Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein Ptprt

Gene

Ptprt

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphataseSAAS annotation, ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Protein PtprtImported
Submitted name:
Protein tyrosine phosphatase, receptor type, T (Predicted)Imported
Gene namesi
Name:PtprtImported
Synonyms:Ptprt_predictedImported
ORF Names:rCG_32138Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1309653. Ptprt.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei585 – 606HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

PTM databases

PhosphoSitePlusiF1LXJ9.

Expressioni

Gene expression databases

BgeeiENSRNOG00000032656.

Interactioni

Protein-protein interaction databases

IntActiF1LXJ9. 8 interactors.
STRINGi10116.ENSRNOP00000041324.

Structurei

3D structure databases

ProteinModelPortaliF1LXJ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 128MAMInterPro annotationAdd BLAST128
Domaini130 – 221Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST92
Domaini228 – 321Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini322 – 428Fibronectin type-IIIInterPro annotationAdd BLAST107
Domaini717 – 971Tyrosine-protein phosphataseInterPro annotationAdd BLAST255
Domaini891 – 962TYR_PHOSPHATASE_2InterPro annotationAdd BLAST72
Domaini1003 – 1265Tyrosine-protein phosphataseInterPro annotationAdd BLAST263
Domaini1179 – 1256TYR_PHOSPHATASE_2InterPro annotationAdd BLAST78

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4228. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00760000118900.
KOiK13297.
OMAiGPPITTR.
OrthoDBiEOG091G00CK.

Family and domain databases

CDDicd00063. FN3. 2 hits.
cd06263. MAM. 1 hit.
Gene3Di2.60.40.10. 3 hits.
3.90.190.10. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR000998. MAM_dom.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00041. fn3. 2 hits.
PF00629. MAM. 1 hit.
PF00102. Y_phosphatase. 2 hits.
[Graphical view]
PRINTSiPR00020. MAMDOMAIN.
PR00700. PRTYPHPHTASE.
SMARTiSM00060. FN3. 2 hits.
SM00137. MAM. 1 hit.
SM00194. PTPc. 2 hits.
SM00404. PTPc_motif. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF49265. SSF49265. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF52799. SSF52799. 2 hits.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 1 hit.
PS00740. MAM_1. 1 hit.
PS50060. MAM_2. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 2 hits.
PS50056. TYR_PHOSPHATASE_2. 2 hits.
PS50055. TYR_PHOSPHATASE_PTP. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1LXJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDPAVPTGS FMMVNSSGRA SGQKAHLLLP TLKENDTHCI DFHYYFSSRD
60 70 80 90 100
RSSPGALNVY VKVNGGPQGN PVWNVSGVVT EGWVKAELAI STFWPHFYQV
110 120 130 140 150
IFESVSLKGH PGYIAVDEVR VLAHPCRKAP HFLRLQNVEV NVGQNATFQC
160 170 180 190 200
IAGGKWSQHD KLWLQQWNGR DTALMVTRVV NHRRFSATVS VADTSQRSVS
210 220 230 240 250
KYRCVIRSDG GSGVSNYAEL IVKEPPTPIA PPELLAVGAT YLWIKPNANS
260 270 280 290 300
IIGDGPIILK EVEYRTTTGT WAETHIVDSP NYKLWHLDPD VEYEIRVLLT
310 320 330 340 350
RPGEGGTGPP GPPLTTRTKC AVPGAVPLES IQGGPFEEKI YIQWKPPNET
360 370 380 390 400
NGVITLYEIN YKAVGSLDPS ADLSSQRGKV FKLRNETHHL FVGLYPGTTY
410 420 430 440 450
SFTIKASTAK GFGPPVTTRI ATKISAPSMP EYDADSPLNE TDTTITVMLK
460 470 480 490 500
PAQSRGAPVS VYQLVVKEER LQKSRRAADI IECFSVPVSY RNASNLDSLH
510 520 530 540 550
YFAAELKPSN LPVTQPFTVG DNKTYNGYWN PPLSPLKSYS IYFQALSKAN
560 570 580 590 600
GETKINCVRL ATKGASTQNS NTVEPEKQVD NTVKMAGVIA GLLMFIIILL
610 620 630 640 650
GVMLTIKRRK LAKKQKETQS GAQREMGPVA STDKPTTKLS TNRNDEGFSS
660 670 680 690 700
SSQDVNGFTD GSRGELSQPT LTIQTHPYRT CDPVEMSYPR DQFQPAIRVA
710 720 730 740 750
DLLQHITQMK RGQGYGFKEE YEALPEGQTA SWDTAKEDEN RNKNRYGNII
760 770 780 790 800
SYDHSRVRLL VLDGDPHSDY INANYIDGYH RPRHYIATQG PMQETVKDFW
810 820 830 840 850
RMIWQENSAS IVMVTNLVEV GRVKCVRYWP DDTEVYGDIK VTLIETEPLA
860 870 880 890 900
EYVIRTFTVQ KKGYHEIREL RLFHFTSWPD HGVPCYATGL LGFVRQVKFL
910 920 930 940 950
NPPEAGPIVV HCSAGAGRTG CFIAIDTMLD MAENEGVVDI FNCVRELRAQ
960 970 980 990 1000
RVNLVQTEEQ YVFVHDAILE ACLCGNTAIP VCEFRSLYYN ISRLDPQTNS
1010 1020 1030 1040 1050
SQIKDEFQTL NIVTPRVRPE DCSIGLLPRN HDKNRSMDVL PLDRCLPFLI
1060 1070 1080 1090 1100
SVDGESSNYI NAALMDSHKQ PAAFVVTQHP LPNTVADFWR LVFDYNCSSV
1110 1120 1130 1140 1150
VMLNEMDTAQ LCMQYWPEKT SGCYGPIQVE FVSADIDEDI IHRIFRICNM
1160 1170 1180 1190 1200
ARPQDGYRIV QHLQYIGWPA YRDTPPSKRS LLKAVRRLEK WQEEYDGREG
1210 1220 1230 1240 1250
RTVVHCLNGG GRSGTFCAIC SVCEMIQQQN IIDVFHIVKT LRNNKSNMVE
1260
TLEQYKFVYE VALEYLSSF
Length:1,269
Mass (Da):142,502
Last modified:April 3, 2013 - v2
Checksum:i10BBC37791D23BFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054502 Genomic DNA. No translation available.
AABR07054503 Genomic DNA. No translation available.
AABR07054504 Genomic DNA. No translation available.
AABR07054505 Genomic DNA. No translation available.
AABR07054506 Genomic DNA. No translation available.
AABR07054507 Genomic DNA. No translation available.
CH474005 Genomic DNA. Translation: EDL96606.1.
RefSeqiNP_001102073.1. NM_001108603.1.
UniGeneiRn.198665.

Genome annotation databases

EnsembliENSRNOT00000044466; ENSRNOP00000041324; ENSRNOG00000032656.
GeneIDi362263.
KEGGirno:362263.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054502 Genomic DNA. No translation available.
AABR07054503 Genomic DNA. No translation available.
AABR07054504 Genomic DNA. No translation available.
AABR07054505 Genomic DNA. No translation available.
AABR07054506 Genomic DNA. No translation available.
AABR07054507 Genomic DNA. No translation available.
CH474005 Genomic DNA. Translation: EDL96606.1.
RefSeqiNP_001102073.1. NM_001108603.1.
UniGeneiRn.198665.

3D structure databases

ProteinModelPortaliF1LXJ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF1LXJ9. 8 interactors.
STRINGi10116.ENSRNOP00000041324.

PTM databases

PhosphoSitePlusiF1LXJ9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000044466; ENSRNOP00000041324; ENSRNOG00000032656.
GeneIDi362263.
KEGGirno:362263.

Organism-specific databases

CTDi11122.
RGDi1309653. Ptprt.

Phylogenomic databases

eggNOGiKOG4228. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00760000118900.
KOiK13297.
OMAiGPPITTR.
OrthoDBiEOG091G00CK.

Gene expression databases

BgeeiENSRNOG00000032656.

Family and domain databases

CDDicd00063. FN3. 2 hits.
cd06263. MAM. 1 hit.
Gene3Di2.60.40.10. 3 hits.
3.90.190.10. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR000998. MAM_dom.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF00041. fn3. 2 hits.
PF00629. MAM. 1 hit.
PF00102. Y_phosphatase. 2 hits.
[Graphical view]
PRINTSiPR00020. MAMDOMAIN.
PR00700. PRTYPHPHTASE.
SMARTiSM00060. FN3. 2 hits.
SM00137. MAM. 1 hit.
SM00194. PTPc. 2 hits.
SM00404. PTPc_motif. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF49265. SSF49265. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF52799. SSF52799. 2 hits.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 1 hit.
PS00740. MAM_1. 1 hit.
PS50060. MAM_2. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 2 hits.
PS50056. TYR_PHOSPHATASE_2. 2 hits.
PS50055. TYR_PHOSPHATASE_PTP. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF1LXJ9_RAT
AccessioniPrimary (citable) accession number: F1LXJ9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: November 30, 2016
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.