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F1LP76

- F1LP76_RAT

UniProt

F1LP76 - F1LP76_RAT

Protein
Submitted name:

Elongator complex protein 1

Gene

Ikbkap

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 2 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: Ensembl
    2. kinase activity Source: UniProtKB-KW
    3. phosphorylase kinase regulator activity Source: Ensembl

    GO - Biological processi

    1. positive regulation of cell migration Source: Ensembl
    2. transcription elongation from RNA polymerase II promoter Source: Ensembl

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Elongator complex protein 1Imported
    Submitted name:
    Inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein, isoform CRA_aImported
    Gene namesi
    Name:IkbkapImported
    ORF Names:rCG_31928Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 5

    Organism-specific databases

    RGDi620072. Ikbkap.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. DNA-directed RNA polymerase II, holoenzyme Source: Ensembl
    3. Elongator holoenzyme complex Source: Ensembl
    4. nucleolus Source: Ensembl
    5. transcription elongation factor complex Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000013344.
    OMAiTREVKNE.
    OrthoDBiEOG7BCN9X.
    TreeFamiTF300402.

    Family and domain databases

    Gene3Di2.120.10.30. 2 hits.
    InterProiIPR011042. 6-blade_b-propeller_TolB-like.
    IPR006849. IKI3.
    [Graphical view]
    PANTHERiPTHR12747. PTHR12747. 1 hit.
    PfamiPF04762. IKI3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF017233. IKAP. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F1LP76-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRNLKLHQTL EFRDIQAPGK PQCFCLRAEQ GTVLIGSERG LTEVDPVKKE     50
    VKTEISLVAE GFLPEDGSGC IVGIQDLLDQ ESVCVATASG DVIVCNVSTQ 100
    QLECVGNVAS GISVMSWSPD QELLLLATAQ QTLIMMTRDY EVITEQQIHQ 150
    DDFGEGKFIT VGWGSKDTQF HGSEGRPITF PVQMHESALS WDDHRPQITW 200
    RGDGQFFAVS VVCSQTGARK IRVWNREFAL QSTSESVPGL GPSLAWKPSG 250
    SLIASTQDKP NQQDVVFFEK NGLLHGYFTL PFLKDEVKVN DLLWNADSSV 300
    LAVWLEDLPK EGSSTLKSYV QLWTVGNYHW YLKQSLPFST TGKNQIVSLL 350
    WDPVTPGRLH VLCQGWRYLC CDWHWTTDRS SGNSADDLAN VAVIDGNKVL 400
    VTVFQRTVTP PPMCTYRLLI PHPVNQVMFS AHLGNDLAVL DASNQISVYK 450
    CDDKPDMDST VKLGAVGGTG FKVPLRTPHL EKRYRIQFGN KEEEEDVSPL 500
    QFRFLTWIEG DAFLAISHSH SSPQSIIHHL TMAGSEGDEE QGQLNVSSSV 550
    TVDGVVIGLC CCSKTKSSAV QLADGQVLKY LWESPSSAVE PWKNSEGRPV 600
    RFARPCTQME AAAIGGEECV LGLTDRCRFF INDTEVASNI TSFAVCDDFL 650
    LVTTHSHTCQ CFSLSGASLK MLQAGLCGSQ VPSGEILRKV ERGSRIVTVV 700
    PQDTKLILQM PRGNLEVVHH RALVLAQIRK WLDKLMFKEA FECMRKLRIN 750
    LNLIHDHNPK VFLENVETFI KQIDSVNHLN LFFTELKEED VTKTMYPPPV 800
    TKSVQVSTNP DGKKVDLICD AMRVAMETIN PRKFCLSILT SHVKKTTPEL 850
    DIVLQKVHEL QGKIPFEPES VSAEEALKYL LLLVDVNELF NHSLGTYDFD 900
    LVLMVAEKSQ KDPKEYLPFL NTLKKMETNY QRFTIDKYLK RYEKALGHLS 950
    KCGPEYFTEC LNLIKDKNLY KEALKLYRPD SPQYQAVSVA YGEHLVQEHL 1000
    YEPAGLVFAR CGAHEKALEA FLACGSWQQA LCMAAQLQMA KDKVAGLART 1050
    LAGKLVEQRK HSEAATVLEQ YAQDYEEAVL LLLEGSAWEE ALRLVYKYDR 1100
    VDIIETSVKP SILEAQKNYM DFLDSQTATF IRHKNRLKVV RELKSQAPRV 1150
    HVDHEVAHGR ETDLFSETSS IRSGSEMSGR YSHSNSRISA RSSKNRRKAE 1200
    RKKHSLKEGS PLEGLALLEA LSEVVQSIEK LKDEVHAILK VLFLFEFEEQ 1250
    ARELQRAFES TLQLMGTALP DIWTLTGQQS SATPVLGPSS TVNSIMASYQ 1300
    QQKTCVPVLD AWACLPPKID QRSQWKLSLL E 1331
    Length:1,331
    Mass (Da):149,199
    Last modified:April 3, 2013 - v2
    Checksum:iFEA210441C537C69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06037256 Genomic DNA. No translation available.
    CH474039 Genomic DNA. Translation: EDL91690.1.
    UniGeneiRn.162816.

    Genome annotation databases

    EnsembliENSRNOT00000022836; ENSRNOP00000022836; ENSRNOG00000016725.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06037256 Genomic DNA. No translation available.
    CH474039 Genomic DNA. Translation: EDL91690.1 .
    UniGenei Rn.162816.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000022836 ; ENSRNOP00000022836 ; ENSRNOG00000016725 .

    Organism-specific databases

    RGDi 620072. Ikbkap.

    Phylogenomic databases

    GeneTreei ENSGT00390000013344.
    OMAi TREVKNE.
    OrthoDBi EOG7BCN9X.
    TreeFami TF300402.

    Miscellaneous databases

    NextBioi 35576041.
    PROi F1LP76.

    Family and domain databases

    Gene3Di 2.120.10.30. 2 hits.
    InterProi IPR011042. 6-blade_b-propeller_TolB-like.
    IPR006849. IKI3.
    [Graphical view ]
    PANTHERi PTHR12747. PTHR12747. 1 hit.
    Pfami PF04762. IKI3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF017233. IKAP. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiF1LP76_RAT
    AccessioniPrimary (citable) accession number: F1LP76
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 25 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3