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  1. 1
    "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION.
    Category: Sequences.
    Strain: Brown Norway.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 22752 other entries.

  2. 2
    "Expression and localization of atypical PKC isoforms in liver parenchymal cells."
    Stross C., Keitel V., Winands E., Haussinger D., Kubitz R.
    Biol. Chem. 390:235-244(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10-596.
    Category: Sequences.
    Strain: Wistar.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Phosphorylation of tyrosine 256 facilitates nuclear import of atypical protein kinase C."
    White W.O., Seibenhener M.L., Wooten M.W.
    J. Cell. Biochem. 85:42-53(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, PHOSPHORYLATION AT TYR-265, MUTAGENESIS OF TYR-265.
    Category: Subcellular Location, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  4. 4
    "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-564, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 6826 other entries.

  5. 5
    "Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda /zeta but not on glycogen synthase kinase-3."
    Kim Y.B., Shulman G.I., Kahn B.B.
    J. Biol. Chem. 277:32915-32922(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: Fatty acid infusion impairs insulin stimulated PKC activationImported.
    Source: GeneRIF:84006.

    This publication is mapped to 2 other entries.

  6. 6
    "Atypical protein kinase C plays a critical role in protein transport from pre-Golgi intermediates."
    Tisdale E.J., Wang J., Silver R.B., Artalejo C.R.
    J. Biol. Chem. 278:38015-38021(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Atypical protein kinase C plays a critical role in protein transport from pre-Golgi intermediates.Imported.
    Source: GeneRIF:84006, RGD:620961.

    This publication is mapped to 2 other entries.

  7. 7
    "PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity."
    Matsumoto M., Ogawa W., Akimoto K., Inoue H., Miyake K., Furukawa K., Hayashi Y., Iguchi H., Matsuki Y., Hiramatsu R., Shimano H., Yamada N., Ohno S., Kasuga M., Noda T.
    J. Clin. Invest. 112:935-944(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:620961.

    This publication is mapped to 11 other entries.

  8. 8
    "Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation."
    Tisdale E.J.
    J. Biol. Chem. 278:52524-52530(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: protein kinase C iota/lambda binds to Rab 2 which inhibits aPKCiota/lambda-dependent GADPH phosphorylationImported.
    Source: GeneRIF:84006.

    This publication is cited by 1 and mapped to 10 other entries.

  9. 9
    "Protein kinase C modulation of the regulation of sarcoplasmic reticular function by protein kinase A-mediated phospholamban phosphorylation in diabetic rats."
    Watanuki S., Matsuda N., Sakuraya F., Jesmin S., Hattori Y.
    Br. J. Pharmacol. 141:347-359(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Source: RGD:620961.
  10. 10
    "Corticotropin-releasing hormone activates protein kinase C in an isoenzyme-specific manner."
    Dermitzaki E., Tsatsanis C., Charalampopoulos I., Androulidaki A., Alexaki V.I., Castanas E., Gravanis A., Margioris A.N.
    Biochem. Biophys. Res. Commun. 327:828-836(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:620961.
  11. 11
    "Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle."
    Herr H.J., Bernard J.R., Reeder D.W., Rivas D.A., Limon J.J., Yaspelkis B.B.
    J. Physiol. (Lond.) 565:627-636(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: in skeletal muscle insulin stimulates translocation of aPKC zeta and lambda but not Akt2 to the plasma membraneImported.
    Source: GeneRIF:84006.

    This publication is mapped to 2 other entries.

  12. 12
    "Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion."
    Nogueira T.C., Anhe G.F., Carvalho C.R., Curi R., Bordin S., Carpinelli A.R.
    Pancreas 37:309-315(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Report involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 2 other entries.

  13. 13
    "Skin immunosenescence: decreased receptor for activated C kinase-1 expression correlates with defective tumour necrosis factor-alpha production in epidermal cells."
    Corsini E., Racchi M., Lucchi L., Donetti E., Bedoni M., Viviani B., Galli C.L., Marinovich M.
    Br. J. Dermatol. 160:16-25(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:620961.

    This publication is mapped to 11 other entries.

  14. 14
    "Differential contributions of protein kinase C isoforms in the regulation of group IIA secreted phospholipase A2 expression in cytokine-stimulated rat fibroblasts."
    Sugita M., Kuwata H., Kudo I., Hara S.
    Biochim. Biophys. Acta 1801:70-76(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:620961.
  15. 15
    "Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses."
    Thaler J.P., Choi S.J., Sajan M.P., Ogimoto K., Nguyen H.T., Matsen M., Benoit S.C., Wisse B.E., Farese R.V., Schwartz M.W.
    Endocrinology 150:5362-5372(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: Results show that although hypothalamic aPKC signaling is not required for food intake inhibition by insulin or leptin it plays a key role in inflammatory anorexia and fever induced by LPS.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 2 other entries.

  16. 16
    "An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation."
    Rosse C., Formstecher E., Boeckeler K., Zhao Y., Kremerskothen J., White M.D., Camonis J.H., Parker P.J.
    PLoS Biol. 7:e1000235-e1000235(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location, Interaction.
    Annotation: Data show that the migration associated control of JNK by aPKCs determines JNK phosphorylation of the plasma membrane substrate paxillin.Imported.
    Source: GeneRIF:84006, RGD:620961.

    This publication is mapped to 11 other entries.

  17. 17
    "Knocking down the transcript of protein kinase C-lambda modulates hypothalamic glutathione peroxidase, melanocortin receptor and neuropeptide Y gene expression in amphetamine-treated rats."
    Hsieh Y.S., Yang S.F., Chen P.N., Chu S.C., Chen C.H., Kuo D.Y.
    J. Psychopharmacol. (Oxford) 25:982-994(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: Protein kinase C-lambda gene knockdown modulates hypothalamic glutathione peroxidase melanocortin receptor and neuropeptide Y gene expression in amphetamine-treated rats.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 5 other entries.

  18. 18
    "Spinal atypical protein kinase C activity is necessary to stabilize inactivity-induced phrenic motor facilitation."
    Strey K.A., Nichols N.L., Baertsch N.A., Broytman O., Baker-Herman T.L.
    J. Neurosci. 32:16510-16520(2012) [PubMed] [Europe PMC] [Abstract]
    Annotation: inactivity-induced increases in phrenic inspiratory output require local PKCzeta/iota activity to stabilize into a long-lasting phrenic motor facilitationImported.
    Source: GeneRIF:84006.

    This publication is mapped to 2 other entries.

  19. 19
    "FGF21 suppresses hepatic glucose production through the activation of atypical protein kinase Ciota/lambda."
    Kong L.J., Feng W., Wright M., Chen Y., Dallas-yang Q., Zhou Y.P., Berger J.P.
    Eur. J. Pharmacol. 702:302-308(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: FGF21 inhibits hepatic glucose production by the PI3K-dependent activation of protein kinase c iota.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 7 other entries.

  20. 20
    "PKClambda is critical in AMPA receptor phosphorylation and synaptic incorporation during LTP."
    Ren S.Q., Yan J.Z., Zhang X.Y., Bu Y.F., Pan W.W., Yao W., Tian T., Lu W.
    EMBO J. 32:1365-1380(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: PKClambda is critical in AMPA receptor phosphorylation and synaptic incorporation during long-term potentiation.Imported.
    Source: GeneRIF:84006, IntAct:F1M7Y5.

    This publication is mapped to 4 other entries.

  21. 21
    "Distinct Roles of PKCiota/lambda and PKMzeta in the Initiation and Maintenance of Hippocampal Long-Term Potentiation and Memory."
    Wang S., Sheng T., Ren S., Tian T., Lu W.
    Cell Rep 16:1954-1961(2016) [PubMed] [Europe PMC] [Abstract]
    Annotation: PKMzeta but not PKCiota knock-down disrupted previously established long-time memory. PKCiota and PKMz have distinct functions in long-term potentiation and memory with PKMzeta playing a specific role in memory maintenance.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 2 other entries.

  22. 22
    "Deletion of Protein Kinase C lambda in POMC Neurons Predisposes to Diet-Induced Obesity."
    Dorfman M.D., Krull J.E., Scarlett J.M., Guyenet S.J., Sajan M.P., Damian V., Nguyen H.T., Leitges M., Morton G.J., Farese R.V., Schwartz M.W., Thaler J.P.
    Diabetes 66:920-934(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: Acute inhibition of CNS aPKC activity increases food intake and glucose intolerance. Chronic inactivation of CNS aPKC activity increases body weight and food intake during high fat diet feeding.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 9 other entries.

  23. 23
    "Regulation of microtubule-associated motors drives intermediate filament network polarization."
    Leduc C., Etienne-Manneville S.
    J. Cell Biol. 216:1689-1703(2017) [PubMed] [Europe PMC] [Abstract]
    Annotation: Polarity signaling via CDC42/atypical protein kinase C can affect the dynamic turnover of the intermediate filament network to promote the polarization of the network itself.Imported.
    Source: GeneRIF:84006.

    This publication is mapped to 13 other entries.

  24. 24
    "An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3."
    Izumi Y., Hirose T., Tamai Y., Hirai S., Nagashima Y., Fujimoto T., Tabuse Y., Kemphues K.J., Ohno S.
    J. Cell Biol. 143:95-106(1998) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:620961.
  25. 25
    "Protein kinase C translocation and PKC-dependent protein phosphorylation during myocardial ischemia."
    Albert C.J., Ford D.A.
    Am. J. Physiol. 276:H642-50(1999) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:620961.

    This publication is mapped to 8 other entries.

1 to 25 of 25  Show

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