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F1M888 (F1M888_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Rap guanine nucleotide exchange factor 5 Ensembl ENSRNOP00000007112
Gene names
Name:Rapgef5 Ensembl ENSRNOP00000007112 RGD 1561668
OrganismRattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000007112
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length580 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Sequence similarities

Contains 1 N-terminal Ras-GEF domain. SAAS SAAS000651

Contains 1 Ras-GEF domain. SAAS SAAS000651

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSRNOP00000007112

Sequences

Sequence LengthMass (Da)Tools
F1M888 [UniParc].

Last modified April 3, 2013. Version 2.
Checksum: 276AA76498458945

FASTA58067,585
        10         20         30         40         50         60 
MGSSRLRVFD PPLERKDSAA LSERQLPLPT FDVPYFKYID EEDEDDEWSS RSQSSTEDDS 

        70         80         90        100        110        120 
VDSLLSDRYV VVSGTPEKIL EHLLNDLHLA EVQHKETETL LDDFLLTYTV FMTTDDLCQA 

       130        140        150        160        170        180 
LLRHYSAKKY QGEEENSDVP CRKRKVLHLV SQWISLYKDW LHEDEHSKMF LKTIYRNVLD 

       190        200        210        220        230        240 
DVYEYPILEK ELKEFQKILG MHRRHTLALY SPQKKNKALF HQFSLKENWL QHRGTVAETE 

       250        260        270        280        290        300 
EIFCHVYVTE HSYISVKAKV SSTAQEILKV VAEKLQRAEE DLALVAIMFS GEKHEFQPND 

       310        320        330        340        350        360 
LAISKSLEAS GRIYVYRKDL ADTLNPFAEN EESQQRSMRI LGMNTWDLAL ELMSFDWSLF 

       370        380        390        400        410        420 
NSIHEQELIY FTFSRQGSGE HTVNLSLLLQ RCNEVQLWVA TEILLCSQLG KRVQLVKKFI 

       430        440        450        460        470        480 
KIAAHCKAQQ NLNSFFAIVM GLNTASVSRL SQTWEKIPGK FKKLFSELES LTDPSLNHKA 

       490        500        510        520        530        540 
YRDAFKKMKP PKIPFMPLLL KDVTFIHEGN KTFLDNLVNF EKLHMIADTV RTLRHCRTNQ 

       550        560        570        580 
FGSDMSPKEQ QELKSYVNHL YVIDSQQALF ELSHRLEPRA

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000007112.
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000007112.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AABR06046777 Genomic DNA. No translation available.
AABR06046778 Genomic DNA. No translation available.
AABR06046779 Genomic DNA. No translation available.
IPIIPI00417384.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000007112; ENSRNOP00000007112; ENSRNOG00000005271.

Organism-specific databases

RGD1561668. Rapgef5.

Phylogenomic databases

GeneTreeENSGT00560000077091.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
1.10.840.10. 1 hit.
InterProIPR000591. DEP_dom.
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR008937. Ras_GEF.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERPTHR23113. PTHR23113. 1 hit.
PfamPF00610. DEP. 1 hit.
PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view]
SMARTSM00049. DEP. 1 hit.
SM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
[Graphical view]
SUPFAMSSF48366. Ras_GEF. 1 hit.
PROSITEPS50186. DEP. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35582507.

Entry information

Entry nameF1M888_RAT
AccessionPrimary (citable) accession number: F1M888
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: May 1, 2013
This is version 18 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info