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F1LQI4

- F1LQI4_RAT

UniProt

F1LQI4 - F1LQI4_RAT

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Protein
Submitted name:

Aggrecan core protein

Gene

Acan

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. hyaluronic acid binding Source: InterPro

GO - Biological processi

  1. cell adhesion Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Aggrecan core proteinImported
Gene namesi
Name:AcanImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 1

Organism-specific databases

RGDi68358. Acan.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

ExpressionAtlasiF1LQI4. baseline.

Family & Domainsi

Sequence similaritiesi

Contains C-type lectin domain.SAAS annotation

Keywords - Domaini

Immunoglobulin domainSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119025.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.100.10. 5 hits.
InterProiIPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
IPR000538. Link.
IPR000436. Sushi_SCR_CCP.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
PF00084. Sushi. 1 hit.
PF07686. V-set. 1 hit.
PF00193. Xlink. 4 hits.
[Graphical view]
PRINTSiPR01265. LINKMODULE.
SMARTiSM00032. CCP. 1 hit.
SM00034. CLECT. 1 hit.
SM00406. IGv. 1 hit.
SM00445. LINK. 4 hits.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 5 hits.
SSF57535. SSF57535. 1 hit.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
PS01241. LINK_1. 3 hits.
PS50963. LINK_2. 4 hits.
PS50923. SUSHI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1LQI4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTLLLVFVT LRVIAAVISE EVPDHDNSLS VSIPQPSPLK ALLGTSLTIP
60 70 80 90 100
CYFIDPMHPV TTAPSTAPLT PRIKWSRVSK EKEVVLLVAT EGQVRVNSIY
110 120 130 140 150
QDKVSLPNYP AIPSDATLEI QNLRSNDSGI YRCEVMHGIE DSEATLEVIV
160 170 180 190 200
KGIVFHYRAI STRYTLDFDR AQRACLQNSA IIATPEQLQA AYEDGFHQCD
210 220 230 240 250
AGWLADQTVR YPIHTPREGC YGDKDEFPGV RTYGIRDTNE TYDVYCFAEE
260 270 280 290 300
MEGEVFYATS PEKFTFQEAA NECRRLGARL ATTGQLYLAW QGGMDMCSAG
310 320 330 340 350
WLADRSVRYP ISKARPNCGG NLLGVRTVYL HANQTGYPDP SSRYDAICYT
360 370 380 390 400
GEDFVDIPEN FFGVGGEEDI TIQTVTWPDL ELPLPRNITE GEARGNVILT
410 420 430 440 450
AKPIFDMSPT VSEPGEALTL APEVGTTVFP EAGERTEKTT RPWGFPEEAT
460 470 480 490 500
RGPDSATAFA SEDLVVRVTI SPGAVEVPGQ PRLPGGVVFH YRPGSTRYSL
510 520 530 540 550
TFEEAQQACI RTGAAIASPE QLQAAGYEQC DAGWLXXXTV XYPIVSPRTP
560 570 580 590 600
CVGDKDSSPG VRTYGVRPSS ETYDVYCYVD KLEGEVFFAT QMEQFTFQEA
610 620 630 640 650
QAFCAAQNAT LASTGQLYAA WSQGLDKCYA GWLADGTLRY PIVNPRPACG
660 670 680 690 700
GDKPGVRTVY LYPNQTGLPD PLSKHHAFCF RGVSVAPSPG GTPTSPSDIE
710 720 730 740 750
DWIVTRVEPG VDAVPLEPET TEVPYFTTEP EKQTEWEPAY TPVGTSPLPG
760 770 780 790 800
IPPTWLPTVP AAEEHTESPS ASQEPSASQV PSTSEEPYTP SLAVPSGTEL
810 820 830 840 850
PSSGDTSGAP DLSGDFTGST DTSGRLDSSG EPSGGSESGL PSGDLDSSGL
860 870 880 890 900
GPTVSSGLPV ESGSASGDGE IPWSSTPTVG RLPSGGESLE GSASASGTGD
910 920 930 940 950
LSGLPSGGEI TETSASGTEE ISGLPSGGDD LETSTSGIDG ASVLPTGRGG
960 970 980 990 1000
LETSASGVED LSGLPSGEEG SETSTSGIED ISVLPTGESP ETSASGVGDL
1010 1020 1030 1040 1050
SGLPSGGESL ETSASGVEDV TQLPTERGGL ETSASGIEDI TVLPTGRENL
1060 1070 1080 1090 1100
ETSASGVEDV SGLPSGKEGL ETSASGIEDI SVFPTEAEGL ETSASGGYVS
1110 1120 1130 1140 1150
