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Protein
Submitted name:

ALMS1, centrosome and basal body-associated protein

Gene

Alms1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
ALMS1, centrosome and basal body-associated proteinImported
Gene namesi
Name:Alms1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1311590. Alms1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1LVG9.

PTM databases

iPTMnetiF1LVG9.
PhosphoSitePlusiF1LVG9.

Expressioni

Gene expression databases

BgeeiENSRNOG00000022343.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050674.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3120 – 3241ALMS_motifInterPro annotationAdd BLAST122

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili10 – 44Sequence analysisAdd BLAST35
Coiled coili1641 – 1668Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IF7R. Eukaryota.
ENOG4111TD2. LUCA.
GeneTreeiENSGT00900000141032.
InParanoidiF1LVG9.
OMAiKPSIFYQ.
OrthoDBiEOG091G01OC.

Family and domain databases

InterProiView protein in InterPro
IPR028781. ALMS1.
IPR029299. ALMS_motif.
PANTHERiPTHR21553:SF22. PTHR21553:SF22. 7 hits.
PfamiView protein in Pfam
PF15309. ALMS_motif. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LVG9-1 [UniParc]FASTAAdd to basket

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        10         20         30         40         50
MEPEDLPWPD ELEEEEEEEE EEGKEEAENA SAAATEEART SEETGRLEEE
60 70 80 90 100
ELEGAGPEVD LDFNSESQLQ ESTDEEEDEL AKAWLQAHPD RPGQGFSLTP
110 120 130 140 150
PPTPPPSSRH QYRPVEHWGK REVIPLTYRA WQQTSYQDNA RAQFSNSSTL
160 170 180 190 200
LLEPEFQWDP EEVQRTESWH HLPQERDSFQ TLNISQTGID RVEGAEVKDL
210 220 230 240 250
PSQEGGESVQ AQCPVKEPKL DLLCSPLLVI QDDFAAPDLP LLTCMTQDQE
260 270 280 290 300
FEPDSLFQQS ELESFEVGGI PDKSEDIEWL ARPSEVSEAL IQATSESSSD
310 320 330 340 350
LVNSCFSISQ HPLTEGLQGK AKSDVLILFG DAKYASIYEN AGAHSERITE
360 370 380 390 400
LQREVDCSNL SITQAFPSSL PSFVPQEPTI ESEYHSSNLR MLRVSPDTLL
410 420 430 440 450
TTLTQTTGSV DQKIGAAAIS SPYSHGVQPG SFPQEELPDR HLTEEIRKVS
460 470 480 490 500
PAPRPAGQKP EMPTVPSSSY SKGIKSVFYR YPMSYSPQGK EPPNVSSVSG
510 520 530 540 550
SAENALPLTV TSVSQPQRET AKAFYQQTLS DSLLTAETLP VSVIPESGDQ
560 570 580 590 600
KTHLLSGFSL SYSHRGEDLP EDVVKVSTDS GSVDKKADIP TVSSSTYQHK
610 620 630 640 650
TKPGIIYYQE FPDSHVPIGT RKVVSQSGAA GQKTDLSAVP STSSSQAEKP
660 670 680 690 700
VPPSLLTLLG SHLPEDVFKA SYVCKSSEEP SGITALTSVS YSYKGRPNIS
710 720 730 740 750
HQEKFPDSYL IEEAQKILGS TVTVDQKTVT AKEKPSVFYQ QALPEGGLSA
760 770 780 790 800
EDLQVDQNIA IPMVTSASFS QREKPQVFYQ EALSGGHLPG EPPGPPDQNT
810 820 830 840 850
EAPTISPSSY FPGEESIIFY QAGFPGNTPS VVPFKVSRIS ELAEQKTNIT
860 870 880 890 900
TGPSGSYSVG EKSIIFYHQA LPDGHLSKEA SPAPADLKTG EPPVYSASCS
910 920 930 940 950
VEVKPIIFYQ QPLSDSPLTK GHNVSVVPGP TDQKTGIPAV PSTSQSYIER
960 970 980 990 1000
RSVSYQQEFP NVSEKALKVL GGVRSTEQKT EIPVVSSALL HTEVPTISSQ
1010 1020 1030 1040 1050
EDLPNLTEEA LQILGVAEEV PSVPSRDKTR LISYQKKLPD GTEVSLKSVG
1060 1070 1080 1090 1100
FGSTDQKTGA HIVSSSRREK SSGFHQQELP NTCGDALGTF HPEPVAQKVG
1110 1120 1130 1140 1150
KPTEPSNIQG KASALSPQQL PASHLTGEAL KVSDGSACVA QMPEAPAGPS
1160 1170 1180 1190 1200
IFYFHKERFS NYQKASPDCD LTENSLKSST VPGLSDQKKR PPVSSGSCSH
1210 1220 1230 1240 1250
KEKHKISAAD LLDAQAAELP TVIQRSCLHR EKLAISTVIK PDDPKIPLPT
1260 1270 1280 1290 1300
TCHASCAQKV KPVIFVQKQL SGRDQSEDIP KISTVSEPTV ANTGAPVLLS
1310 1320 1330 1340 1350
SSYPYREKSD FSSPKELPDR HPAKVDMQAS SSLGQADQIS RLPTVPPGTY
1360 1370 1380 1390 1400
SHSEKYQLIS EHVQELIDNL NSSESCLNAD IMMPSNSQID DGVIICKPES
1410 1420 1430 1440 1450
SRFANVGCEE IQDIDHGSKT LKEIQTLLME AENMALKRCN FSVPLVPFRD
1460 1470 1480 1490 1500
VSDVSFVQSK KVVCFKETPT SDVCIQKDSF AEEVPHTKYV QKDIGTQTNL
1510 1520 1530 1540 1550
KYQRNVRNWE FISSATFRSP LHEANGTARV AFDENFRQYR ATRSVMRSEP
1560 1570 1580 1590 1600
EDCSTGIGDK IIIPMMTIIK SDSSSDVSDG CCSWDNNLPE SLESVSDVFL
1610 1620 1630 1640 1650
NFFPYTSPKT SITDSREEEG LSESEDGYGS ADSLAAHVKY LLQCESSLNQ
1660 1670 1680 1690 1700
AKQILKNAEE EEYRVRAQAW NLKFNLGRDY GYPVSELNED DRRKVEEIKA
1710 1720 1730 1740 1750
KLFGHGRTTH VSEVLQSPRG IGCLPEAVCG HIIIESHEKG CYRTLTAEQP
1760 1770 1780 1790 1800
RPDSCHCVFR SVDPSDLIRG HRSPSSWRGR HINLSRSIDQ SNPHFKIGNS
1810 1820 1830 1840 1850
FQLQSHPPFE KLVPDDIKIS KGVGMPFHEH MDPQPSELIE PTCVPAKEMD
1860 1870 1880 1890 1900
FSSSSEILPS EPKKQFTTSI TFSSHQHSKC ISDSSGFKVD VTAGSQCTGP
1910 1920 1930 1940 1950
SLGVFKPHIP EEQISPRDLK QKISSPSSLQ RHSYTPVTIL VDSSRQRQKL
1960 1970 1980 1990 2000
PVDFEHSNQK GKLLQRSAFN FSHSEPSVST NVSFKGVQFS GNDTIVRQDK
2010 2020 2030 2040 2050
LISTVEVKEK NVTLTPDLPS CIFLEQGEES HTPHTDLHMR KCPSPSGLDI
2060 2070 2080 2090 2100
ASCIFLEQHK FFEQSQGQHV DDHEMREDYS LFPKCQGYIA ADPSDFPDQQ
2110 2120 2130 2140 2150
QCKPPGVDGH VRKQHYPLSP VQDCEVEEVQ CIPQSYFSNM VNVEAKVSDM
