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F1LQW5

- F1LQW5_RAT

UniProt

F1LQW5 - F1LQW5_RAT

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Protein
Submitted name:

Prominin-2

Gene

Prom2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. negative regulation of caveolin-mediated endocytosis Source: Ensembl
  2. negative regulation of pinocytosis Source: Ensembl
  3. positive regulation of cell projection organization Source: Ensembl
  4. positive regulation of protein phosphorylation Source: Ensembl
  5. regulation of Cdc42 GTPase activity Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Prominin-2Imported
Gene namesi
Name:Prom2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 3

Organism-specific databases

RGDi621435. Prom2.

Subcellular locationi

GO - Cellular componenti

  1. cell projection Source: Ensembl
  2. cell surface Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
  4. integral component of membrane Source: InterPro
  5. plasma membrane Source: Ensembl
  6. prominosome Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063586.
OMAiRYETYRW.
OrthoDBiEOG7TQV02.
TreeFamiTF324631.

Family and domain databases

InterProiIPR008795. Prominin.
[Graphical view]
PANTHERiPTHR22730. PTHR22730. 1 hit.
PfamiPF05478. Prominin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1LQW5 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRTLDLMVP LLGLSLGLAL SLPRAVAADC GSLGRVEHLA FAPVPGTEPT
60 70 80 90 100
APRVRAPWPL DSLYGTVRRF LSVVQLNPFP AELIKTLLND PSSVKTDEVV
110 120 130 140 150
RYEAGYVVCA VIAGLYLLLV PITGLCFCCC RCRRRCGGRV KTEHKAMACE
160 170 180 190 200
RGTLMTFLLL TTLMLLIGMV CAFATNQFTH SQTGPSVEAV PETLLSLRGL
210 220 230 240 250
VSDVPKKLQA VADQFSLPQK QVSKDLDGVG ENLGNIIHNQ LKSTVYPVLA
260 270 280 290 300
SVHGLGQALQ VSIDHLQSVN ATSVELREGQ QHLGPPVQAH RERLLALLQE
310 320 330 340 350
SWCHENCKGA LSQASALQLG ADFSQMPPVD DVLHRLQGVP EANFSSMVQE
360 370 380 390 400
ENATFNNLPI LVHMQMVSVV KDLKKALAEQ PEGVRMLAQA FPGSEATSRW
410 420 430 440 450
SQALEGLEQR SRPYLQDVQR YETYRWILGC VLCSAILLVV ICNLLGLSLG
460 470 480 490 500
IWGLFAREDP SHSETKGEAG ARFLMAGVAF SFLFAAPLIL LVFATFLVGG
510 520 530 540 550
NVQTLVCRSW ESGELYEFVD TPGNLPPSMN LSYLLGLRKN ISVFQAYRQC
560 570 580 590 600
KAGTALWKVL QLNDSYDLDK HLDIKQYTHK LQQELQSFKV DLKDLDLLNP
610 620 630 640 650
AARQNLEALQ SSGLEKIHYR DFLVQIQKPV VKTDMGQLAK ELEGLAQAHN
660 670 680 690 700
ESLRRQQLQE EARELRSLYQ EKVVPQENLV AKLNPSIRVL ESSAPKLQVN
710 720 730 740 750
TSDLLDIVAR LKGELPAQLN HILRNATECF LTREMGYFSQ YVTWVREEVT
760 770 780 790 800
QHIATCQPFS KALDDGHMIL CDMGQPLECL LVLPGLVHLL PHPQHHLRGQ
810 820 830 840 850
DLQVLPSHPE TAQLHQLRRD TALPYPQGHL PEAIEPTGQG DTWGFPVLLP
860 870 880
CLSLDQTTSV TSVPEPRLAS SAGLSPVPHL YSFCS
Length:885
Mass (Da):97,817
Last modified:April 3, 2013 - v2
Checksum:iA094B147FF2D747A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06026107 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000020354; ENSRNOP00000020354; ENSRNOG00000014710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06026107 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000020354 ; ENSRNOP00000020354 ; ENSRNOG00000014710 .

Organism-specific databases

RGDi 621435. Prom2.

Phylogenomic databases

GeneTreei ENSGT00530000063586.
OMAi RYETYRW.
OrthoDBi EOG7TQV02.
TreeFami TF324631.

Miscellaneous databases

NextBioi 35576574.
PROi F1LQW5.

Family and domain databases

InterProi IPR008795. Prominin.
[Graphical view ]
PANTHERi PTHR22730. PTHR22730. 1 hit.
Pfami PF05478. Prominin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1LQW5_RAT
AccessioniPrimary (citable) accession number: F1LQW5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: October 29, 2014
This is version 24 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3