F1MLY7 (F1MLY7_BOVIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSBTAP00000015321

Gene names

Name:

ATR Ensembl ENSBTAP00000015321

Organism

Bos taurus (Bovine) [Reference proteome] Ensembl ENSBTAP00000015321

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	2626 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 FAT domain. SAAS SAAS018936 Contains 1 FATC domain. SAAS SAAS018936 Contains 1 PI3K/PI4K domain. SAAS SAAS018936
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSBTAP00000015321

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS018936 Nucleotide-binding
Molecular function	Kinase SAAS SAAS018936 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA damage checkpoint Inferred from electronic annotation. Source: Compara DNA repair Inferred from electronic annotation. Source: Compara cellular response to UV Inferred from electronic annotation. Source: Compara cellular response to gamma radiation Inferred from electronic annotation. Source: Compara negative regulation of DNA replication Inferred from electronic annotation. Source: Compara peptidyl-serine phosphorylation Inferred from electronic annotation. Source: Compara positive regulation of DNA damage response, signal transduction by p53 class mediator Inferred from electronic annotation. Source: Compara protein autophosphorylation Inferred from electronic annotation. Source: Compara regulation of protein binding Inferred from electronic annotation. Source: Compara replicative senescence Inferred from electronic annotation. Source: Compara
Cellular_component	XY body Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSBTAP00000015321

