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F1LSH3

- F1LSH3_RAT

UniProt

F1LSH3 - F1LSH3_RAT

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Protein
Submitted name: Origin recognition complex subunit 3
Gene
Orc3
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. DNA replication Source: InterPro
  2. neural precursor cell proliferation Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_204904. Activation of ATR in response to replication stress.
REACT_206997. CDT1 association with the CDC6:ORC:origin complex.
REACT_208829. Assembly of the pre-replicative complex.
REACT_209879. Activation of the pre-replicative complex.
REACT_211117. Orc1 removal from chromatin.
REACT_212543. Removal of licensing factors from origins.
REACT_213976. CDC6 association with the ORC:origin complex.
REACT_215168. Assembly of the ORC complex at the origin of replication.
REACT_223712. Association of licensing factors with the pre-replicative complex.

Names & Taxonomyi

Protein namesi
Submitted name:
Origin recognition complex subunit 3Imported
Gene namesi
Name:Orc3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 5

Organism-specific databases

RGDi1308457. Orc3.

Subcellular locationi

GO - Cellular componenti

  1. nuclear origin of replication recognition complex Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000011376.
OMAiCFVFKPN.
OrthoDBiEOG78PV8B.
TreeFamiTF101093.

Family and domain databases

InterProiIPR020795. ORC3.
[Graphical view]
PANTHERiPTHR12748. PTHR12748. 1 hit.
PfamiPF07034. ORC3_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1LSH3-1 [UniParc]FASTAAdd to Basket

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MATSSVSKGC FVFKPDFKKR KISVPIEDYF NNEELDSEDS KLRFETYRLL    50
WQRIKSETEQ LQEGLNENLF DNLVDFLQKS HSELQKNSGN WGSQMRLREI 100
PTAALILGVN VTDHDVIFRS LTETLHNNVT PYVVSLQAKD CPDVKHFLQK 150
LTSELIDCCV DRNSKEEKND KALRRTSYSM DSLSSWYSTV AQKTGPKMTS 200
KKRATCSQWQ SPPVVLILKN MESFSTKVLQ DFIIISSQHL HEFPLILIFG 250
IATSPVIIHR LLPHSVSSLL CIELFQSLSC KEHLTVVLDK LLLTPQFPFK 300
LSKKALQVLT NIFLYHDFSI QNFIKGLKLS LLEHFYSQPL SVLCCDLSEA 350
KKRINVFSVN QCEKIRRLPS FRRYVENQPL EKQVALLTNE TFLKEETQSL 400
LEDLHVYHIN YFLVLRCLHN FTSSLPKYPL GRQIRELYCT CLEKKIWDSE 450
EYESALQLLR MLAKDELMGI LEQCVKVLNS STEKQLSNTA QKIKGFLTQF 500
QNLDDSKEEE DACGSQPKGL QKTDLYHLQK SLLEMKELRR TTKKPTKFEM 550
LRENVINFID NLVRDYLLPP EGQPLHEVVY FSAANTLREH LNAAPRIALH 600
TALNNPYYYL KNEALKSEEG CIPSVAPDIC IAYKLHLECS RLINLVDWSE 650
AFATVVTAAE KMDTNSTVSE EMSEIIHARF IRAVSELELL GFIKPTKQKT 700
DHVARLTWGG C 711
Length:711
Mass (Da):81,867
Last modified:April 3, 2013 - v2
Checksum:i25DB9E205C0333A7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06036451 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000011085; ENSRNOP00000011085; ENSRNOG00000008314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06036451 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000011085 ; ENSRNOP00000011085 ; ENSRNOG00000008314 .

Organism-specific databases

RGDi 1308457. Orc3.

Phylogenomic databases

GeneTreei ENSGT00390000011376.
OMAi CFVFKPN.
OrthoDBi EOG78PV8B.
TreeFami TF101093.

Enzyme and pathway databases

Reactomei REACT_204904. Activation of ATR in response to replication stress.
REACT_206997. CDT1 association with the CDC6:ORC:origin complex.
REACT_208829. Assembly of the pre-replicative complex.
REACT_209879. Activation of the pre-replicative complex.
REACT_211117. Orc1 removal from chromatin.
REACT_212543. Removal of licensing factors from origins.
REACT_213976. CDC6 association with the ORC:origin complex.
REACT_215168. Assembly of the ORC complex at the origin of replication.
REACT_223712. Association of licensing factors with the pre-replicative complex.

Miscellaneous databases

NextBioi 35577080.
PROi F1LSH3.

Family and domain databases

InterProi IPR020795. ORC3.
[Graphical view ]
PANTHERi PTHR12748. PTHR12748. 1 hit.
Pfami PF07034. ORC3_N. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1LSH3_RAT
AccessioniPrimary (citable) accession number: F1LSH3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: September 3, 2014
This is version 22 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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