GIPSGEDGTE TSTSGVEGVS GLPSGGEGLE TSASGVEDLG LPTRDSLETS
1160 1170 1180 1190 1200
ASGVDVTGYP SGREDTETSV PGVGDDLSGL PSGQEGLETS ASGAEDLGGL
1210 1220 1230 1240 1250
PSGKEDLVGS ASGALDFGKL PSGTLGSGQT PEASGLPSGF SGEYSGVDIG
1260 1270 1280 1290 1300
SGPSSGLPDF SGLPSGFPTV SLVDSTLVEV ITATTASELE GRGTISVSGS
1310 1320 1330 1340 1350
GEESGPPLSE LDSSADISGL PSGTELSGQT SGSLDVSGET SGFFDVSGQP
1360 1370 1380 1390 1400
FGSSGTGEGT SGIPEVSGQP SGSPDTTEIS ELSGLSSGQP DVSGEGSGIL
1410 1420 1430 1440 1450
FGSGQSSGIT SVSGETSGIS DLSGQPSGFP VLSGTTPGTP DLASGAMSGS
1460 1470 1480 1490 1500
GDSSGITFVD TSLIEVTPTT FREEEGLGSV ELSGLPSGET DLSGTSGMVD
1510 1520 1530 1540 1550
VSGQSSGAID SSGLISPTPE FSGLPSGVAE VSGEVSGVET GSSLSSGAFD
1560 1570 1580 1590 1600
GSGLVSGFPT VSLVDRTLVE SITLAPTAQE AGEGPSSILE FSGAHSGTPD
1610 1620 1630 1640 1650
ISGDLSGSLD QSTWQPGWTE ASTEPPSSPY FSGDFSSTTD ASGESITAPT
1660 1670 1680 1690 1700
GSGETSGLPE VTLITSELVE GVTEPTVSQE LGHGPSMTYT PRLFEASGEA
1710 1720 1730 1740 1750
SASGDLGGPV TIFPGSGVEA SVPEGSSDPS AYPEAGVGVS AAPEASSQLS
1760 1770 1780 1790 1800
EFPDLHGITS ASRETDLEMT TPGTEVSSNP WTFQEGTREG SAAPEVSGES
1810 1820 1830 1840 1850
STTSDIDAGT SGVPFATPMT SGDRTEISGE WSDHTSEVNV TVSTTVPESR
1860 1870 1880 1890 1900
WAQSTQHPTE TLQEIGSPNP SYSGEETQTA ETAKSLTDTP TLASPEGSGE
1910 1920 1930 1940 1950
TESTAADQEQ CEEGWTKFQG HCYRHFPDRE TWVDAERRCR EQQSHLSSIV
1960 1970 1980 1990 2000
TPEEQEFVNK NAQDYQWIGL NDRTIEGDFR WSDGHSLQFE KWRPNQPDNF
2010 2020 2030 2040 2050
FATGEDCVVM IWHERGEWND VPCNYQLPFT CKKGTVACGE PPAVEHARTL
2060 2070 2080 2090 2100
GQKKDRYEIS SLVRYQCTEG FVQRHVPTIR CQPSGHWEEP RITCTDPNTY
2110 2120
KHRLQKRSMR PTRRSRPSMA H
Length:2,121
Mass (Da):220,565
Last modified:April 3, 2013 - v2
Checksum:i6DDD5BB2F6644FC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06006559 Genomic DNA. No translation available.
AABR06006560 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000049681; ENSRNOP00000044130; ENSRNOG00000028992.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06006559 Genomic DNA. No translation available.
AABR06006560 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000049681 ; ENSRNOP00000044130 ; ENSRNOG00000028992 .

Organism-specific databases

RGDi 68358. Acan.

Phylogenomic databases

GeneTreei ENSGT00760000119025.

Miscellaneous databases

NextBioi 35576452.

Gene expression databases

ExpressionAtlasi F1LQI4. baseline.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.10.100.10. 5 hits.
InterProi IPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
IPR000538. Link.
IPR000436. Sushi_SCR_CCP.
[Graphical view ]
Pfami PF00059. Lectin_C. 1 hit.
PF00084. Sushi. 1 hit.
PF07686. V-set. 1 hit.
PF00193. Xlink. 4 hits.
[Graphical view ]
PRINTSi PR01265. LINKMODULE.
SMARTi SM00032. CCP. 1 hit.
SM00034. CLECT. 1 hit.
SM00406. IGv. 1 hit.
SM00445. LINK. 4 hits.
[Graphical view ]
SUPFAMi SSF56436. SSF56436. 5 hits.
SSF57535. SSF57535. 1 hit.
PROSITEi PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
PS01241. LINK_1. 3 hits.
PS50963. LINK_2. 4 hits.
PS50923. SUSHI. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1LQI4_RAT
AccessioniPrimary (citable) accession number: F1LQI4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: October 29, 2014
This is version 29 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3