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Protein
Submitted name:

Tumor protein p53-binding protein 1

Gene

Tp53bp1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-3232118 SUMOylation of transcription factors
R-RNO-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
R-RNO-5693571 Nonhomologous End-Joining (NHEJ)
R-RNO-69473 G2/M DNA damage checkpoint

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor protein p53-binding protein 1Imported
Gene namesi
Name:Tp53bp1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1308039 Tp53bp1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1M842
PeptideAtlasiF1M842
PRIDEiF1M842

PTM databases

iPTMnetiF1M842
PhosphoSitePlusiF1M842

Expressioni

Gene expression databases

BgeeiENSRNOG00000013837

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiF1M842, 1 interactor
STRINGi10116.ENSRNOP00000019025

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1780 – 1848BRCTInterPro annotationAdd BLAST69
Domaini1864 – 1964BRCTInterPro annotationAdd BLAST101

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili129 – 149Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3548 Eukaryota
ENOG411075K LUCA
GeneTreeiENSGT00390000011891
InParanoidiF1M842
KOiK20915
OMAiCIDLTCD
OrthoDBiEOG091G0BHF
TreeFamiTF350227

Family and domain databases

CDDicd00027 BRCT, 2 hits
Gene3Di2.30.30.30, 1 hit
3.40.50.10190, 2 hits
InterProiView protein in InterPro
IPR015125 53-BP1_Tudor
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR014722 Rib_L2_dom2
PfamiView protein in Pfam
PF09038 53-BP1_Tudor, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 2 hits
SUPFAMiSSF52113 SSF52113, 2 hits
PROSITEiView protein in PROSITE
PS50172 BRCT, 2 hits

Sequencei

Sequence statusi: Complete.

F1M842-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGEQMDPTG SQLDSDFSQQ DTPCLIIEDS QPESQALEED AGSHFSVLSR
60 70 80 90 100
HLPNLQMHKE NPVLDIMSNP EQTVAEQGDS NSSFSEHLKE KKASDPVESS
110 120 130 140 150
HLGTSGPISQ VIERLPQPNR TSSALGVTVE AASLAEEEKE EELEEEKEEV
160 170 180 190 200
GVNAPDADPR SLAEDSASSQ LGFGVLELSQ SQDVEEHTVP YDVKQEHLQL
210 220 230 240 250
VTTNSGSTQL SDVDANTDGK AIKCEEQSTD AISIIEPSKD IPVTVQPSKG
260 270 280 290 300
SHVVEEQNLP LVRSEDLPSS PQVSVAAVET KEQVPAQELL EGGLQVQVSS
310 320 330 340 350
EPEVSSTQED LFDQSSKTAS DGCSTPSREE GGCSPVSTPA TTLQLLQLSG
360 370 380 390 400
QKPLVQESLS TNSSDLVAPS PDAFRSTPFI VPSSPTEQGQ RKDEPMDMSV
410 420 430 440 450
IPEGGEHFQK LQDDEAVDIE KPLLPSQPAV SPQASTPVSR STPVFTPASL
460 470 480 490 500
PIPSQPEFSH DIFIPSPSLE EPSNDVEKGG GLHSSSLTVE CSKTSESEPK
510 520 530 540 550
NFTDDLGLSM TGDSCKLMLS TSECSQSSKM ESLGSPRTEE VGENTQVEDT
560 570 580 590 600
EPSSPVTKSK LPAESESVLV NPTQDDQVEM SQNVDKAKED EVEDRGDVDV
610 620 630 640 650
LAAGCKGRED MVAEDVCIDL TCDSGSQAVP SPATRSEALS SVLDQEEAME
660 670 680 690 700
IKEHHPEEEF SGSEVEEVPE TPCGSHREES KEEPMESIPL HLSLTETQSE
710 720 730 740 750
ALCLQKEAPK EECPEAMEVE TSVISIDSPQ KLPVLDQELE HKDPETWEEA
760 770 780 790 800
TSEDSSVVIV DVKEPSPRVD ISCEPVEGVG KCSDSQSLEG AAPEEEPCAE
810 820 830 840 850
NRLNTPEEKR VECDGDSKAE TTEKNSVTED SPQPPLPSVR DEPVRPDQEL
860 870 880 890 900
QQPQVQEKES PVTLDAKVAD DKHLGSEGSC QQLEKAPARA SQSFCESSSE
910 920 930 940 950
TPFHFTLPKE GDIIPPLTGA TPPLIGHLKL EPKRHSTPIG ISNYPESTIA
960 970 980 990 1000
TSDVMSESMV EINDPLLGNE KGDSESAPEM DGKLSLKMKL VSPETEASEE
1010 1020 1030 1040 1050
SLQFSLEKPT TAERRNGSTA IAEPVASPQK PMSVFGCIYE AQQEEEAQSG
1060 1070 1080 1090 1100
DPPSTPVRTN LLHFPSAQEE DREEPDATPQ LRQSEQPVKL IGPVKDAAAS
1110 1120 1130 1140 1150
EDSASSVSQQ RASQGSLSPQ EEVMEADLLE GLGANQDRPS KILMERPTQS
1160 1170 1180 1190 1200
NIGIQTMDHS LCAPETVSAA TQTVKNVCEQ GTSTVEQNSG KQDATVQTER
1210 1220 1230 1240 1250
GSGEKPASAP VDDTESLHSQ GEEEFEMPQP PHGHVLHRHT RTIREVRTLV
1260 1270 1280 1290 1300
TRVITDVYYV DGTEVERKVT EETEEPIVEC QECETEVSPS QTGGSSGDLG
1310 1320 1330 1340 1350
DISSFSSKAS SSHHTSSGTS LSAIHSSGSS GRGAGPLKGK TSGTEPADFA
1360 1370 1380 1390 1400
LPSSRGGPGK LSPRKGISQT GAPVCEEDGD AGLGIRQGGK APVTPRGRGR
1410 1420 1430 1440 1450
RGRPPSRTTG TRETVVSGPL GIEDTSPSMS PDDKSFTRIM PRVPDSTKRM
1460 1470 1480 1490 1500
DASSGALRRS DSPEIPFQAA TGSSDGLDSS SSGNSFVGLR VVAKWSSNGY
1510 1520 1530 1540 1550
FYSGKITRDV GAGKYKLLFD DGYECDVLGK DILLCDPIPL DTEVTALSED
1560 1570 1580 1590 1600
EYFSAGVVKG HRKESGELYY SIEKEGQRKW YKRMAVILSL EQGNRLREQY
1610 1620 1630 1640 1650
GLGPYEAVTP LTKAADISLD NLVEGKRKRR SNISSPATPT ASSSSSTTPT
1660 1670 1680 1690 1700
RKTTESPRAS MGVPSGKRKL TTSEEERSPA KRGRKSATVK PGTVGAAELV
1710 1720 1730 1740 1750
SPCESGDNTG EPSVLEEPRG PLPLNKTLFL GYAFLLTMAT TSDKLASRSK
1760 1770 1780 1790 1800
LLDGPTGSSE EEEEFLEIPP FNKQYTECQL RAGAGYILED FNEAQCNTAY
1810 1820 1830 1840 1850
QCLLIADQHC RTRKYFLCLA SGIPCVSHVW VHDSCHANQL QNYRNYLLPA
1860 1870 1880 1890 1900
GYSLEEQRIL DWQPRENPFQ NLKVLLVSDQ QQNFLELWSE ILMTGGAASV
1910 1920 1930 1940 1950
KQHHSSAHNK DIALGVFDVV VTDPSCPASV LKCAEALQLP VVSQEWVIQC
1960 1970
LIVGERIGFQ QHPKYKHDYV SH
Length:1,972
Mass (Da):212,859
Last modified:July 22, 2015 - v3
Checksum:i660B61314249A379
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116071 Genomic DNA No translation available.
RefSeqiXP_006234927.1, XM_006234865.3
XP_008760428.1, XM_008762206.2
XP_017447703.1, XM_017592214.1
XP_017447704.1, XM_017592215.1

Genome annotation databases

EnsembliENSRNOT00000019025; ENSRNOP00000019025; ENSRNOG00000013837
GeneIDi296099
KEGGirno:296099

Similar proteinsi

Entry informationi

Entry nameiF1M842_RAT
AccessioniPrimary (citable) accession number: F1M842
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 22, 2015
Last modified: May 23, 2018
This is version 56 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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