Sequences

	Sequence		Length	Mass (Da)
	F1MLY7 [UniParc]. Last modified November 16, 2011. Version 2. Checksum: 2225EE52BCC4351C	FASTA	2,626	299,728
	10 20 30 40 50 60 SASPEEYNTV VQKPRQILCQ FIDRILTDVN VVALELVKKT DSQPTSVMLL DFIQHIMKSS 70 80 90 100 110 120 PLMFVNVNGS HGQNEAKGSC IEFSNWIITR LLRIAATPSC HMLHKKICEV ICALLFLFKS 130 140 150 160 170 180 KSPAIFGVLM KELLHLFEDL IYFHKRYAVE HFVEWPVVVH RFLSQFDEHV GYLQPAPLQL 190 200 210 220 230 240 MNMQNLEFIE VTLLTVLIRI IAIVFFRRQE LLLWQIGCVL LEYGSPKVKS LAISLLTELF 250 260 270 280 290 300 ELGGLPAQPA STFFSSFFEL LKQLVEMDAD QLKLYEEPLS KLIKTLFSSE TEAYRNIEPV 310 320 330 340 350 360 YLNMLLEKLC VMFEDGVLLQ LKSDLLKAAL CHLLQYFLKY VPAGYESALQ VRKVYMRNIC 370 380 390 400 410 420 KALVDVLGVQ ADVEYLLGPL YAALKMESME IIDEVQCQIQ QEDLSSNSNG LSPKRRRLSS 430 440 450 460 470 480 SLNASKRAPK QTEEIKHVDI NKKSILWSAL KQKAEDLQIF LESNNVKNPI IETLEGIAVI 490 500 510 520 530 540 LQLTALCTVH CSHQNMDCYN FKDCQQKCKK KPSVMITWMS VDFYTKVLKS CRTLLESVQK 550 560 570 580 590 600 PDLETVIDKV VKIYDALMYI QVNTSFEDHI LEDLCGMLSL PWICLHSDDD SLKLTTFALS 610 620 630 640 650 660 LLTLSQRISD SYSPQAQSRC VFLLTLFPRR IHLEWRTAVY SWALQSSHEV IRTSCINGFF 670 680 690 700 710 720 ILLQQQNPYN RVPKILVDKV KDDSDIVKKE FASVLGQLVC TLHGKFYLTS SLTEPLSEYG 730 740 750 760 770 780 HIDLLCKSLK VASQPECSSS RLKASVCKPF LFLLKKKTPS PVKLAFIENL HHLCKHLDFR 790 800 810 820 830 840 EDETDIKTVL GTLLNLMEDP DKDVRVAFSG NIKHILESLD AEDGFIKELF VLRMKEAYTH 850 860 870 880 890 900 AQISRNNELK DTLILTTGDI GRAAKGDLVP FALLHLLHCL LSKSASVSGA AYTEIRALVA 910 920 930 940 950 960 AKSVKLQNFF SQYKKPICQF LVESLHSSQM TALPSTPCQN AEMRKQDVAH QREMALNTLS 970 980 990 1000 1010 1020 EIANVFDFPD LNRFLTRTLQ VLLPDLAAKA SPAASALIRT LGKQLNVNRR EILINNFKYI 1030 1040 1050 1060 1070 1080 FSHLVCSCSK DELERALHYL KNETEIELGS LLRQDFQGLH NELLLRIGEH YQQVFNGLSI 1090 1100 1110 1120 1130 1140 LASFASSDDP YQGPRDITSP ELMADYLQPK LLGILAFFNM QLLSSSVGIE DKKMALNSLM 1150 1160 1170 1180 1190 1200 SLMKLMGPKH VSSVRVKMMT TLRTGLRFKD DFPELCCRAW DCFVRCLDHA YLGSLLSHVI 1210 1220 1230 1240 1250 1260 VALLPLIHIQ PKETAAIFHY LIIENRDAVQ DFLHEIYFLP DHQELKKIKA VLQEYRKETS 1270 1280 1290 1300 1310 1320 ESTDLQTTLQ LSMKAIQHEN VDVRIHALTS LKETLYKNQE KLIRYATDSE TVEPVISQLV 1330 1340 1350 1360 1370 1380 TVLLKGCQDA NSQARLLCGE CLGELGAIDP GRLDFSTTDT QGKDFTFVTG VEDSNFAYGL 1390 1400 1410 1420 1430 1440 LMELTRAYLA YADNSRAQDS AAYAIQELLS IYDCREMQTD GPGHQLWRRF PEHVREILEP 1450 1460 1470 1480 1490 1500 HLNTRYKSSQ KSTDWSGVKK PIYLSKLGNN FAEWSASWAG YLITKVRHDL ASKIFTCCSI 1510 1520 1530 1540 1550 1560 MMKHDFKVTI YLLPHILVYV LLGCNQEDRQ EVYAEIMAVL KHDDHHTLST QDSASDLCQL 1570 1580 1590 1600 1610 1620 STQTVFSMLD HLTQWARHKF QALNAEKFAQ GKSHRDKVDS MVSSVDYEDY QSVTRFLDLI 1630 1640 1650 1660 1670 1680 PQDTLAVASF RSKAYTRAVM HFESFITEKK QNIQEHLGFL QKLYAAMHEP DGVAGVSAIR 1690 1700 1710 1720 1730 1740 KAEPSLKEQI LEHESIGLLR DATACYDRAI QLEPDQIIHY HGVVKSMLGL GQLSTVITQV 1750 1760 1770 1780 1790 1800 NGVHANSRSE WTDELNTYRV EAAWKLSQWD LVENYLAADG KSTTWSVRLG QLLLSAKKRD 1810 1820 1830 1840 1850 1860 TTAFYDTLKL VRAEQIVPLS AASFERGSYQ RGYEYIVRLH MLCELEHSIK PLFHQSPADS 1870 1880 1890 1900 1910 1920 IQEDSLNWVA RLEMTQNSYR AKEPILALRR ALLSLNKRPD YSEMVGECWL QSARVARKAG 1930 1940 1950 1960 1970 1980 HHQTAYNALL NAGDSRLAEL YVERAKWLWS KGDVHQALIV LQKGVELCFP ENKTPPEGKN 1990 2000 2010 2020 2030 2040 MLIHGRATLL VGRFMEETAN FESNAVMKKY KDVTLFLPEW EDGHFYLAKY YDKLMPMVTD 2050 2060 2070 2080 2090 2100 NKMEKQGDLI RYILLHFGRS LQYGNQFIYQ SMPRMLSLWL DFGAKAYEWE KAGRSDRVQM 2110 2120 2130 2140 2150 2160 RNDLVKINKV ITEHTNQLAP YQFLTAFSQL ISRICHSHDE VFVVLMEIIA KVLLAYPQQA 2170 2180 2190 2200 2210 2220 MWMMTAVSKS SYPMRVNRCK EILNKAIQMK KSLEKFVGDA TRLTDKLLEL CNKSVDGSSS 2230 2240 2250 2260 2270 2280 TLSMSTHFKM LKKLVEEATF SEILIPLQSV MIPTLPSIPG AHANHEPFPG HWAYIAGFDD 2290 2300 2310 2320 2330 2340 TVEILASLQK PKKISLKGSD GKFYIMMCKP KDDLRKDCRL MEFNSLINKC LRKDAESRRR 2350 2360 2370 2380 2390 2400 ELHIRTYAVI PLNDECGIIE WVNNTAGLRP ILTKLYKEKG VYMTGKELRQ CMLPKSAALS 2410 2420 2430 2440 2450 2460 EKLKVFQEFL LPRHPPVFHE WFLRTFPDPT SWYSSRSAYC RSTAVMSMVG YILGLGDRHG 2470 2480 2490 2500 2510 2520 ENILFDSLTG ECVHVDFNCL FNKGETFEVP EIVPFRLTHN MVNGMGPMGT EGLFRRACEV 2530 2540 2550 2560 2570 2580 TMRLMRDQRE PLMSVLKTFL HDPLVEWSKP VKGHSKAALN ETGEVVNEKA KTHVLDIEQR 2590 2600 2610 2620 LRGVIKTRNR VTGLPLSIEG HVHYLIQEAT DENLLCQMYL GWTPYM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol. 10:R42-R42(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hereford Ensembl ENSBTAP00000015321.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Hereford Ensembl ENSBTAP00000015321.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DAAA02002874 Genomic DNA. No translation available. DAAA02002875 Genomic DNA. No translation available.
IPI	IPI01001317.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000015321; ENSBTAP00000015321; ENSBTAG00000011529.
Phylogenomic databases
GeneTree	ENSGT00690000102233.
OMA	AIQHENV.
Family and domain databases
Gene3D	1.10.1070.11. 2 hits. 1.25.10.10. 3 hits. 1.25.40.10. 3 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR003152. FATC. IPR021133. HEAT_type_2. IPR011009. Kinase-like_dom. IPR000403. PI3/4_kinase_cat_dom. IPR018936. PI3/4_kinase_CS. IPR003151. PIK-rel_kinase_FAT. IPR014009. PIK_FAT. IPR011990. TPR-like_helical. IPR012993. UME. [Graphical view]
Pfam	PF02259. FAT. 1 hit. PF02260. FATC. 1 hit. PF00454. PI3_PI4_kinase. 1 hit. PF08064. UME. 1 hit. [Graphical view]
SMART	SM00146. PI3Kc. 1 hit. SM00802. UME. 1 hit. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit. SSF56112. Kinase_like. 1 hit.
PROSITE	PS51189. FAT. 1 hit. PS51190. FATC. 1 hit. PS50077. HEAT_REPEAT. 1 hit. PS00916. PI3_4_KINASE_2. 1 hit. PS50290. PI3_4_KINASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F1MLY7_BOVIN

Accession

Primary (citable) accession number: F1MLY7

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	November 16, 2011
Last modified:	March 6, 2013
This is version 17 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)