F1M778 (F1M778_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein LOC100912399 Ensembl ENSRNOP00000017968

Gene names

Name:

Map3k1 Ensembl ENSRNOP00000017968 RGD 620966

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000017968

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	1493 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSRNOP00000017968

Ontologies

Keywords
Domain	Zinc-finger RuleBase RU000353
Ligand	ATP-binding RuleBase RU000304 Metal-binding Nucleotide-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1M778 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 9AD531DA6CA0F246	FASTA	1,493	161,283
	10 20 30 40 50 60 MAAAAGDRAS SSGFPGAAAA SPEAGGGGGA LQGSGAPAAG AGLLRETGSA GRERADWRRQ 70 80 90 100 110 120 QLRKVRSVEL DQLPEQPLFL TASPPCPSTS PSPEPADAAA GASGFQPAAG PPPPGAASRC 130 140 150 160 170 180 GSHSAELAAA RDSGARSPAG AEPPSAAAPS GREMENKETL KGLHKMDDRP EERMIREKLK 190 200 210 220 230 240 ATCMPAWKHE WLERRNRRGP VVVKPIPIKG DGSEMSNLAA ELQGEGQAGS AAPAPKGRRS 250 260 270 280 290 300 PSPGSSPSGR SGKPESPGVR RKRVSPVPFQ SGRITPPRRA PSPDGFSPYS PEETSRRVNK 310 320 330 340 350 360 VMRARLYLLQ QIGPNSFLIG GDSPDNKYRV FIGPQNCSCG RGTFCIHLLF VMLRVFQLEP 370 380 390 400 410 420 SDPMLWRKTL KNFEVESLFQ KYHSRRSSRI KAPSRNTIQK FVSRMSNCHT LSSSSTSTSS 430 440 450 460 470 480 SENSIKDEEE QMCPICLLGM LDEESLTVCE DGCRNKLHHH CMSIWAEECR RNREPLICPL 490 500 510 520 530 540 CRSKWRSHDF YSHELSSPVD SPTSLRGVQQ PSSPQQPVAG SQRRNQESNF NLTHYGTQQI 550 560 570 580 590 600 PPAYKDLAEP WIQAFGMELV GCLFSRNWNV REMALRRLSH DVSGALLLAN GESTGTSGGG 610 620 630 640 650 660 SGGSLSAGAA SGSSQPSISG DVVEACCSVL SIVCADPVYK VYVAALKTLR AMLVYTPCHS 670 680 690 700 710 720 LAERIKLQRL LRPVVDTILV KCADANSRTS QLSISTLLEL CKGQAGELAV GREILKAGSI 730 740 750 760 770 780 GVGGVDYVLS CILGNQAESN NWQELLGRLC LIDRLLLEFP AEFYPHIVST DVSQAEPVEI 790 800 810 820 830 840 RYKKLLSLLA FALQSIDNSH SMVGKLSRRI YLSSARMVTT VPALFSKLVT MLSASGSSHF 850 860 870 880 890 900 ARMRRRLMAI ADEVEIAEVI QLGSEDTLDG QQDSSQALAP PRYPESSSLE HTAHVEKTGK 910 920 930 940 950 960 GLKATRLSAS SEDISDRLAG VSVGLPSSAT TEQPKPTVQT KGRPHSQCLN SSPLSPPQLM 970 980 990 1000 1010 1020 FPAISAPCSS APSVPAGSVT DASKHRPQAF VPCKIPSASP QTQRKFSLQF QRTCSENRDS 1030 1040 1050 1060 1070 1080 EKLSPVFTQS RPPPSSNIHR PKPSRPVPGS TSKLGDASKN SMTLDLNSAS QCDDSFGSGS 1090 1100 1110 1120 1130 1140 NSGGAVIPSE ETAFTPAEDK CRLDVNPELN SSIEDLLEAS MPSSDTTVTF KSEVAVLSPE 1150 1160 1170 1180 1190 1200 KAESDDTYKD DVNHNQKCKE KMEAEEEEAL AIAMAMSASQ DALPIVPQLQ VENGEDIIII 1210 1220 1230 1240 1250 1260 QQDTPETLPG HTKAKQPYRE DTEWLKGQQI GLGAFSSCYQ AQDVGTGTLM AVKQVTYVRN 1270 1280 1290 1300 1310 1320 TSSEQEEVVE ALREEIRMMS HLNHPNIIRM LGATCEKSNY NLFIEWMAGG SVAHLLSKYG 1330 1340 1350 1360 1370 1380 AFKESVVINY TEQLLRGLSY LHENQIIHRD VKGANLLIDS TGQRLRIADF GAAARLASKG 1390 1400 1410 1420 1430 1440 TGAGEFQGQL LGTIAFMAPE VLRGQQYGRS CDVWSVGCAI IEMACAKPPW NAEKHSNHLA 1450 1460 1470 1480 1490 LIFKIASATT APSIPSHLSP GLRDVALRCL ELQPQDRPPS RELLKHPVFR TTW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000017968.
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000017968.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06012815 Genomic DNA. No translation available.
IPI	IPI00210195.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000017968; ENSRNOP00000017968; ENSRNOG00000013177.
Organism-specific databases
RGD	6487511. LOC100912399. 620966. Map3k1.
Phylogenomic databases
GeneTree	ENSGT00700000104073.
OMA	SNFNLTH.
Gene expression databases
ArrayExpress	F1M778.
Family and domain databases
Gene3D	3.30.40.10. 1 hit.
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR007527. Znf_SWIM. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. PF04434. SWIM. 1 hit. [Graphical view]
SMART	SM00184. RING. 1 hit. SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. PS50089. ZF_RING_2. 1 hit. PS50966. ZF_SWIM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35582159.

Entry information

Entry name

F1M778_RAT

Accession

Primary (citable) accession number: F1M778

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	May 29, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)