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F1M656

- F1M656_RAT

UniProt

F1M656 - F1M656_RAT

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Protein

Tubby-like protein

Gene

Tulp3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. phosphatidylinositol binding Source: Ensembl

GO - Biological processi

  1. anterior/posterior pattern specification Source: Ensembl
  2. bone development Source: Ensembl
  3. brain development Source: Ensembl
  4. bronchus morphogenesis Source: Ensembl
  5. central nervous system neuron differentiation Source: Ensembl
  6. embryonic camera-type eye development Source: Ensembl
  7. embryonic digit morphogenesis Source: Ensembl
  8. embryonic neurocranium morphogenesis Source: Ensembl
  9. ganglion development Source: Ensembl
  10. negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
  11. negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning Source: Ensembl
  12. neural tube closure Source: Ensembl
  13. regulation of G-protein coupled receptor protein signaling pathway Source: Ensembl
  14. smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_269621. Hedgehog 'off' state.

Names & Taxonomyi

Protein namesi
Recommended name:
Tubby-like proteinUniRule annotation
Gene namesi
Name:Tulp3Imported
Synonyms:LOC100364088Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 4

Organism-specific databases

RGDi2321769. LOC100364088.
1585259. Tulp3.

Subcellular locationi

GO - Cellular componenti

  1. axoneme Source: Ensembl
  2. ciliary base Source: Ensembl
  3. intraciliary transport particle A Source: Ensembl
  4. nucleolus Source: Ensembl
  5. plasma membrane Source: Ensembl
  6. primary cilium Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiF1M656. baseline.

Family & Domainsi

Sequence similaritiesi

Belongs to the TUB family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00610000085970.
InParanoidiF1M656.
OMAiAFEDETM.
OrthoDBiEOG77HDDQ.
TreeFamiTF314076.

Family and domain databases

Gene3Di3.20.90.10. 1 hit.
InterProiIPR000007. Tubby_C.
IPR025659. Tubby_C-like.
IPR018066. Tubby_C_CS.
IPR005398. Tubby_N.
[Graphical view]
PfamiPF01167. Tub. 1 hit.
[Graphical view]
PRINTSiPR01573. SUPERTUBBY.
PR01574. TUBBYPROTEIN.
SUPFAMiSSF54518. SSF54518. 1 hit.
PROSITEiPS01200. TUB_1. 1 hit.
PS01201. TUB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1M656-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEAARCAPGS RGDSAFEDET LRLRQLKLDN QRALLEKKQR KKRLEPLMVQ
60 70 80 90 100
PNPEARLRRL KPRGSEEHTP LVDPQTPCSD VILHGIDGPA AFLKPEAQDL
110 120 130 140 150
ESKPQVLSVG SSPTPEEGTE GSADGESPVE TASKPDLQEI LQKHGILSSV
160 170 180 190 200
NYDEEPDEEA EDEGENLSSL PAQSEKESAG ASQKAASDTG ASGMTAQQGD
210 220 230 240 250
AQLGEVENLE DFAYSPAPRG VTVKCRVTRD KKGMDRGLFP TYYMHLEKEE
260 270 280 290 300
NRKVQVLGLK LHAWSRKSLY LDHTAPEILK KTADHHVGRF RSNLMGTKFT
310 320 330 340 350
VYDHGVNPVK AQGLVEKAHT RQELAAICYE TNVLGFKGPR KMSVIIPGMN
360 370 380 390 400
MNHERIPFRP RNEHESLLSK WQNKSMENLI ELHNKAPVWN DDTQSYVLNF
410 420 430 440 450
HGRVTQASVK NFQIVHGNDP DYIVMQFGRV ADDVFTLDYN YPLCALQAFA
460
IGLSSFDSKL ACE
Length:463
Mass (Da):51,596
Last modified:April 3, 2013 - v2
Checksum:iC9E2AA16F80B59F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06033601 Genomic DNA. No translation available.
AABR06033602 Genomic DNA. No translation available.
AABR06033603 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000007634; ENSRNOP00000007634; ENSRNOG00000005767.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06033601 Genomic DNA. No translation available.
AABR06033602 Genomic DNA. No translation available.
AABR06033603 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000007634 ; ENSRNOP00000007634 ; ENSRNOG00000005767 .

Organism-specific databases

RGDi 2321769. LOC100364088.
1585259. Tulp3.

Phylogenomic databases

GeneTreei ENSGT00610000085970.
InParanoidi F1M656.
OMAi AFEDETM.
OrthoDBi EOG77HDDQ.
TreeFami TF314076.

Enzyme and pathway databases

Reactomei REACT_269621. Hedgehog 'off' state.

Miscellaneous databases

NextBioi 35581799.
PROi F1M656.

Gene expression databases

ExpressionAtlasi F1M656. baseline.

Family and domain databases

Gene3Di 3.20.90.10. 1 hit.
InterProi IPR000007. Tubby_C.
IPR025659. Tubby_C-like.
IPR018066. Tubby_C_CS.
IPR005398. Tubby_N.
[Graphical view ]
Pfami PF01167. Tub. 1 hit.
[Graphical view ]
PRINTSi PR01573. SUPERTUBBY.
PR01574. TUBBYPROTEIN.
SUPFAMi SSF54518. SSF54518. 1 hit.
PROSITEi PS01200. TUB_1. 1 hit.
PS01201. TUB_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1M656_RAT
AccessioniPrimary (citable) accession number: F1M656
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: November 26, 2014
This is version 28 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3