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Protein
Submitted name:

Cholecystokinin receptor type A

Gene

Cckar

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-RNO-375276. Peptide ligand-binding receptors.
R-RNO-416476. G alpha (q) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Cholecystokinin receptor type AImported
Gene namesi
Name:CckarImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi2289. Cckar.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei60 – 8122HelicalSequence analysisAdd
BLAST
Transmembranei93 – 11422HelicalSequence analysisAdd
BLAST
Transmembranei134 – 15219HelicalSequence analysisAdd
BLAST
Transmembranei173 – 19422HelicalSequence analysisAdd
BLAST
Transmembranei224 – 24724HelicalSequence analysisAdd
BLAST
Transmembranei327 – 34822HelicalSequence analysisAdd
BLAST
Transmembranei368 – 38821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1LQR7.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063137.

Structurei

3D structure databases

ProteinModelPortaliF1LQR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini73 – 386314G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118781.
OMAiYSYSHMS.
OrthoDBiEOG091G084J.
TreeFamiTF315303.

Family and domain databases

Gene3Di4.10.670.10. 1 hit.
InterProiIPR009126. Cholcskin_rcpt.
IPR000596. Cholcy_rcpt_A.
IPR015276. CholecystokininA_recpt_N.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
PF09193. CholecysA-Rec_N. 1 hit.
[Graphical view]
PRINTSiPR01822. CCYSTOKININR.
PR00524. CCYSTOKNINAR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1LQR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHSPARQHL VESSRMDVVD SLLMNGSNIT PPCELGLENE TLFCLDQPQP
60 70 80 90 100
SKEWQSALQI LLYSIIFLLS VLGNTLVITV LIRNKRMRTV TNIFLLSLAV
110 120 130 140 150
SDLMLCLFCM PFNLIPNLLK DFIFGSAVCK TTTYFMGTSV SVSTFNLVAI
160 170 180 190 200
SLERYGAICR PLQSRVWQTK SHALKVIAAT WCLSFTIMTP YPIYSNLVPF
210 220 230 240 250
TKNNNQTANM CRFLLPSDAM QQSWQTFLLL ILFLLPGIVM VVAYGLISLE
260 270 280 290 300
LYQGIKFDAS QKKSAKEKKP STGSSTRYED SDGCYLQKSR PPRKLELQQL
310 320 330 340 350
SSGSGGSRLN RIRSSSSAAN LIAKKRVIRM LIVIVVLFFL CWMPIFSANA
360 370 380 390 400
WRAYDTVSAE KHLSGTPISF ILLLSYTSSC VNPIIYCFMN KRFRLGFMAT
410 420 430 440
FPCCPNPGPP GVRGEVGEEE DGRTIRASLS RYSYSHMSTS APPP
Length:444
Mass (Da):49,631
Last modified:April 3, 2013 - v2
Checksum:iA2596E7505C2FB11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07015493 Genomic DNA. No translation available.
RefSeqiXP_008768410.1. XM_008770188.1.
UniGeneiRn.10184.

Genome annotation databases

EnsembliENSRNOT00000065366; ENSRNOP00000063137; ENSRNOG00000043124.
GeneIDi24889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07015493 Genomic DNA. No translation available.
RefSeqiXP_008768410.1. XM_008770188.1.
UniGeneiRn.10184.

3D structure databases

ProteinModelPortaliF1LQR7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063137.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiF1LQR7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000065366; ENSRNOP00000063137; ENSRNOG00000043124.
GeneIDi24889.

Organism-specific databases

CTDi886.
RGDi2289. Cckar.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118781.
OMAiYSYSHMS.
OrthoDBiEOG091G084J.
TreeFamiTF315303.

Enzyme and pathway databases

ReactomeiR-RNO-375276. Peptide ligand-binding receptors.
R-RNO-416476. G alpha (q) signalling events.

Family and domain databases

Gene3Di4.10.670.10. 1 hit.
InterProiIPR009126. Cholcskin_rcpt.
IPR000596. Cholcy_rcpt_A.
IPR015276. CholecystokininA_recpt_N.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
PF09193. CholecysA-Rec_N. 1 hit.
[Graphical view]
PRINTSiPR01822. CCYSTOKININR.
PR00524. CCYSTOKNINAR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF1LQR7_RAT
AccessioniPrimary (citable) accession number: F1LQR7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: September 7, 2016
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.