYGLLS PPQLHKGSSQ
760 770 780 790 800
VYSEALLTTN IVPMYQSFQV IWHYLHGTLL QRYAEERNGL NVVSGPVFDS
810 820 830 840 850
DYDGRYDSLE TLKQNSKIIR NLEVLIPTHF FLVLTSCKNT SQTPLQCENL
860 870 880 890 900
DAMAFILPHK TDNSESCAHG KHESLWVEEL LKLHTARITD VEHITGLSFY
910 920
QERKEPISDI LKLKTHLPTF NQED
Length:924
Mass (Da):104,388
Last modified:May 3, 2011 - v1
Checksum:iD930ACE117B5908C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02026647 Genomic DNA. No translation available.
RefSeqiNP_001193141.1. NM_001206212.1.
UniGeneiBt.60975.

Genome annotation databases

EnsembliENSBTAT00000061365; ENSBTAP00000053402; ENSBTAG00000021830.
GeneIDi615535.
KEGGibta:615535.

Similar proteinsi

Entry informationi

Entry nameiF1MNS5_BOVIN
AccessioniPrimary (citable) accession number: F1MNS5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 25, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported