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Protein
Submitted name:

Glutathione reductase

Gene

Gsr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-3299685 Detoxification of Reactive Oxygen Species
R-RNO-499943 Interconversion of nucleotide di- and triphosphates
R-RNO-5628897 TP53 Regulates Metabolic Genes

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione reductaseImported
Gene namesi
Name:GsrImported
ORF Names:rCG_43149Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi621747 Gsr

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiF1LRE1
PRIDEiF1LRE1

Expressioni

Gene expression databases

BgeeiENSRNOG00000014915
ExpressionAtlasiF1LRE1 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 278FAD/NAD-binding_domInterPro annotationAdd BLAST250
Domaini299 – 409Pyr_redox_dimInterPro annotationAdd BLAST111

Phylogenomic databases

eggNOGiKOG0405 Eukaryota
COG1249 LUCA
GeneTreeiENSGT00390000007578
KOiK00383
TreeFamiTF105353

Family and domain databases

Gene3Di3.30.390.30, 1 hit
3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR016156 FAD/NAD-linked_Rdtase_dimer_sf
IPR006322 Glutathione_Rdtase_euk/bac
IPR004099 Pyr_nucl-diS_OxRdtase_dimer
PANTHERiPTHR42737 PTHR42737, 1 hit
PfamiView protein in Pfam
PF07992 Pyr_redox_2, 1 hit
PF02852 Pyr_redox_dim, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
SSF55424 SSF55424, 1 hit
TIGRFAMsiTIGR01421 gluta_reduc_1, 1 hit

Sequencei

Sequence statusi: Complete.

F1LRE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWNTAVHSEF IHDHVDYGFQ NCKSKFNWHV IKEKRDAYVS RLNNIYQNNL
60 70 80 90 100
TKSHIEVIHG YATFADGPQP TVEVNGKKFT APHILIATGG VPTVPHENQI
110 120 130 140 150
PGASLGITSD GFFQLEDLPS RSVIVGAGYI AVEIAGILSA LGSKTSLMIR
160 170 180 190 200
HDKVLRSFDS LISSNCTEEL ENAGVEVLKF SQVKEVKKTP SGLELHVVTA
210 220 230 240 250
LPGRKPTVTT IPDVDCLLWA IGRDPNSKGL NLNKLGIQTD DKGHILVDEF
260 270 280 290 300
QNTNVKGVYA VGDVCGKALL TPVAIAAGRK LAHRLFEGKE DSRLDYDNIP
310 320 330 340 350
TVVFSHPPIG TVGLTEDEAV HKYGKDNVKI YSTAFTPMYH AVTTRKTKCV
360 370 380 390 400
MKMVCANKEE KVVGIHMQGI GCDEMLQGFA VAVKMGATKA DFDNTVAIHP
410
TSSEELVTLR
Length:410
Mass (Da):44,789
Last modified:April 3, 2013 - v2
Checksum:iD433AAEDEB6D9BA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07026063 Genomic DNA No translation available.
CH473970 Genomic DNA Translation: EDM09143.1
RefSeqiNP_446358.2, NM_053906.2
UniGeneiRn.19721

Genome annotation databases

EnsembliENSRNOT00000020252; ENSRNOP00000020252; ENSRNOG00000014915
GeneIDi116686
KEGGirno:116686

Similar proteinsi

Entry informationi

Entry nameiF1LRE1_RAT
AccessioniPrimary (citable) accession number: F1LRE1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: May 23, 2018
This is version 62 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health