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Protein
Submitted name:

Hexokinase domain containing 1

Gene

HKDC1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase domain containing 1Imported
Gene namesi
Name:HKDC1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1MIM3.

Expressioni

Gene expression databases

BgeeiENSBTAG00000033398.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000044680.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini470 – 666Hexokinase_1InterPro annotationAdd BLAST197
Domaini672 – 906Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
InParanoidiF1MIM3.
KOiK00844.
OMAiKIETRHV.
OrthoDBiEOG091G08MD.
TreeFamiTF314238.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
PROSITEiView protein in PROSITE
PS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 2 hits.

Sequencei

Sequence statusi: Complete.

F1MIM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAVHLMAFY FTKLKEDQIK KVDRFLYHMR LSDETLLDIM ARFQAEMQKG
60 70 80 90 100
LGKDTNPTAS VKMLPTFVRA IPDGSENGEF LSLDLGGSKF RVLKVQVSEE
110 120 130 140 150
GKRNVQMESQ FYPTPNEIIR GNGTELFEYV ADCLADFMKT KELMQKKLPL
160 170 180 190 200
GLTFSFPCKQ TKLEEGILLS WTKKFKARGV QGTDVVSSLT NAMKRHQDLD
210 220 230 240 250
VDILALVNDT VGTMMTCAYD DPYCEVGVII GTGTNACYME DMSNIDLVEG
260 270 280 290 300
DEGRMCVNTE WGAFGDDGAL EDIRTEFDRE LDLGSLNPGK QLFEKMISGL
310 320 330 340 350
YLGELVRLIL LKMAKAGLLF GGEKSSALHI KGKIETRHVA AMERYKEGLA
360 370 380 390 400
NTREILTDLG LEPSDADCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN
410 420 430 440 450
KKLVRLRTTV GVDGTLYKIH PQYPKRLHKV VRKLVPNCDV RFLLSESGST
460 470 480 490 500
KGAAMVTAVA SRLQAQRKQI DKVLALFRLT QEQLVGIRNK MRVEFEYGLK
510 520 530 540 550
KDTHPLATVK MLPTYVCGMP DGTEKGKFLA LDLGGTNFRV LLVKIRSGRR
560 570 580 590 600
SVRMYNKIFA IPLEIMQGTG EELFDHIVQC IADFLDYMGL KGAQLPLGFT
610 620 630 640 650
FSFPCRQANI DKGTLIEWTK GFKATDCEGE DVVDMLREAI KRRNEFDLDI
660 670 680 690 700
VAVVNDTVGT MMTCGYEDSN CEVGLIAGTG SNMCYMEEMR NIELVEGDEG
710 720 730 740 750
KMCINTEWGG FGDNGCLDDI HTQYDKEVDE GSLNPGKQRY EKMTSGMYLG
760 770 780 790 800
EIVRQILIDL TKQGLLFRGQ ISERLRTRGI FETKFLSQIE SDRLALLQVR
810 820 830 840 850
RILQQLGLDS TCEDSIVVKE VCGAVSRRAA QLYGAGLAAI VEKRREDQGL
860 870 880 890 900
EHMRITVGVD GTLYKLHPHF SRILRETVKE LAPQCDVMFM LSEDGSGKGA
910
ALITAVAKRL QQAQREH
Length:917
Mass (Da):102,579
Last modified:November 16, 2011 - v2
Checksum:iC6FA3C70CC00CFCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02061832 Genomic DNA. No translation available.
RefSeqiNP_001178413.1. NM_001191484.1.
UniGeneiBt.1522.

Genome annotation databases

EnsembliENSBTAT00000047474; ENSBTAP00000044680; ENSBTAG00000033398.
GeneIDi614824.
KEGGibta:614824.

Similar proteinsi

Entry informationi

Entry nameiF1MIM3_BOVIN
AccessioniPrimary (citable) accession number: F1MIM3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: November 16, 2011
Last modified: August 30, 2017
This is version 49 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported