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Protein
Submitted name:

Cytochrome P450 11B2, mitochondrial

Gene

Cyp11b2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-RNO-193993. Mineralocorticoid biosynthesis.
R-RNO-194002. Glucocorticoid biosynthesis.
R-RNO-211976. Endogenous sterols.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 11B2, mitochondrialImported
Gene namesi
Name:Cyp11b2Imported
Synonyms:Cyp11b3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi2454. Cyp11b2.
727886. Cyp11b3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1LPS4.

Expressioni

Gene expression databases

BgeeiENSRNOG00000030111.
ExpressionAtlasiF1LPS4. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0159. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000119243.
OMAiPFEAMPQ.
OrthoDBiEOG091G0B8F.
TreeFamiTF105094.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002399. Cyt_P450_mitochondrial.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00408. MITP450.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LPS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRVTADVW LARPWQCLHR TRALGTTATL APKTLKPFEA IPQYSRNKWL
60 70 80 90 100
KMIQILREQG QENLHLEMHQ AFQELGPIFR HSAGGAQIVS VMLPEDAEKL
110 120 130 140 150
HQVESILPRR MHLEPWVAHR ELRGLRRGVF LLNGADWRFN RLKLNPNVLS
160 170 180 190 200
PKAVQNFVPM VDEVARDFLE ALKKKVRQNA RGSLTMDVQQ SLFNYTIEAS
210 220 230 240 250
NFALFGERLG LLGHDLNPGS LKFIHALHSM FKSTTQLLFL PRSLTRWTST
260 270 280 290 300
RVWKEHFDAW DVISEYANRC IWKVHQELRL GSSQTYSGIV AALITQGALP
310 320 330 340 350
LDAIKANSME LTAGSVDTTA IPLVMTLFEL ARNPDVQQAL RQETLAAEAS
360 370 380 390 400
IAANPQKAMS DLPLLRAALK ETLRLYPVGG FLERILNSDL VLQNYHVPAG
410 420 430 440 450
TLVLLYLYSM GRNPAVFPRP ERYMPQRWLE RKRSFQHLAF GFGVRQCLGR
460 470 480 490 500
RLAEVEMLLL LHHMLKTFQV ETLRQEDVQM AYRFVLMPSS SPVLTFRPVS
Length:500
Mass (Da):57,123
Last modified:May 3, 2011 - v1
Checksum:i2A9C284822C88BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058430 Genomic DNA. No translation available.
AABR07058431 Genomic DNA. No translation available.
AABR07058432 Genomic DNA. No translation available.
AABR07058433 Genomic DNA. No translation available.
AABR07058434 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000041774; ENSRNOP00000049722; ENSRNOG00000030111.

Similar proteinsi

Entry informationi

Entry nameiF1LPS4_RAT
AccessioniPrimary (citable) accession number: F1LPS4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 27, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported