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F1LQZ8

- F1LQZ8_RAT

UniProt

F1LQZ8 - F1LQZ8_RAT

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Protein
Submitted name:

Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial

Gene

Dhtkd1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. hematopoietic progenitor cell differentiation Source: Ensembl
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrialImported
Gene namesi
Name:Dhtkd1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 17

Organism-specific databases

RGDi1308092. Dhtkd1.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliF1LQZ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063092.
OMAiLCSGKHY.
OrthoDBiEOG7CZK4Z.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 2 hits.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SUPFAMiSSF52518. SSF52518. 3 hits.

Sequencei

Sequence statusi: Complete.

F1LQZ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASATVAAAG RALRRAVPLL RRSYQTERGV YGYRPRKAGS GEPRGDRARP
60 70 80 90 100
SVDHGLARLV TVYCEHGHKA AQINPLFPGQ ALLDTVPEIQ ALVQTLQGPF
110 120 130 140 150
TTTGLLNMGK EEASLEEVLA YLNHIYCGPI SIETAQLQSQ EEKDWFARRF
160 170 180 190 200
EELKKETFTT EERKHLSKLL LESQEFDHFL ATKFATVKRY GGEGAESMMG
210 220 230 240 250
FFHELLKLSA YGGITDIIIG MPHRGRLNLL TGLLQLPPEL MFRKMRGLSE
260 270 280 290 300
FPENVAAIGD VLSHLTSSVD LDFGAHRPLH VTMLPNPSHL EAINPVAVGK
310 320 330 340 350
TRGRQQSQED GDYSPNGSAQ PGDKVICLQV HGDASFCGQG IVLETFTLSN
360 370 380 390 400
LPHFRIGGSI HLIVNNQLGY TTPAERGRSS LYSSDIGKLV GCAIIHVNGD
410 420 430 440 450
SPEEVVRATR LAFEYQRQFR KDVIIDLLCY RQWGHNELDE PFFTNPVMYK
460 470 480 490 500
IIRARKSIPD TYAEHLIASG LMTQEEVSDI KASYYAKLNG HLANVAHYSP
510 520 530 540 550
PAPHLQARWQ GLVQPAACVT TWDTGVPLEL LRFVGVKSVE VPEELQLHSH
560 570 580 590 600
LLKMYVQQSR MEKVKNGTNL DWATAETLAL GSLLAQGFNV RLSGQDVGRG
610 620 630 640 650
TFSQRHAMVV CQNTDDVYIP LNHMDPNQKG FLESCVSNNY LSEQLMIFME
660 670 680 690 700
TDYSFKVNLV VHRLLSNCRF WFENITCVFV TLLXEGHGRA GLLFCSHFFF
710 720 730 740 750
NMNHAFDFSF PVLSCCTIER NIFTKMCDSA EEGVDSDTVN MFVVHPTTPA
760 770 780 790 800
QYFHLLRRQM MRNFRKPLIA SPKMLLRYPV AVSTLEEMAP GTAFKPVIGD
810 820 830 840 850
SSVDPKNVKT LIFCSGKHFY ALLKQRESLG AKKRDFAIIR LEELCPFPLD
860 870 880 890 900
SLQQEMGKYK HVQDIIWSQE EPQNMGPWSF VYPRFEKQLA CKLRLVSRPP
910 920
LPAPAVGIGT VHQQQHEAIL FKTFTS
Length:926
Mass (Da):104,029
Last modified:April 3, 2013 - v2
Checksum:i1D3E29A3E59FD9F0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06092986 Genomic DNA. No translation available.
AABR06092987 Genomic DNA. No translation available.
AABR06092988 Genomic DNA. No translation available.
AABR06092989 Genomic DNA. No translation available.
AABR06092990 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000065978; ENSRNOP00000059952; ENSRNOG00000023587.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06092986 Genomic DNA. No translation available.
AABR06092987 Genomic DNA. No translation available.
AABR06092988 Genomic DNA. No translation available.
AABR06092989 Genomic DNA. No translation available.
AABR06092990 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F1LQZ8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000065978 ; ENSRNOP00000059952 ; ENSRNOG00000023587 .

Organism-specific databases

RGDi 1308092. Dhtkd1.

Phylogenomic databases

GeneTreei ENSGT00530000063092.
OMAi LCSGKHY.
OrthoDBi EOG7CZK4Z.

Miscellaneous databases

NextBioi 35576604.

Family and domain databases

Gene3Di 3.40.50.970. 1 hit.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 2 hits.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SUPFAMi SSF52518. SSF52518. 3 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1LQZ8_RAT
AccessioniPrimary (citable) accession number: F1LQZ8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: October 29, 2014
This is version 22 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3