2160 2170 2180 2190 2200
VSPDAPDHFT AASTPPSSRK ALSCVRITLC PKTPSKLDSG TLDERFHSLD
2210 2220 2230 2240 2250
PASKTRINSE FNSDLRIISS RSLEPTSKLL TCKPVAQDQE SLVFLGPKSP
2260 2270 2280 2290 2300
LDLQVAESSL PDSKTISQDL KTTPPQNSQI VTSRQTQVNI SDLEEYSKPE
2310 2320 2330 2340 2350
GTPVPADGSQ EQNKAPFTTS SGMLSSDAVT QVTTESPEKM TFSSEIFINA
2360 2370 2380 2390 2400
DDRGQDIPYP TTQNPSRFAS SSSGQQITAS QGKDAQPVLL PYKPSGSSKM
2410 2420 2430 2440 2450
YYVPLLKPVP SYLDSKSDTT VESSHSGSND AIAPDFPPQV LGTRDDDLST
2460 2470 2480 2490 2500
TVNIKHKEGI YSKRAASKGK QPSQKGNAEA PVQMPVTWDK NVYKENQDEI
2510 2520 2530 2540 2550
ISRRVVIETA GPEEMPSQEK DLAGSSDITV QDRKTGNLPD AKSIKQKEGS
2560 2570 2580 2590 2600
LEIEPECHSE FANTTHSVFR SASFYFHHPV HLPQEQDLCR ESSGRNVLTQ
2610 2620 2630 2640 2650
HPWKDLFHCH SGHSGLPPPG PRSDNTEMEC TRVKSLSMDL NLGGHEKIHT
2660 2670 2680 2690 2700
IKNQARDTKE DKRPANDPKK DQKVTPELTS QCPMSLNELW NKYQERQKQQ
2710 2720 2730 2740 2750
KPSGACDNKE LSLVERLDRL AKLLQNPITH SLQASESTQD DRRWGRGARG
2760 2770 2780 2790 2800
WTGRRQHQQK GKQQRKWSKS LERGHSTGDF RKSKVLSPHE GGKSSQRNIE
2810 2820 2830 2840 2850
KIKLDKYILR KQPDFNNVSN TSLDSRPSEE SELLLTDSPN LFSSTESPVE
2860 2870 2880 2890 2900
SDVLTHTGRD MPLNERSSSI STVDTARLIQ AFGHDRLYLS PRQIKLYSSV
2910 2920 2930 2940 2950
TNQRRKHLEK PCKHKRKALN TACPQMTSEH TRRRHVQVAN RIMSSDSVSS
2960 2970 2980 2990 3000
AGSCLSLDST LSNEENVHML NKGVQAGNLE IVTGAKKYTQ DVGVTFPTPS
3010 3020 3030 3040 3050
SSEARLEEDS DMTSWSEEKA KEKKFLSNYL RGKNLRKNKP NPCEGVSWFV
3060 3070 3080 3090 3100
PVENRKSESK KENLPKIYRP AISWFEPVTQ TKPWREPLRE QNWQAQCMNS
3110 3120 3130 3140 3150
RGSLGGPGRD SGQSFLQPFV RATLQESLQL HRPDFISRSG ERIKRLKLLV
3160 3170 3180 3190 3200
QERKLQNLFQ NEREALFNTA RPLPRRVLLA VQKNKPIGKT EMIRRTRRFY
3210 3220 3230 3240
EQLPEVKKKR EEEKRKSEYT SYRLRAQHYK MKVTNHLLGR KVPWD
Length:3,245
Mass (Da):359,959
Last modified:April 3, 2013 - v2
Checksum:iA1847727189C293E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07061342 Genomic DNA. No translation available.
AABR07061343 Genomic DNA. No translation available.
AABR07073036 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000045735; ENSRNOP00000050674; ENSRNOG00000022343.
UCSCiRGD:1311590. rat.

Entry informationi

Entry nameiF1LVG9_RAT
AccessioniPrimary (citable) accession number: F1LVG9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: November 22, 2017
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported