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F1LP76

- F1LP76_RAT

UniProt

F1LP76 - F1LP76_RAT

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Protein
Submitted name:

Elongator complex protein 1

Gene

Ikbkap

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl
  2. kinase activity Source: UniProtKB-KW
  3. phosphorylase kinase regulator activity Source: Ensembl

GO - Biological processi

  1. positive regulation of cell migration Source: Ensembl
  2. transcription elongation from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Elongator complex protein 1Imported
Submitted name:
Inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein, isoform CRA_aImported
Gene namesi
Name:IkbkapImported
ORF Names:rCG_31928Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 5

Organism-specific databases

RGDi620072. Ikbkap.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. DNA-directed RNA polymerase II, holoenzyme Source: Ensembl
  3. Elongator holoenzyme complex Source: Ensembl
  4. nucleolus Source: Ensembl
  5. transcription elongation factor complex Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000013344.
OMAiTREVKNE.
OrthoDBiEOG7BCN9X.
TreeFamiTF300402.

Family and domain databases

Gene3Di2.120.10.30. 2 hits.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR006849. IKI3.
[Graphical view]
PANTHERiPTHR12747. PTHR12747. 1 hit.
PfamiPF04762. IKI3. 1 hit.
[Graphical view]
PIRSFiPIRSF017233. IKAP. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LP76-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRNLKLHQTL EFRDIQAPGK PQCFCLRAEQ GTVLIGSERG LTEVDPVKKE
60 70 80 90 100
VKTEISLVAE GFLPEDGSGC IVGIQDLLDQ ESVCVATASG DVIVCNVSTQ
110 120 130 140 150
QLECVGNVAS GISVMSWSPD QELLLLATAQ QTLIMMTRDY EVITEQQIHQ
160 170 180 190 200
DDFGEGKFIT VGWGSKDTQF HGSEGRPITF PVQMHESALS WDDHRPQITW
210 220 230 240 250
RGDGQFFAVS VVCSQTGARK IRVWNREFAL QSTSESVPGL GPSLAWKPSG
260 270 280 290 300
SLIASTQDKP NQQDVVFFEK NGLLHGYFTL PFLKDEVKVN DLLWNADSSV
310 320 330 340 350
LAVWLEDLPK EGSSTLKSYV QLWTVGNYHW YLKQSLPFST TGKNQIVSLL
360 370 380 390 400
WDPVTPGRLH VLCQGWRYLC CDWHWTTDRS SGNSADDLAN VAVIDGNKVL
410 420 430 440 450
VTVFQRTVTP PPMCTYRLLI PHPVNQVMFS AHLGNDLAVL DASNQISVYK
460 470 480 490 500
CDDKPDMDST VKLGAVGGTG FKVPLRTPHL EKRYRIQFGN KEEEEDVSPL
510 520 530 540 550
QFRFLTWIEG DAFLAISHSH SSPQSIIHHL TMAGSEGDEE QGQLNVSSSV
560 570 580 590 600
TVDGVVIGLC CCSKTKSSAV QLADGQVLKY LWESPSSAVE PWKNSEGRPV
610 620 630 640 650
RFARPCTQME AAAIGGEECV LGLTDRCRFF INDTEVASNI TSFAVCDDFL
660 670 680 690 700
LVTTHSHTCQ CFSLSGASLK MLQAGLCGSQ VPSGEILRKV ERGSRIVTVV
710 720 730 740 750
PQDTKLILQM PRGNLEVVHH RALVLAQIRK WLDKLMFKEA FECMRKLRIN
760 770 780 790 800
LNLIHDHNPK VFLENVETFI KQIDSVNHLN LFFTELKEED VTKTMYPPPV
810 820 830 840 850
TKSVQVSTNP DGKKVDLICD AMRVAMETIN PRKFCLSILT SHVKKTTPEL
860 870 880 890 900
DIVLQKVHEL QGKIPFEPES VSAEEALKYL LLLVDVNELF NHSLGTYDFD
910 920 930 940 950
LVLMVAEKSQ KDPKEYLPFL NTLKKMETNY QRFTIDKYLK RYEKALGHLS
960 970 980 990 1000
KCGPEYFTEC LNLIKDKNLY KEALKLYRPD SPQYQAVSVA YGEHLVQEHL
1010 1020 1030 1040 1050
YEPAGLVFAR CGAHEKALEA FLACGSWQQA LCMAAQLQMA KDKVAGLART
1060 1070 1080 1090 1100
LAGKLVEQRK HSEAATVLEQ YAQDYEEAVL LLLEGSAWEE ALRLVYKYDR
1110 1120 1130 1140 1150
VDIIETSVKP SILEAQKNYM DFLDSQTATF IRHKNRLKVV RELKSQAPRV
1160 1170 1180 1190 1200
HVDHEVAHGR ETDLFSETSS IRSGSEMSGR YSHSNSRISA RSSKNRRKAE
1210 1220 1230 1240 1250
RKKHSLKEGS PLEGLALLEA LSEVVQSIEK LKDEVHAILK VLFLFEFEEQ
1260 1270 1280 1290 1300
ARELQRAFES TLQLMGTALP DIWTLTGQQS SATPVLGPSS TVNSIMASYQ
1310 1320 1330
QQKTCVPVLD AWACLPPKID QRSQWKLSLL E
Length:1,331
Mass (Da):149,199
Last modified:April 3, 2013 - v2
Checksum:iFEA210441C537C69
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06037256 Genomic DNA. No translation available.
CH474039 Genomic DNA. Translation: EDL91690.1.
UniGeneiRn.162816.

Genome annotation databases

EnsembliENSRNOT00000022836; ENSRNOP00000022836; ENSRNOG00000016725.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06037256 Genomic DNA. No translation available.
CH474039 Genomic DNA. Translation: EDL91690.1 .
UniGenei Rn.162816.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000022836 ; ENSRNOP00000022836 ; ENSRNOG00000016725 .

Organism-specific databases

RGDi 620072. Ikbkap.

Phylogenomic databases

GeneTreei ENSGT00390000013344.
OMAi TREVKNE.
OrthoDBi EOG7BCN9X.
TreeFami TF300402.

Miscellaneous databases

NextBioi 35576041.
PROi F1LP76.

Family and domain databases

Gene3Di 2.120.10.30. 2 hits.
InterProi IPR011042. 6-blade_b-propeller_TolB-like.
IPR006849. IKI3.
[Graphical view ]
PANTHERi PTHR12747. PTHR12747. 1 hit.
Pfami PF04762. IKI3. 1 hit.
[Graphical view ]
PIRSFi PIRSF017233. IKAP. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1LP76_RAT
AccessioniPrimary (citable) accession number: F1LP76
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: October 29, 2014
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3