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F1LQI4

- F1LQI4_RAT

UniProt

F1LQI4 - F1LQI4_RAT

Protein
Submitted name:

Aggrecan core protein

Gene

Acan

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 2 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. hyaluronic acid binding Source: InterPro

    GO - Biological processi

    1. cell adhesion Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Aggrecan core proteinImported
    Gene namesi
    Name:AcanImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 1

    Organism-specific databases

    RGDi68358. Acan.

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains C-type lectin domain.SAAS annotation

    Keywords - Domaini

    Immunoglobulin domainSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117329.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.10.100.10. 5 hits.
    InterProiIPR001304. C-type_lectin.
    IPR016186. C-type_lectin-like.
    IPR018378. C-type_lectin_CS.
    IPR016187. C-type_lectin_fold.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    IPR000538. Link.
    IPR000436. Sushi_SCR_CCP.
    [Graphical view]
    PfamiPF00059. Lectin_C. 1 hit.
    PF00084. Sushi. 1 hit.
    PF07686. V-set. 1 hit.
    PF00193. Xlink. 4 hits.
    [Graphical view]
    PRINTSiPR01265. LINKMODULE.
    SMARTiSM00032. CCP. 1 hit.
    SM00034. CLECT. 1 hit.
    SM00406. IGv. 1 hit.
    SM00445. LINK. 4 hits.
    [Graphical view]
    SUPFAMiSSF56436. SSF56436. 5 hits.
    SSF57535. SSF57535. 1 hit.
    PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
    PS50041. C_TYPE_LECTIN_2. 1 hit.
    PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    PS01241. LINK_1. 3 hits.
    PS50963. LINK_2. 4 hits.
    PS50923. SUSHI. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F1LQI4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTLLLVFVT LRVIAAVISE EVPDHDNSLS VSIPQPSPLK ALLGTSLTIP     50
    CYFIDPMHPV TTAPSTAPLT PRIKWSRVSK EKEVVLLVAT EGQVRVNSIY 100
    QDKVSLPNYP AIPSDATLEI QNLRSNDSGI YRCEVMHGIE DSEATLEVIV 150
    KGIVFHYRAI STRYTLDFDR AQRACLQNSA IIATPEQLQA AYEDGFHQCD 200
    AGWLADQTVR YPIHTPREGC YGDKDEFPGV RTYGIRDTNE TYDVYCFAEE 250
    MEGEVFYATS PEKFTFQEAA NECRRLGARL ATTGQLYLAW QGGMDMCSAG 300
    WLADRSVRYP ISKARPNCGG NLLGVRTVYL HANQTGYPDP SSRYDAICYT 350
    GEDFVDIPEN FFGVGGEEDI TIQTVTWPDL ELPLPRNITE GEARGNVILT 400
    AKPIFDMSPT VSEPGEALTL APEVGTTVFP EAGERTEKTT RPWGFPEEAT 450
    RGPDSATAFA SEDLVVRVTI SPGAVEVPGQ PRLPGGVVFH YRPGSTRYSL 500
    TFEEAQQACI RTGAAIASPE QLQAAGYEQC DAGWLXXXTV XYPIVSPRTP 550
    CVGDKDSSPG VRTYGVRPSS ETYDVYCYVD KLEGEVFFAT QMEQFTFQEA 600
    QAFCAAQNAT LASTGQLYAA WSQGLDKCYA GWLADGTLRY PIVNPRPACG 650
    GDKPGVRTVY LYPNQTGLPD PLSKHHAFCF RGVSVAPSPG GTPTSPSDIE 700
    DWIVTRVEPG VDAVPLEPET TEVPYFTTEP EKQTEWEPAY TPVGTSPLPG 750
    IPPTWLPTVP AAEEHTESPS ASQEPSASQV PSTSEEPYTP SLAVPSGTEL 800
    PSSGDTSGAP DLSGDFTGST DTSGRLDSSG EPSGGSESGL PSGDLDSSGL 850
    GPTVSSGLPV ESGSASGDGE IPWSSTPTVG RLPSGGESLE GSASASGTGD 900
    LSGLPSGGEI TETSASGTEE ISGLPSGGDD LETSTSGIDG ASVLPTGRGG 950
    LETSASGVED LSGLPSGEEG SETSTSGIED ISVLPTGESP ETSASGVGDL 1000
    SGLPSGGESL ETSASGVEDV TQLPTERGGL ETSASGIEDI TVLPTGRENL 1050
    ETSASGVEDV SGLPSGKEGL ETSASGIEDI SVFPTEAEGL ETSASGGYVS 1100
    GIPSGEDGTE TSTSGVEGVS GLPSGGEGLE TSASGVEDLG LPTRDSLETS 1150
    ASGVDVTGYP SGREDTETSV PGVGDDLSGL PSGQEGLETS ASGAEDLGGL 1200
    PSGKEDLVGS ASGALDFGKL PSGTLGSGQT PEASGLPSGF SGEYSGVDIG 1250
    SGPSSGLPDF SGLPSGFPTV SLVDSTLVEV ITATTASELE GRGTISVSGS 1300
    GEESGPPLSE LDSSADISGL PSGTELSGQT SGSLDVSGET SGFFDVSGQP 1350
    FGSSGTGEGT SGIPEVSGQP SGSPDTTEIS ELSGLSSGQP DVSGEGSGIL 1400
    FGSGQSSGIT SVSGETSGIS DLSGQPSGFP VLSGTTPGTP DLASGAMSGS 1450
    GDSSGITFVD TSLIEVTPTT FREEEGLGSV ELSGLPSGET DLSGTSGMVD 1500
    VSGQSSGAID SSGLISPTPE FSGLPSGVAE VSGEVSGVET GSSLSSGAFD 1550
    GSGLVSGFPT VSLVDRTLVE SITLAPTAQE AGEGPSSILE FSGAHSGTPD 1600
    ISGDLSGSLD QSTWQPGWTE ASTEPPSSPY FSGDFSSTTD ASGESITAPT 1650
    GSGETSGLPE VTLITSELVE GVTEPTVSQE LGHGPSMTYT PRLFEASGEA 1700
    SASGDLGGPV TIFPGSGVEA SVPEGSSDPS AYPEAGVGVS AAPEASSQLS 1750
    EFPDLHGITS ASRETDLEMT TPGTEVSSNP WTFQEGTREG SAAPEVSGES 1800
    STTSDIDAGT SGVPFATPMT SGDRTEISGE WSDHTSEVNV TVSTTVPESR 1850
    WAQSTQHPTE TLQEIGSPNP SYSGEETQTA ETAKSLTDTP TLASPEGSGE 1900
    TESTAADQEQ CEEGWTKFQG HCYRHFPDRE TWVDAERRCR EQQSHLSSIV 1950
    TPEEQEFVNK NAQDYQWIGL NDRTIEGDFR WSDGHSLQFE KWRPNQPDNF 2000
    FATGEDCVVM IWHERGEWND VPCNYQLPFT CKKGTVACGE PPAVEHARTL 2050
    GQKKDRYEIS SLVRYQCTEG FVQRHVPTIR CQPSGHWEEP RITCTDPNTY 2100
    KHRLQKRSMR PTRRSRPSMA H 2121
    Length:2,121
    Mass (Da):220,565
    Last modified:April 3, 2013 - v2
    Checksum:i6DDD5BB2F6644FC8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06006559 Genomic DNA. No translation available.
    AABR06006560 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSRNOT00000049681; ENSRNOP00000044130; ENSRNOG00000028992.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06006559 Genomic DNA. No translation available.
    AABR06006560 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000049681 ; ENSRNOP00000044130 ; ENSRNOG00000028992 .

    Organism-specific databases

    RGDi 68358. Acan.

    Phylogenomic databases

    GeneTreei ENSGT00750000117329.

    Miscellaneous databases

    NextBioi 35576452.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.10.100.10. 5 hits.
    InterProi IPR001304. C-type_lectin.
    IPR016186. C-type_lectin-like.
    IPR018378. C-type_lectin_CS.
    IPR016187. C-type_lectin_fold.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR013106. Ig_V-set.
    IPR003596. Ig_V-set_subgr.
    IPR000538. Link.
    IPR000436. Sushi_SCR_CCP.
    [Graphical view ]
    Pfami PF00059. Lectin_C. 1 hit.
    PF00084. Sushi. 1 hit.
    PF07686. V-set. 1 hit.
    PF00193. Xlink. 4 hits.
    [Graphical view ]
    PRINTSi PR01265. LINKMODULE.
    SMARTi SM00032. CCP. 1 hit.
    SM00034. CLECT. 1 hit.
    SM00406. IGv. 1 hit.
    SM00445. LINK. 4 hits.
    [Graphical view ]
    SUPFAMi SSF56436. SSF56436. 5 hits.
    SSF57535. SSF57535. 1 hit.
    PROSITEi PS00615. C_TYPE_LECTIN_1. 1 hit.
    PS50041. C_TYPE_LECTIN_2. 1 hit.
    PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    PS01241. LINK_1. 3 hits.
    PS50963. LINK_2. 4 hits.
    PS50923. SUSHI. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiF1LQI4_RAT
    AccessioniPrimary (citable) accession number: F1LQI4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 28 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3