Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Glutathione reductase

Gene

Gsr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-3299685. Detoxification of Reactive Oxygen Species.
R-RNO-499943. Interconversion of nucleotide di- and triphosphates.
R-RNO-5628897. TP53 Regulates Metabolic Genes.

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione reductaseImported
Gene namesi
Name:GsrImported
ORF Names:rCG_43149Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi621747. Gsr.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSRNOG00000014915.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 278FAD/NAD-binding_domInterPro annotationAdd BLAST250
Domaini299 – 409Pyr_redox_dimInterPro annotationAdd BLAST111

Phylogenomic databases

eggNOGiKOG0405. Eukaryota.
COG1249. LUCA.
GeneTreeiENSGT00390000007578.
KOiK00383.
TreeFamiTF105353.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 1 hit.
InterProiView protein in InterPro
IPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
IPR006322. Glutathione_Rdtase_euk/bac.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
PANTHERiPTHR42737. PTHR42737. 1 hit.
PfamiView protein in Pfam
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01421. gluta_reduc_1. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LRE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWNTAVHSEF IHDHVDYGFQ NCKSKFNWHV IKEKRDAYVS RLNNIYQNNL
60 70 80 90 100
TKSHIEVIHG YATFADGPQP TVEVNGKKFT APHILIATGG VPTVPHENQI
110 120 130 140 150
PGASLGITSD GFFQLEDLPS RSVIVGAGYI AVEIAGILSA LGSKTSLMIR
160 170 180 190 200
HDKVLRSFDS LISSNCTEEL ENAGVEVLKF SQVKEVKKTP SGLELHVVTA
210 220 230 240 250
LPGRKPTVTT IPDVDCLLWA IGRDPNSKGL NLNKLGIQTD DKGHILVDEF
260 270 280 290 300
QNTNVKGVYA VGDVCGKALL TPVAIAAGRK LAHRLFEGKE DSRLDYDNIP
310 320 330 340 350
TVVFSHPPIG TVGLTEDEAV HKYGKDNVKI YSTAFTPMYH AVTTRKTKCV
360 370 380 390 400
MKMVCANKEE KVVGIHMQGI GCDEMLQGFA VAVKMGATKA DFDNTVAIHP
410
TSSEELVTLR
Length:410
Mass (Da):44,789
Last modified:April 3, 2013 - v2
Checksum:iD433AAEDEB6D9BA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07026063 Genomic DNA. No translation available.
CH473970 Genomic DNA. Translation: EDM09143.1.
RefSeqiNP_446358.2. NM_053906.2.
UniGeneiRn.19721.

Genome annotation databases

EnsembliENSRNOT00000020252; ENSRNOP00000020252; ENSRNOG00000014915.
GeneIDi116686.
KEGGirno:116686.

Similar proteinsi

Entry informationi

Entry nameiF1LRE1_RAT
AccessioniPrimary (citable) accession number: F1LRE1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: August 30, 2017
This is version 55 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported