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Protein
Submitted name:

Protein Tp53bp1

Gene

Tp53bp1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-3232118. SUMOylation of transcription factors.
R-RNO-5693565. Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
R-RNO-5693571. Nonhomologous End-Joining (NHEJ).
R-RNO-5693607. Processing of DNA double-strand break ends.
R-RNO-69473. G2/M DNA damage checkpoint.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Tp53bp1Imported
Gene namesi
Name:Tp53bp1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1308039. Tp53bp1.

Subcellular locationi

GO - Cellular componenti

  • chromosome, telomeric region Source: Ensembl
  • cytoplasm Source: Ensembl
  • nucleus Source: RGD
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiF1M842.
PeptideAtlasiF1M842.

PTM databases

iPTMnetiF1M842.
PhosphoSiteiF1M842.

Expressioni

Gene expression databases

BgeeiENSRNOG00000013837.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019025.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1780 – 184869BRCTInterPro annotationAdd
BLAST
Domaini1864 – 1964101BRCTInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3548. Eukaryota.
ENOG411075K. LUCA.
GeneTreeiENSGT00390000011891.
InParanoidiF1M842.
OMAiCIDLTCD.
OrthoDBiEOG091G0BHF.
TreeFamiTF350227.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR015125. 53-BP1_Tudor.
IPR001357. BRCT_dom.
IPR014722. Rib_L2_dom2.
[Graphical view]
PfamiPF09038. 53-BP1_Tudor. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 2 hits.
PROSITEiPS50172. BRCT. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1M842-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGEQMDPTG SQLDSDFSQQ DTPCLIIEDS QPESQALEED AGSHFSVLSR
60 70 80 90 100
HLPNLQMHKE NPVLDIMSNP EQTVAEQGDS NSSFSEHLKE KKASDPVESS
110 120 130 140 150
HLGTSGPISQ VIERLPQPNR TSSALGVTVE AASLAEEEKE EELEEEKEEV
160 170 180 190 200
GVNAPDADPR SLAEDSASSQ LGFGVLELSQ SQDVEEHTVP YDVKQEHLQL
210 220 230 240 250
VTTNSGSTQL SDVDANTDGK AIKCEEQSTD AISIIEPSKD IPVTVQPSKG
260 270 280 290 300
SHVVEEQNLP LVRSEDLPSS PQVSVAAVET KEQVPAQELL EGGLQVQVSS
310 320 330 340 350
EPEVSSTQED LFDQSSKTAS DGCSTPSREE GGCSPVSTPA TTLQLLQLSG
360 370 380 390 400
QKPLVQESLS TNSSDLVAPS PDAFRSTPFI VPSSPTEQGQ RKDEPMDMSV
410 420 430 440 450
IPEGGEHFQK LQDDEAVDIE KPLLPSQPAV SPQASTPVSR STPVFTPASL
460 470 480 490 500
PIPSQPEFSH DIFIPSPSLE EPSNDVEKGG GLHSSSLTVE CSKTSESEPK
510 520 530 540 550
NFTDDLGLSM TGDSCKLMLS TSECSQSSKM ESLGSPRTEE VGENTQVEDT
560 570 580 590 600
EPSSPVTKSK LPAESESVLV NPTQDDQVEM SQNVDKAKED EVEDRGDVDV
610 620 630 640 650
LAAGCKGRED MVAEDVCIDL TCDSGSQAVP SPATRSEALS SVLDQEEAME
660 670 680 690 700
IKEHHPEEEF SGSEVEEVPE TPCGSHREES KEEPMESIPL HLSLTETQSE
710 720 730 740 750
ALCLQKEAPK EECPEAMEVE TSVISIDSPQ KLPVLDQELE HKDPETWEEA
760 770 780 790 800
TSEDSSVVIV DVKEPSPRVD ISCEPVEGVG KCSDSQSLEG AAPEEEPCAE
810 820 830 840 850
NRLNTPEEKR VECDGDSKAE TTEKNSVTED SPQPPLPSVR DEPVRPDQEL
860 870 880 890 900
QQPQVQEKES PVTLDAKVAD DKHLGSEGSC QQLEKAPARA SQSFCESSSE
910 920 930 940 950
TPFHFTLPKE GDIIPPLTGA TPPLIGHLKL EPKRHSTPIG ISNYPESTIA
960 970 980 990 1000
TSDVMSESMV EINDPLLGNE KGDSESAPEM DGKLSLKMKL VSPETEASEE
1010 1020 1030 1040 1050
SLQFSLEKPT TAERRNGSTA IAEPVASPQK PMSVFGCIYE AQQEEEAQSG
1060 1070 1080 1090 1100
DPPSTPVRTN LLHFPSAQEE DREEPDATPQ LRQSEQPVKL IGPVKDAAAS
1110 1120 1130 1140 1150
EDSASSVSQQ RASQGSLSPQ EEVMEADLLE GLGANQDRPS KILMERPTQS
1160 1170 1180 1190 1200
NIGIQTMDHS LCAPETVSAA TQTVKNVCEQ GTSTVEQNSG KQDATVQTER
1210 1220 1230 1240 1250
GSGEKPASAP VDDTESLHSQ GEEEFEMPQP PHGHVLHRHT RTIREVRTLV
1260 1270 1280 1290 1300
TRVITDVYYV DGTEVERKVT EETEEPIVEC QECETEVSPS QTGGSSGDLG
1310 1320 1330 1340 1350
DISSFSSKAS SSHHTSSGTS LSAIHSSGSS GRGAGPLKGK TSGTEPADFA
1360 1370 1380 1390 1400
LPSSRGGPGK LSPRKGISQT GAPVCEEDGD AGLGIRQGGK APVTPRGRGR
1410 1420 1430 1440 1450
RGRPPSRTTG TRETVVSGPL GIEDTSPSMS PDDKSFTRIM PRVPDSTKRM
1460 1470 1480 1490 1500
DASSGALRRS DSPEIPFQAA TGSSDGLDSS SSGNSFVGLR VVAKWSSNGY
1510 1520 1530 1540 1550
FYSGKITRDV GAGKYKLLFD DGYECDVLGK DILLCDPIPL DTEVTALSED
1560 1570 1580 1590 1600
EYFSAGVVKG HRKESGELYY SIEKEGQRKW YKRMAVILSL EQGNRLREQY
1610 1620 1630 1640 1650
GLGPYEAVTP LTKAADISLD NLVEGKRKRR SNISSPATPT ASSSSSTTPT
1660 1670 1680 1690 1700
RKTTESPRAS MGVPSGKRKL TTSEEERSPA KRGRKSATVK PGTVGAAELV
1710 1720 1730 1740 1750
SPCESGDNTG EPSVLEEPRG PLPLNKTLFL GYAFLLTMAT TSDKLASRSK
1760 1770 1780 1790 1800
LLDGPTGSSE EEEEFLEIPP FNKQYTECQL RAGAGYILED FNEAQCNTAY
1810 1820 1830 1840 1850
QCLLIADQHC RTRKYFLCLA SGIPCVSHVW VHDSCHANQL QNYRNYLLPA
1860 1870 1880 1890 1900
GYSLEEQRIL DWQPRENPFQ NLKVLLVSDQ QQNFLELWSE ILMTGGAASV
1910 1920 1930 1940 1950
KQHHSSAHNK DIALGVFDVV VTDPSCPASV LKCAEALQLP VVSQEWVIQC
1960 1970
LIVGERIGFQ QHPKYKHDYV SH
Length:1,972
Mass (Da):212,859
Last modified:July 22, 2015 - v3
Checksum:i660B61314249A379
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116071 Genomic DNA. No translation available.
RefSeqiXP_006234927.1. XM_006234865.2.
XP_008760428.1. XM_008762206.1.

Genome annotation databases

EnsembliENSRNOT00000019025; ENSRNOP00000019025; ENSRNOG00000013837.
GeneIDi296099.
KEGGirno:296099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116071 Genomic DNA. No translation available.
RefSeqiXP_006234927.1. XM_006234865.2.
XP_008760428.1. XM_008762206.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019025.

PTM databases

iPTMnetiF1M842.
PhosphoSiteiF1M842.

Proteomic databases

PaxDbiF1M842.
PeptideAtlasiF1M842.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019025; ENSRNOP00000019025; ENSRNOG00000013837.
GeneIDi296099.
KEGGirno:296099.

Organism-specific databases

CTDi7158.
RGDi1308039. Tp53bp1.

Phylogenomic databases

eggNOGiKOG3548. Eukaryota.
ENOG411075K. LUCA.
GeneTreeiENSGT00390000011891.
InParanoidiF1M842.
OMAiCIDLTCD.
OrthoDBiEOG091G0BHF.
TreeFamiTF350227.

Enzyme and pathway databases

ReactomeiR-RNO-3232118. SUMOylation of transcription factors.
R-RNO-5693565. Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
R-RNO-5693571. Nonhomologous End-Joining (NHEJ).
R-RNO-5693607. Processing of DNA double-strand break ends.
R-RNO-69473. G2/M DNA damage checkpoint.

Gene expression databases

BgeeiENSRNOG00000013837.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR015125. 53-BP1_Tudor.
IPR001357. BRCT_dom.
IPR014722. Rib_L2_dom2.
[Graphical view]
PfamiPF09038. 53-BP1_Tudor. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF52113. SSF52113. 2 hits.
PROSITEiPS50172. BRCT. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF1M842_RAT
AccessioniPrimary (citable) accession number: F1M842
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 22, 2015
Last modified: September 7, 2016
This is version 41 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.