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F1LP76

- F1LP76_RAT

UniProt

F1LP76 - F1LP76_RAT

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Protein
Submitted name:

Elongator complex protein 1

Gene
Ikbkap, rCG_31928
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl
  2. kinase activity Source: UniProtKB-KW
  3. phosphorylase kinase regulator activity Source: Ensembl

GO - Biological processi

  1. positive regulation of cell migration Source: Ensembl
  2. transcription elongation from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Elongator complex protein 1Imported
Submitted name:
Inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein, isoform CRA_aImported
Gene namesi
Name:IkbkapImported
ORF Names:rCG_31928Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 5

Organism-specific databases

RGDi620072. Ikbkap.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. DNA-directed RNA polymerase II, holoenzyme Source: Ensembl
  3. Elongator holoenzyme complex Source: Ensembl
  4. nucleolus Source: Ensembl
  5. transcription elongation factor complex Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000013344.
OMAiTREVKNE.
OrthoDBiEOG7BCN9X.
TreeFamiTF300402.

Family and domain databases

Gene3Di2.120.10.30. 2 hits.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR006849. IKI3.
[Graphical view]
PANTHERiPTHR12747. PTHR12747. 1 hit.
PfamiPF04762. IKI3. 1 hit.
[Graphical view]
PIRSFiPIRSF017233. IKAP. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LP76-1 [UniParc]FASTAAdd to Basket

« Hide

MRNLKLHQTL EFRDIQAPGK PQCFCLRAEQ GTVLIGSERG LTEVDPVKKE     50
VKTEISLVAE GFLPEDGSGC IVGIQDLLDQ ESVCVATASG DVIVCNVSTQ 100
QLECVGNVAS GISVMSWSPD QELLLLATAQ QTLIMMTRDY EVITEQQIHQ 150
DDFGEGKFIT VGWGSKDTQF HGSEGRPITF PVQMHESALS WDDHRPQITW 200
RGDGQFFAVS VVCSQTGARK IRVWNREFAL QSTSESVPGL GPSLAWKPSG 250
SLIASTQDKP NQQDVVFFEK NGLLHGYFTL PFLKDEVKVN DLLWNADSSV 300
LAVWLEDLPK EGSSTLKSYV QLWTVGNYHW YLKQSLPFST TGKNQIVSLL 350
WDPVTPGRLH VLCQGWRYLC CDWHWTTDRS SGNSADDLAN VAVIDGNKVL 400
VTVFQRTVTP PPMCTYRLLI PHPVNQVMFS AHLGNDLAVL DASNQISVYK 450
CDDKPDMDST VKLGAVGGTG FKVPLRTPHL EKRYRIQFGN KEEEEDVSPL 500
QFRFLTWIEG DAFLAISHSH SSPQSIIHHL TMAGSEGDEE QGQLNVSSSV 550
TVDGVVIGLC CCSKTKSSAV QLADGQVLKY LWESPSSAVE PWKNSEGRPV 600
RFARPCTQME AAAIGGEECV LGLTDRCRFF INDTEVASNI TSFAVCDDFL 650
LVTTHSHTCQ CFSLSGASLK MLQAGLCGSQ VPSGEILRKV ERGSRIVTVV 700
PQDTKLILQM PRGNLEVVHH RALVLAQIRK WLDKLMFKEA FECMRKLRIN 750
LNLIHDHNPK VFLENVETFI KQIDSVNHLN LFFTELKEED VTKTMYPPPV 800
TKSVQVSTNP DGKKVDLICD AMRVAMETIN PRKFCLSILT SHVKKTTPEL 850
DIVLQKVHEL QGKIPFEPES VSAEEALKYL LLLVDVNELF NHSLGTYDFD 900
LVLMVAEKSQ KDPKEYLPFL NTLKKMETNY QRFTIDKYLK RYEKALGHLS 950
KCGPEYFTEC LNLIKDKNLY KEALKLYRPD SPQYQAVSVA YGEHLVQEHL 1000
YEPAGLVFAR CGAHEKALEA FLACGSWQQA LCMAAQLQMA KDKVAGLART 1050
LAGKLVEQRK HSEAATVLEQ YAQDYEEAVL LLLEGSAWEE ALRLVYKYDR 1100
VDIIETSVKP SILEAQKNYM DFLDSQTATF IRHKNRLKVV RELKSQAPRV 1150
HVDHEVAHGR ETDLFSETSS IRSGSEMSGR YSHSNSRISA RSSKNRRKAE 1200
RKKHSLKEGS PLEGLALLEA LSEVVQSIEK LKDEVHAILK VLFLFEFEEQ 1250
ARELQRAFES TLQLMGTALP DIWTLTGQQS SATPVLGPSS TVNSIMASYQ 1300
QQKTCVPVLD AWACLPPKID QRSQWKLSLL E 1331
Length:1,331
Mass (Da):149,199
Last modified:April 3, 2013 - v2
Checksum:iFEA210441C537C69
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06037256 Genomic DNA. No translation available.
CH474039 Genomic DNA. Translation: EDL91690.1.
UniGeneiRn.162816.

Genome annotation databases

EnsembliENSRNOT00000022836; ENSRNOP00000022836; ENSRNOG00000016725.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06037256 Genomic DNA. No translation available.
CH474039 Genomic DNA. Translation: EDL91690.1 .
UniGenei Rn.162816.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000022836 ; ENSRNOP00000022836 ; ENSRNOG00000016725 .

Organism-specific databases

RGDi 620072. Ikbkap.

Phylogenomic databases

GeneTreei ENSGT00390000013344.
OMAi TREVKNE.
OrthoDBi EOG7BCN9X.
TreeFami TF300402.

Miscellaneous databases

NextBioi 35576041.
PROi F1LP76.

Family and domain databases

Gene3Di 2.120.10.30. 2 hits.
InterProi IPR011042. 6-blade_b-propeller_TolB-like.
IPR006849. IKI3.
[Graphical view ]
PANTHERi PTHR12747. PTHR12747. 1 hit.
Pfami PF04762. IKI3. 1 hit.
[Graphical view ]
PIRSFi PIRSF017233. IKAP. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiF1LP76_RAT
AccessioniPrimary (citable) accession number: F1LP76
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: April 16, 2014
This is version 24 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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